Awake Energy Drinks
What Makes AWAKE Energy Drinks Unique? AWAKE energy drink mix is a blend of amino acids, vitamins, minerals and neurotransmitter precursors that will provide long-lasting energy and mental focus to consumers desiring an energy drink without the high caffeine, high sugar and nervous jitters associated with most other competing products.*
What Makes AWAKE Energy Drinks Unique?
AWAKE energy drink mix is a blend of amino acids, vitamins, minerals and neurotransmitter precursors that will provide long-lasting energy and mental focus to consumers desiring an energy drink without the high caffeine, high sugar and nervous jitters associated with most other competing products.*
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Primary Benefits of AWAKE Energy Drinks:*
· Provides gradual energy boost
· Improves overall endurance
· Provides antioxidant defense
· Offers cardiovascular support
· Caffeine free
· Supports mental clarity
Key Ingredients found in AWAKE Energy Drinks:
L-Tyrosine is an amino acid that is not classified as essential because it can be produced by the hydroxylation of phenylalanine in normal human metabolism. However, low levels of tyrosine have been shown to inhibit this conversion pathway thus sparing tyrosine for other functions within the body. Tyrosine is the direct precursor to dopamine and the catecholamines epinephrine and norepinephrine, norepinephrine being more important than epinephrine in the functionality of the energy drink. The conversion of tyrosine to dopamine and then norepinephrine requires the enzyme tyrosine hydroxylase and the precursors iron (of which intestinal absorption is enhanced by vitamin C), tetrahydrobiopterin (production requires vitamin C) and NAD (Niacin).
Ingestion of tyrosine promotes healthy brain cell levels of the neurotransmitters dopamine (formation requires vitamin B-6) and norepinephrine (formation requires copper and vitamin C). The effects of tyrosine can be inhibited by tryptophan as tryptophan and tyrosine compete for the same receptor sites on the capillary endothelium of brain cells prior to entering the neuron and being converted to their specific neurotransmitters. This is the reason it is important to take the product on an empty stomach. The promotion of brain cell dopamine and norepinephrine by ingestion of free form L-Tyrosine gives explanation to why tyrosine has the positive effect of increasing energy levels and elevating moods.
Choline (as Choline Bitartrate)
Choline is a precursor to the neurotransmitter acetylcholine. The conversion of choline to acetylcholine occurs by the reaction of choline with Acetyl CoA (Vitamin B-5 and Vitamin B-3 dependent) and is catalyzed by choline acetyltransferase. Ingestion of free choline has been shown to increase intracellular brain levels of choline and acetylcholine, thus helping to support a healthy rate of synaptic firing in brain cells. Increased neuronal concentrations of choline and, thus, acetylcholine through ingestion of free choline, has also been shown to enhance cognitive ability and memory by promoting the availability of beneficial levels of acetylcholine for reaction with postsynaptic receptors.
Glucuronolactone has been clinically proven to promote alertness under conditions of afternoon monotonous driving following sleep restriction the night before. It is widely known to promote mental performance, concentration and memory.
Taurine is a nonprotein amino acid and can be found in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. It is plentiful in the fluids of muscle, lungs and nerve tissue. Dietary taurine mainly comes from animal food sources, but is also present in low levels in plants and seaweeds.
It is classified as an essential amino acid used for micelle formation and fat absorption. Its important in the hydration of the body and gives an energy boost by stimulating the cells nutrient uptake and supporting normal physical reaction time. Additionally, it boosts mental alertness and enhances the ability to concentrate.
Glycine is a simple amino acid found in the body. Glycine is quite significant in the normal synthesis of proteins, peptides, purines, adenosine triphosphate (ATP), nucleic acids, porphyrins, hemoglobin, glutathione, creatine, bile salts, one-carbon fragments, glucose, glycogen, and L-serine and other amino acids. It supports the transport of noradrenalin into cells against their concentration gradient. Glycine promotes normal glycogen storage and helps maintain the health of the central nervous system.
L-Carnitine promotes the transfer of fatty acids across the mitochondrial membrane into the matrix of the mitochondria for the production of cellular energy via fatty acid oxidation. Fatty acid oxidation reactions require cofactors FAD (Riboflavin), NAD (Niacin), and CoA (Pantothenic Acid).
