Isotonix® Activated B-Complex

Isotonix® Activated B-Complex

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Product Brochure

  • Contains activated forms of select B vitamins to ensure optimal utilization by the body
  • Helps decrease stress and improve mood
  • Helps maintain healthy levels of serotonin
  • Increases energy
  • Meets need for B vitamins in a vegetarian diet
  • Promotes cardiovascular health
  • Promotes healthy levels of homocysteine
  • Promotes normal cognitive performance

Product Information

Isotonix® Activated B-Complex

Vitamin B benefits go way beyond energy. For example, vitamin B12 helps support your cardiovascular health, while vitamin B6 can help maintain your immune system. Isotonix Activated B-Complex delivers active forms of these and other crucial B vitamins, providing your body with these vital nutrients quickly and effectively.

A truly great complex B vitamin formula provides a mixture of eight essential B vitamins important for hundreds of biochemical reactions in the body. When our bodies don't get enough vitamin B benefits - because of our diets, our lifestyles or a combination thereof - we can become more fatigued and lethargic. Instead of reaching for a single stress supplement or sugary energy drink to keep you going, a complex B vitamin supplement like Isotonix Activated B-Complex is an excellent energy booster and anti-stress formula rolled in one.

While most traditional forms of vitamins B6, B12 and folic acid found in most other complex B vitamin products must undergo chemical changes in order to be utilized by the body, the formula in Isotonix Activated B-Complex does not. Isotonix Activated B-Complex already provides the metabolically active forms of these vitamins in isotonic form, making it easier for the vitamins and nutrients in Isotonix Activated B-Complex to be absorbed and used in the body's metabolism, helping you get the most vitamin B benefits out of your supplement.

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

By delivering activated forms of B vitamins in an Isotonic delivery system, Isotonix Activated B Complex delivers benefits to the body quicker and easier than other B vitamin supplements in pill form. A mixture of the eight essential B-vitamins that are important in many bodily functions, this product also delivers metabolically active forms of several vitamins, therefore enhancing the effectiveness of the formulation. In comparison, other B complex products contain traditional forms of vitamins B6, B12 and folic acid. In order to be used by the body these traditional forms must undergo chemical changes and as a result, these changes limit the efficiency of the product.

SHOP.COM Reviews

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Felt energised straightaway

by MariaK


I was feeling really drained every morning regardless of how little or how much sleep I got. I decided to test out the Advanced Vitamin B Complex and straightaway felt energised and more alert. I didn't think much of it until my colleagues mentioned that I had been happier, less stressed, less moody and looked less drained in the morning. I now feel a (negative) difference in my performance at wor

Get the most for your money!

by DanielleF

Shop Consultant


These Isotonic supplements are the highest potency I've ever taken. There is no way to get this much content in your system with a tablet or capsule. I'm sold!


by yeemonk

Shop Consultant


I love the quality of Isotonix products. It has been in great conditions to store and maintain for a long time, until recently. I purchased the products like I usually do every month except for the past few months, the products has came in either frozen or turned to liquid. When I opened the seal, the powders were already stuck together and it was hard to get it out of the container. Some were mel

My go to for energy boost

by JessicaD

Shop Consultant


A great source of energy. Taste great. This is my go to product for a pick me up.

Great Energy Product - Easy to Use

by TheresaK


I use Isotonix before my workout and before my yoga classes. It is easy to use, one capful in the cup that is included with the product. Uses only 2 ounces of water and mixes easily. It tastes good. I love the fact that my body absorbs it quickly and I feel energized to do my workouts. The B vitamins also keep me calm and focused.


Methylcobalamin (Vitamin B12) (120 mcg)
Vitamin B12 (cobalamin) is a bacterial product naturally found in animal products, especially organ meats, such as liver, with small amounts derived from peanuts and fermented soy products, such as miso and tempeh. It is essential that vegetarians consume a vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. It supports the maintenance of cells, especially those of the nervous system, bone marrow and intestinal tract. Vitamin B12 is important in homocysteine metabolism (homocysteine is an amino acid that is formed within the body). Normal homocysteine levels are important for maintaining cardiovascular health. Deficiencies of the vitamins folic acid, pyridoxine (B6) or cobalamin (B12) can result in elevated levels of homocysteine. Folate and B12, in their active coenzyme form, are both necessary cofactors for the conversion of homocysteine to methionine, thus helping to maintain healthy blood levels of homocysteine.*

Methylcobalamin is one of the naturally-occurring forms of vitamin B12 found in the human body. The liver must convert cyanocobalamin, the form of B12 most commonly used in supplements, into methylcobalamin, before it can be properly utilized by the body; methylcobalamin is more effective than non-active forms of vitamin B12. Methylcobalamin also assists in the formation of SAMe (S-adenosylmethionine), a nutrient that has powerful mood-elevating properties.* 

Folate [as (6S)-5-methyltetrahydrofolic acid, glucosamine salt, Quatrefolic®] (432 mcg)
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans, peas and Brewer’s yeast are the best sources. Folic acid plays a key role by boosting the benefits of B12 supplementation. These two B vitamins join forces and work together in maintaining normal red blood cells. Folic acid assists in the normal utilization of amino acids and proteins, as well as supporting the construction of the material for DNA and RNA synthesis, which is necessary for all bodily functions. Scientific studies have found that when working in tandem with folic acid, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system.* Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate, the most active form of folate, as it is structurally analogous to the reduced and active form of folic acid. Because this form is naturally present in the body, it is much more bioavailable for its biological action without having to be metabolized in the body. This patented ingredient also provides greater stability and higher water solubility, perfect for Isotonix.*

Riboflavin-5-Phosphate (Vitamin B2) (3 mg)

