- Promotes normal activity of NF-KappaB
- Supports normal liver detoxification activity
- Supports overall liver health
- Promotes apoptosis in unhealthy cells
- Promotes normal cell cycle activity
- Helps maintain overall cell integrity
- Promotes normal cellular regeneration
- Helps maintain healthy glutathione levels
- Supports normal glutathione synthesis
- Promotes the normal production of detoxification enzymes
- Supports the body’s natural ability to produce detoxification enzymes
- Promotes normal levels of detoxification enzymes that scavenge harmful toxins in the body
- Helps to maintain neurological health as we age
- Helps to maintain good cognitive health as we age
- Promotes normal immune cell-brain (neuron) interactions in order to maintain cognitive health
- Promotes neurological health
- Protects neurons from the negative effects of free radicals
- Powerful antioxidant
- Protects the body from the negative effects of free radicals
- Promotes free-radical protection
- Promotes a strong immune system
- Supports joint health
- Supports relief from temporary inflammation associated with the normal aging process and daily activity
There are many curcumin products on the market, but Curcumin Extreme with BCM-95® has superior bioavailability and absorption. BCM-95 contains the natural spectrum of the turmeric rhizome and is 100 percent natural. Curcumin Extreme promotes liver detoxification, promotes healthy glutathione levels and normal cellular regeneration. Taking Curcumin Extreme every day can help detoxify impurities in your body that build up over time.*
Curcumin Extreme also includes 167 mg of broccoli seed extract, a powerful source of sulphoraphane glucosinolates. Sulforaphanes support the normal production of Phase II liver detoxification enzymes, including glutathione synthase, heme-oxygenase and catalase. Sulforaphanes also support gene transcription, the process by which genetic information is copied from DNA to RNA. They also support the body’s natural defense systems. Glutathione is the master antioxidant in the human body, which serves to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. Furthermore, glutathione recycles vitamins C and E, which are also powerful antioxidants.*
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Curcumin (BCM-95®): 400 mg
Scientists have long been aware of the wide array of health benefits from the Indian spice turmeric, which is a source of the active phytochemical curcumin. Until now, curcumin has been known to have poor bioavailability, requiring high doses to promote health. BCM-95 delivers significantly more pharmacologically bioactive curcumin into the blood than other curcumin sources. This new delivery system allows for a variety of health benefits.
How is this possible? Traditional 95% extract focuses strictly on one part of the Turmeric rhizome. This bioactive substance of Turmeric (Curcuma Longa) contains “Curcuminoids” and Curcumin is the most important molecule. Research has shown its tremendous health benefit. Even though Curcumin is the most important molecule, the bioavailability of the regular Turmeric 95% extracts sold on the market is not very good in terms of uptake or sustainability in the blood stream. There are other essential components present in Turmeric Rhizome which have been neglected during the traditional method of manufacturing of Turmeric 95% Extract. BCM-95 represents the natural spectrum of turmeric rhizome. It is 100 percent natural and has been proven to provide optimal bioavailability for synergistic effect. This new method of manufacture offers tremendous value in terms of bioavailability.
Antioxidants have received increased attention, and it’s important to know what nutrients are antioxidants and information about them. One such nutrient is Curcumin. Curcumin is a natural extract from the spice turmeric. Turmeric is derived from the plant Curcuma Longa, a member of the ginger family.
Curcumin is employed mostly as an antioxidant; though it was traditionally used to promote stomach and joint comfort. The immune-balancing activity of curcumin has been demonstrated through multiple mechanisms to support normal COX-2 and NF-KappaB levels in the body.
The neuroprotective properties of curcumin are among the most studied. Curcumin has been designated as a strong candidate for the promotion of neurological health and cognitive function. Curcumin can cross the blood-brain barrier and support the normal uptake of amyloid-beta in the brain. This supports the brain's memory and learning abilities as we age. Another neuroprotective property of curcumin is its ability to promote normal levels of glutathione, superoxide dismutase and catalase in the brain. This can help to maintain the health of neurological tissues.
Curcumin supports the normal production of Phase II liver detoxification enzymes including glutathione synthase, heme-oxygenase and catalase. The liver plays several roles in detoxification: it filters the blood to remove large toxins, synthesizes and secretes bile full of cholesterol and other fat-soluble toxins, and enzymatically disassembles unwanted chemicals. This enzymatic process usually occurs in two steps referred to as phase I and phase II. They promote the body’s natural enzyme antioxidant defense systems and function as a powerful indirect antioxidant. These enzymes promote the body’s normal metabolism of harmful chemicals such as heavy metals, toxins and pollutants into less reactive molecules. Curcumin has also been shown to promote normal hepatic tissue repair.