Carnitine supplementation could be of potential benefit under several conditions. Due to its role in promoting fatty acid transport into the mitochondria for oxidation, it is possible that elevated carnitine levels would promote a greater and faster transport of fat molecules, which would lead to the promotion of fat oxidation or use by the bodys systems. This may impact weight loss and/or endurance performance. The promotion of the use of fat for energy purposes may also result in a sparing of muscle glycogen and a subsequent enhancement of exercise performance. It is also hypothesized that supplemental carnitine may promote healthy levels of lactic acid in muscles by buffering pyruvate, extending exercise capacity before fatigue and promoting muscle comfort after exercise.
Vitamins B1, B2, B3, B5 and B6
B-Vitamins play a major role as cofactors in energy metabolism. Thiamin is a coenzyme necessary for the decarboxylation of pyruvate and alpha-ketoglutarate in the generation of ATP. Riboflavin functions as a cofactor in most oxidation-reduction reactions, fatty acid oxidation and in the electron transport chain. Niacin, as NADH, is responsible for transferring its electrons through the electron transport chain to produce ATP for energy. Pantothenic acid's primary role in energy production is as a component of CoA, which forms acetyl CoA. Vitamins B1, B2, B3 and B5 are all involved in the oxidative decarboxylation of pyruvate and AKG. Vitamin B6 is primarily involved in amino acid metabolism via transamination, decarboxylation, transsulfhydration and desulfhydration, cleavage, synthesis and racemization. Vitamin B6 is also necessary for the formation of heme.
Vitamin B-12 is important in the beta-oxidation of odd-numbered fatty acids, and the oxidation of the carbon skeletons of the amino acids methionine, threonine and isoleucine into succinyl CoA, which then enters the Krebs cycle to form GTP and thus ATP for energy.
Vitamin A, E and C
Vitamins A, C and E provide antioxidant protection from free radical damage. Vitamin A is a fat-soluble vitamin that is part of a family of compounds, including retinol, retinal and beta-carotene. Beta-carotene is also known as pro-vitamin A because it can be converted into vitamin A. The best sources of vitamin A include organ meats such as liver and kidney, egg yolks, butter, carrot juice, squash, sweet potatoes, spinach, peaches, fortified dairy products (like milk and some margarines) and cod liver oil.
Vitamin A helps to maintain vision. It promotes normal bone growth and also contributes to a healthy immune system. Vitamin A plays vital roles in epithelial differentiation, growth, reproduction, pattern formation during embryogenesis, bone development, hematopoiesis and brain development. Vitamin A also exerts a positive effect on eye health. Vitamin A supplementation promotes normal macular density. It may also help reduce minor symptoms associated with premenstrual syndrome. High-dose vitamin A has been used in to support skin health.
Vitamin C is derived from fresh fruits and vegetables. Peppers (sweet, green, red, hot red and green chili) are especially rich in vitamin C. Other good sources include citrus fruits and juices, brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries.
Benefits of vitamin C include: enhancing immune system function, promoting the absorption of iron and supporting cardiovascular health. Vitamin C is an antioxidant necessary for the growth and repair of tissue, adrenal gland function and gum health.
Vitamin E comes from vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amount of vitamin E. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols. It was discovered in the early 1930s when rats were fed a diet without the presence of vegetable oils (the primary dietary source of vitamin E), and the study resulted in reproductive problems.
Vitamin E is an immune-boosting antioxidant. It also promotes normal healing and is known to promote the health of the cardiovascular system. Vitamin E is one of the most powerful, fat-soluble antioxidants in the body, and it protects cell membranes from free radical damage.
Scientific Studies Which Support AWAKE Energy Drinks:
· Alessio, H. M., et al. Exercise-induced oxidative stress before and after vitamin C supplementation. Int J Sport Nutr 7(1):1-9, 1997.
· Arenas, J., et al. Effects of L-carnitine on the pyruvate dehydrogenase complex and carnitine palmitoyl transferase activities in muscle of endurance athletes. FEBS Lett 341(1):91-93, 1994.
· Ashi Devi, S., et al. Dietary vitamin E and physical exercise: I. Altered endurance capacity and plasma lipid profile in ageing rats. Exp Gerontol 38(3):285-290, 2003.
· Benton, D., et al. Thiamine supplementation mood and cognitive functioning. Psychopharmacology (Berlin). 129(1):66-71, 1997.
· Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition 132(6):1345-1356, 2002.
· Bunout, D., et al. Effects of Supplementation with Folic Acid and Antioxidant Vitamins on Homocysteine Levels and LDL Oxidation in Coronary Patients. Nutrition 16: 107-110, 2000.
· Conlay, L.A., et al. Exercise and neuromodulators: choline and acetylcholine in marathon runners. Int J Sports Med 13(Supplement 1):S141-S142, 1992.
· De Bree, A., et al. Association between B vitamin intake and plasma homocysteine concentration in general Dutch population aged 20-65 y. Am J Clin Nutr 73: 1027-33, 2001.
· De Bree, A., et al. Lifestyle factors and plasma homcysteine concentrations in a general population sample. American J Epidemiology 154:150-4, 2001.
· Deijen, J. B., et al. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Psychopharmacology 109(4):489-496, 1992.
· Evans S. and Griffiths R. Caffeine withdrawal: a parametric analysis of caffeine dosing conditions. Journal of Pharmacology and Experimental Therapeutics 289(1): 285-94, 1999.
· Evans, W. J. Vitamin E, vitamin C and exercise. American Journal of Clinical Nutrition 72(Supplement):S647-S652, 2000.
· Frei, B., et al. Ascorbate is an outstanding antioxidant in human blood plasma. Proceedings of the National Academy of Sciences USA 86(16):6377-6381, 1989.
· Friso, S., et al. Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk. Am J Clin Nutr 79: 992 998, 2004.
· Hartmann, A., et al. Vitamin E prevents exercise-induced DNA damage. Mutation Research 346(4):195-202, 1995.
· Heap, L. C., et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med 92(4):183-185, 1999.
· Juliano, L.M. and Griffiths R.R. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features. Psychopharmacology 176(1):1-29, 2004. Review.
· Karlic, H., et al. Supplementation of l-carnitine in athletes: does it make sense? Nutrition 20(7-8):709-715, 2004.
· McKinley, M., et al. Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete. Am J Clin Nutr 73: 759-64, 2001.
· Neri, D.F., et al. The effects of tyrosine on cognitive performance during extended wakefulness. Aviat Space Environ Med 66(4):313-319, 1995.
· Phillips-Bute, B. and Lane, J. Caffeine withdrawal symptoms following brief caffeine deprivation. Physiology and Behavior 63(1): 35-39, 1997.
· Piercy, R. J., et al. Association between vitamin E and enhanced athletic performance in sled dogs. Medicine and Science in Sports and Exercise 33(5):826-833, 2001.
· Plioplys, A. V., et al. Amantadine and L-carnitine treatment of chronic fatigue syndrome. Neuropsychobiology 35(1):16-23, 1997.
· Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
· Rimm, E., et al. Folate and Vitamin B-6 From Diet and Supplements in Relation to Risk of Coronary Heart Disease Among Women. JAMA 279: 359-64, 1998.
· Schmidt, L. J., et al. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency. J Gerontol M:16-22, 1991.
· Werbach, M. R. Nutritional strategies for treating chronic fatigue syndrome. Alternative Medicine Review 5(2):93-108, 2000.
Frequently Asked Questions about AWAKE Energy Drinks:
What ingredient in AWAKE replaces the caffeine?
All of the ingredients in AWAKE work together to promote enhanced energy. This product was formulated without caffeine.*
How does AWAKE provide Cardiovascular defense?
Taurine is an amino acid that has a positive inotropic action on cardiac tissue and has been shown to help maintain normal blood pressure levels. Also, the B vitamins have proven cardiovascular support activity.*
If AWAKE is caffeine free then how does it work to provide me the energy I need to keep moving?
The B vitamins and amino acids work to promote the production of ATP in the body which gives the body increased energy.*
Should I take AWAKE during my workout or before my workout regime?
AWAKE is an energy booster. If you want something to maximize your workout, take Torch Pre-Burn.*
How should I take this product?
Add contents of one pouch to 8 fluid ounces of cold water and shake or stir to blend. Drink 1-3 times per day, preferably between meals.
What are the contraindications for this supplement?
Possible Allergen: Soybeans and fish gelatin (cod, polluck, haddock, hake, cusk, redfish)
This product is not vegetarian. It contains fish gelatin.
Is it all natural?
Some ingredients may be synthetically produced in a laboratory to ensure purity and quality.