Vitamin B2 is found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a coenzyme, working with other B vitamins. It promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth. It supports healthy skin, nails, hair growth and promotes normal thyroid activity (a healthy thyroid is essential in maintaining a healthy weight, among other things). Vitamin B2 supports the body's ability to in turn food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women, as well as athletes due to their higher caloric needs. Vitamin B2 also promotes the normal breakdown of fats. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.*

Pyridoxal-5-Phosphate (Vitamin B6) (6 mg)
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. B6 is a co-factor required for protein and amino acid metabolism, and helps maintain proper fluid balance. It also assists in the maintenance of healthy red and white blood cells, which keeps our body healthy. Vitamin B6 promotes normal hemoglobin synthesis (hemoglobin is the protein portion of red blood cells which carries oxygen throughout the body). Because vitamin B6 is involved in the synthesis of neurotransmitters in the brain and nerve cells, it has been recommended as a nutrient to support mental function, specifically mood. Athletic supplements often include vitamin B6 because it promotes the conversion of glycogen to glucose for energy in muscle tissue. Vitamin B6, when taken with folic acid, has been shown to help maintain normal plasma levels of homocysteine, which promotes optimal cardiovascular health. Vitamin B6 should be administered as a part of a complex of other B vitamins for best results.*

Magnesium (Carbonate) (40 mg)  
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green, leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, milk, refined and processed foods contain low amounts of magnesium. Recent research shows that many American diets are magnesium deficient.*

Magnesium is a component of the mineralized part of bone, and promotes the normal metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It also supports the transportation of calcium inside the cell for utilization. Magnesium promotes the normal functioning of muscle and nervous tissue, and the synthesis of all proteins, nucleic acids, nucleotides, fats and carbohydrates.*

Magnesium supports the normal release of energy from food during metabolism, regulation of body temperature, proper nerve function and helping the body handle stress. Importantly, magnesium also promotes healthy bones, teeth and normal muscle development. It works together with calcium and vitamin D to promote strong bones. Magnesium, when combined with calcium, helps support the heart muscle in maintaining a regular heartbeat and promoting normal blood pressure.* 

Potassium (Bicarbonate) (94 mg)
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, potassium promotes the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids and the maintenance of normal blood pressure.*

In 1928, it was first suggested that high potassium intake could help maintain cardiovascular health. Potassium promotes normal muscle relaxation and helps maintain normal insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes normal heartbeat. Potassium promotes the normal release of energy from protein, fat and carbohydrates during metabolism. Potassium helps maintain normal water balance, supports recovery from exercise and the elimination of wastes. Sodium and potassium are two of the most important ions in maintaining the homeostatic equilibrium of the body fluids.*

Thiamin HCl (Vitamin B1) (2 mg)
Thiamin promotes normal carbohydrate metabolism and nerve function. Thiamin is required for a healthy nervous system, and supports the production of certain neurotransmitters which have an important role in muscle function. It supports the digestive process, increases energy and helps promote mental clarity.*

D-Calcium Pantothenate (Vitamin B5) (20 mg)
Pantothenic acid (B5) promotes proper neurotransmitter activity in the brain. Pantothenic acid is also known as the anti-stress vitamin because it helps relieve physical and emotional stress, and promotes the secretion of hormones essential for optimal health.*

Niacinamide (Vitamin B3) (20 mg)
Niacin is a water-soluble vitamin necessary for many aspects of health, growth and reproduction. Niacin supports the proper functioning of the digestive system, skin and nerves. It promotes the normal conversion of food to energy. Niacin is found in dairy products, poultry, fish, lean meats, nuts, eggs, legumes, and enriched breads and cereals.*

Biotin (Vitamin B7) (300 mcg)
Biotin can be found in food sources, such as egg yolks, peanuts, beef liver, milk, cereals, almonds and Brewer’s yeast. Biotin promotes healthy cell growth, the production of fatty acids, metabolism of fats and amino acids. It supports the citric acid cycle, which is the process in which energy is generated during exercise. Biotin is also helpful in maintaining steady blood sugar levels. Biotin is often recommended for maintaining strong hair and nails.*

These 10 ingredients, combined with the superior delivery of Isotonix®, create a powerhouse B vitamin product superior to the rest on the market. Isotonix Activated B-Complex delivers all of the B vitamins along with select minerals and electrolytes to help boost energy, decrease stress, improve mood, and much more. The activated forms of select vitamins ensure maximal utilization by the body for optimal results.*


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What does “Activated” refer to in Isotonix Activated B-Complex?
Activated refers to the active forms of vitamins B6, B12 and folic acid. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, there are circumstances in which this reaction is either slowed or inhibited.

What is the source of the vitamin B12 in our Isotonix Activated B-Complex?
Vitamin B-12 is sourced from bacteria.  B12 in our diet can come from eggs or meat, or by taking supplement.  Vegetarians are recommended to take a B vitamin dietary supplement due to their lack of meat intake. 

Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body.  As people age, the ability to absorb vitamins decreases and reduced levels of these vitamins have been associated with impaired cognitive performance.  The US RDA's Human Nutrition Center on Aging claims vitamin B12 is the most important nutrient negatively affected by aging.  Since vitamin B12 plays a critical role in promoting normal energy production and nervous system function, aging individuals need to make sure they are getting enough vitamin B12 on a daily basis.*  

Is it toxic to take too much vitamin B12?
Vitamin B12 has not demonstrated any form of toxicity.  As always, we only recommend the product to be taken as directed in the instructions.*

Are there any warnings or contraindications for Isotonix Activated B-Complex?
If you are currently taking any prescription drug, have an ongoing medical condition, or are pregnant or breastfeeding, you should consult with your healthcare provider before using this product.  There are no allergens associated with this product.

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