Broccoli Seed Extract (6% Sulphoraphane Glucosinolates): 167 mg
The health benefits and protective properties of broccoli and other cruciferous vegetables have been well documented over the past 25 years. Broccoli seed extract is a powerful source of sulphoraphane glucosinolates. Sulforaphanes support the normal production of Phase II liver detoxification enzymes including glutathione synthase, heme-oxygenase and catalase. Sulforaphanes promote the body’s natural enzyme antioxidant defense systems and function as a powerful indirect antioxidant. Sulphoraphanes work to support gene transcription, which is the process by which genetic information is copied from DNA to RNA, resulting in a specific protein formation. Conclusively, sulphoraphanes work to support the body’s natural defense systems and to maintain elevated levels of glutathione.
Glutathione is the master antioxidant of the body. It is an important chemical that acts as a powerful antioxidant to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. It also acts to recycle vitamin C and E, which also reduce free radicals. Since glutathione cannot be absorbed intact orally due to gastrointestinal degradation, sulphoraphane supplementation may be the most effective way to increase endogenous glutathione concentration.
Selenium (Selenomethionine): 100 mcg
Selenium is a required cofactor for selenoproteins such as glutathione peroxidase. Selenomethionine is incorporated directly into proteins because selenomethionine cannot be distinguished from methionine during the translation of mRNA into protein. This serves as a storage form of selenium and is liberated upon protein catabolism. Selenium accumulates in the prostate, promoting the health of the prostate. Selenium supports immune function by promoting normal growth and development of T helper cells.
- Araujo, C. and Leon, L. Biological activities of Curcuma longa L. Memorias do Instituto Oswaldo Cruz. 96(5): 723-728, 2001.
- Bhattacharyya, S., et al. Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction. Journal of Biological Chemistry. 282(22): 15954-15964.
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- Funk, J., et al. Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis. Journal of Natural Products. 69(3): 351-355, 2006.
- Gao, X. and Talalay, P. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proceedings of the National Academy of Sciences of the United States of America. 101(28): 10446-10451, 2004.
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- Howells, L., et al. Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines. International Journal of Cancer. 121(1): 175-183, 2007.
- Jagetia, G. and Aggarwal, B. "Spicing up" of the immune system by curcumin. Journal of Clinical Immunology. 27(1): 19-35, 2007.
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- Kurup, V., et al. Immune response modulation by curcumin in a latex allergy model. Clinical and Molecular Allergy. 5: 1, 2007.
- Lim, G., et al. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. Journal of Neuroscience. 21(21): 8370-8377, 2001.
- Lin, J. Molecular targets of curcumin. Advances in Experimental Medicine and Biology. 595: 227-243, 2007.
- Magalska, A., et al. Curcumin induces cell death without oligonucleosomal DNA fragmentation in quiescent and proliferating human CD8+ cells. Acta Biochimica Polonica. 53(3): 531-538, 2006.
- Maheshwari, R., et al. Multiple biological activities of curcumin: a short review. Life Sciences. 78(18): 2081-2087, 2006.
- Mathuria, N. and Verma, R. Ameliorative effect of curcumin on aflatoxin-induced toxicity in DNA, RNA and protein in liver and kidney of mice. Acta Poloniae Pharmaceutica. 64(6): 497-502, 2007.
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- Naik, R., et al. Protection of liver cells from ethanol cytotoxicity by curcumin in liver slice culture in vitro. Journal of Ethnopharmacology. 95(1): 31-37, 2004.
- Nanji, A., et al. Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-kappa B-dependent genes. American Journal of Physiology. 284(2): G321-G327, 2003.
- Ng, T., et al. Curry consumption and cognitive function in the elderly. American Journal of Epidemiology. 164(9): 898-906, 2006.
- Nishinaka, T., et al. Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element. Toxicology Letters. 170(3): 238-247, 2007.
- Noyan-Ashraf, M., et al. Dietary approach to decrease aging-related CNS inflammation. Nutritional Neuroscience. 8(2): 101-110, 2005.
- O’Connell, M. and Rushworth, S. Curcumin: potential for hepatic fibrosis therapy? British Journal of Pharmacology. 153(3): 403-405, 2007.
- Osawa, T. Nephroprotective and hepatoprotective effects of curcuminoids. Advances in Experimental Medicine and Biology. 595: 407-423, 2007.
- Pal, S., et al. Amelioration of immune cell number depletion and potentiation of depressed detoxification system of tumor-bearing mice by curcumin. Cancer Detection and Prevention. 29(5): 470-478, 2005.
- Pari, L. and Amali, D. Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats. Journal of Pharmacy and Pharmaceutical Sciences. 8(1): 115-123, 2005.
- Perkins, S., et al. Chemopreventive efficacy and pharmacokinetics of curcumin in the min/+ mouse, a model of familial adenomatous polyposis. Cancer Epidemiology, Biomarkers, and Prevention. 11(6): 535-540, 2002.
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What is Curcumin?
Curcumin is present in the spice turmeric, frequently used in Indian food. Its chemical makeup is responsible for the yellow coloring of turmeric and is often used specifically to give color to foods. However, it may serve a more important purpose to humans.
Are any side effects associated with Curcumin Extreme?
Side effects are uncommon and are generally limited to mild stomach distress.
What are the potential advantages of taking curcumin?
Curcumin supports liver detoxification activity, promotes normal cellular regeneration and helps maintain healthy glutathione levels. It also supports the body’s natural ability to produce detoxification enzymes and has been shown to be a powerful antioxidant. It promotes neurological health and helps to maintain neurological health as we age. It can also promote free radical protection and a strong immune system.*
Are there any warnings associated with taking Curcumin Extreme?
If you are currently taking warfarin (Coumadin) or other anti-platelet/anti-coagulate, you should not take this product. If you are taking any other prescription drugs or have an ongoing medical condition, you should consult your physician before using this product. Women who are pregnant or breastfeeding should not take this product.
Who should take Curcumin Extreme?
Anyone 18 or over can take Curcumin Extreme, especially those who want to support their normal liver detoxification activity, help maintain their healthy glutathione levels, promote their neurological health and those who want to promote a strong immune system.
What other Market America products work well with Curcumin Extreme?
Curcumin Extreme can be taken in conjunction with Glucosatrin® to support normal COX-2 levels and promote joint comfort. It can also be taken with Cognitin™ to promote normal immune cell-brain (neuron) interactions in order to maintain cognitive health and also to promote neurological health.
Can I take OPC-3® with Curcumin Extreme?
Yes, as long as the directions for use are followed for each product.
I am considering purchasing Curcumin Extreme because of some of the positive effects that I have read about. Should I refrain from taking my medications while taking curcumin or can I take both?
If you are taking any prescription drugs or have an ongoing medical condition, you should consult your physician before using this product. Your physician can properly advise you about the best course of action regarding your prescription medications.
What is the recommended daily serving for Curcumin Extreme?
Take one (1) capsule per day with or without a meal.
Are there any human clinical trials done with Curcumin?
There have been clinical trials performed with curcumin in patients with different diseases. These are mostly pilot studies that are “proof of concept” type. More than 10 trials are now in progress in the United States and other countries.
What is the purpose of the Broccoli Seed Extract contained in this product?
It promotes the liver detoxification activity, and it works to support the body’s natural defense systems and to sustain elevated levels of glutathione.
Can men and women take this product?
Yes. However, women who are pregnant or breastfeeding should not take this product.
Does Curcumin Extreme contain any allergens?
No, the product is free from any allergens such as soy, wheat, gluten or dairy.
When should I start to see/feel the effects of this product? What should I expect?
The antioxidant benefits of Curcumin should be noticeable in about four to six weeks. Please remember that everyone’s body is different, so for some it may take longer to notice the benefits of Curcumin. You should expect to feel better and healthier overall.*
Curcumin Extreme separates itself from the other curcumin products on the market due to its superior bioavailability and absorption. Curcumin Extreme contains BCM-95® along with broccoli seed extract, a powerful source of sulphoraphane glucosinolates, which delivers significantly more bioactive curcumin into the blood than other curcumin sources. The addition of broccoli seed extract also supports normal detoxification activity along with the curcumin. This delivery system allows for a variety of health benefits including supporting overall liver health and free radical protection.*
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Reviewed by 13 customers
Comments about NutriPhysical Curcumin Extreme:
I have had eczema for most of my life. About 2 years ago, I noticed my skin getting itchy and bumps starting to form first on my arm the spreaading to my face and body. I went to my doctor and they gave me a steroid shot and it worked for a week then it came back. I used topical steroids and it seemed to get worse. The doctor suggested to go to UCSF or Stanford to visit a dermatology specialist. I went to a acupuncturist and that did not work. I took a GeneSNP analysis and found that my body could not detox. So, I self diagnosed myself and read about Curcumin Extreme it says it detoxes the liver. So, I ordered a bottle and started to take 2 capsules a day. Almost immediately I had relief! My itching stopped and my skin started to clear up in a week. Now it has been 6 months and I have not used any topical steroids! I am taking this for the rest of my life! This works!
Comments about NutriPhysical Curcumin Extreme:
Use daily and feeling great!
Comments about NutriPhysical Curcumin Extreme:
I love this product because it helps detox my liver. We live in a chemical world and need a product like this to help our liver out.
Comments about NutriPhysical Curcumin Extreme:
The main ingredient in this turmeric is wonderful and powerful antioxidant! Helped me with my skin issues I was going to light therapy for and no longer have to! Would recommend this for anyone even for general maintenance and overall good health!
- Boosts Energy
- Good Value
- Helps Recovery
- Simple To Take
- Great morale booster
Comments about NutriPhysical Curcumin Extreme:
Take one capsule every day.