Isotonix Maximum ORAC

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Isotonix Maximum ORAC

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Product Information

  • An antioxidant for the maintenance of good health
  • Helps in the development and maintenance of bones, cartilage, teeth and gums
  • Helps in connective tissue formation
  • Helps in wound healing
  • A factor in the maintenance of good health

Product Information

Isotonix Maximum ORAC

ORAC refers to Oxygen Radical Absorption Capacity, which is a method for measuring the antioxidant capacities of different foods and how many oxygen radicals a substance can absorb. The use of vitamin E and vitamin C in ORAC supplements contributes to an antioxidant network which offers far more protection than the use of a single agent alone. Antioxidants are natural cell protectors, neutralizing free radicals by pairing an electron to the outermost shell of radical oxygen molecules, rendering them harmless. Antioxidants are nutrients such as vitamins, minerals and enzymes that are capable of counteracting the effects of the physiological process of oxidation in bodily tissues. Antioxidants such as vitamins A, C and E, stabilize free radicals or cause them to decay into harmless atomic structures.

Isotonix Maximum ORAC is an isotonic-capable supplement composed of a powerful blend of blueberries, raspberries, cranberries, elderberries, pomegranate, plum, vitamins C and E. Isotonix Maximum ORAC is intended to be used for its specially selected antioxidant properties. However, it also helps in the development and maintenance of bones, cartilage, teeth and gums, in connective tissue formation and wound healing, and is a factor in the maintenance of good health.

Isotonic, which means “same pressure,” bears the same chemical resemblance to the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.

Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do to in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.

Ingredients

Cranberry Juice Extract
Cranberry is a small evergreen shrub containing dark pink flowers that grows in damp bogs and mountain forests. It blooms from late spring until the end of the summer. The shrub’s small red fruits are produced in the fall. The therapeutic properties of the plant come from the fruit. Cranberries contain proanthocyanidin, which are helpful in promoting a healthy urinary tract and supporting a normal pH of urine. Preliminary evidence suggests that cranberries increase the antioxidant levels of plasma and may help maintain healthy cholesterol levels by providing antioxidant protection of LDL particles. Cranberries have a high ORAC value.

Blueberry Fruit Extract
Blueberries rank highest among many fruits and vegetables for ORAC activity and contain 25-30 different types of anthocyanins. Anthocyanins give blueberries (and other fruits) their rich blue and red colouring, and are powerful flavonoid antioxidants. The mechanism of action surrounding anthocyanins has been studied at the molecular level, demonstrating effects such as promoting cellular health. Blueberries provide large amounts of chlorogenic acid, which is thought to be important in promoting cellular health. Blueberries support the body’s antioxidant network within the body.

Grape Juice Powder
Grapes contain a variety of phenolic compounds, including anthocyanidins, cinnamates and flavan-3-ols (flavonols), which have all been shown to be effective in promoting cardiovascular health. Anthocyanidins are powerful flavonoid antioxidants that contribute to maintaining cellular health. Preliminary evidence suggests that anthocyanidins contribute to supporting healthy capillaries and providing antioxidant protection of LDL particles.

Raspberry Fruit Extract
Raspberries contain significant amounts of polyphenol antioxidants, chemicals linked to promoting endothelial and cardiovascular health. Raspberries are high in fiber, are an excellent source of vitamin C and manganese, a good source of vitamin K and magnesium, and contain some calcium and iron. Raspberries are powerful antioxidants, particularly due to their dense contents of ellagic acid (from ellagotannins), quercetin, gallic acid, anthocyanins, cyanidins, pelargonidins, catechins, kaempferol and salicylic acid. They have a high ORAC value.

Elderberry Fruit Extract
Elderberries contain the flavonoids rutin, isoquertin and hyperoside, as well as anthocyan glycosides, an essential oil. Elderberries have historically been used to make elderberry wine, elder brandy, and sambuca, a popular cordial. Elderberries have a high ORAC value, and contribute to promoting a comprehensive antioxidant network.

Pomegranate Fruit Extract
One pomegranate delivers 40 percent of an adult's daily vitamin C requirement, and is a rich source of folic acid and antioxidants. Pomegranates are high in polyphenols. The most abundant polyphenols in pomegranate are hydrolysable tannins, particularly punicalagins, which research has shown to be the antioxidant responsible for the free-radical scavenging ability of pomegranate juice.

Plum Powder
Plums contain several powerful antioxidants and they have a high ORAC content. They are rich sources of many essential vitamins and minerals. They are also rich in dietary fiber, sorbitol and isatin. They have been commonly used to promote digestive health but also contribute to a comprehensive antioxidant network.

Vitamin C (Ascorbic Acid)
Vitamin C is found in peppers (sweet, green, red, hot red and green chili), citrus fruits, brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries. Nuts and grains contain small amounts of vitamin C. It is important to note that cooking destroys vitamin C activity.

Vitamin C is integral in supporting a healthy immune system, promoting cardiovascular health, maintaining healthy cholesterol levels and providing an antioxidant defense. The body does not manufacture vitamin C on its own, nor does it store it. Therefore, vitamin C must be acquired through diet and supplementation.

Vitamin E
Vitamin E is a collective term for a group of compounds from the tocopherol and tocotrienol chemical groups. The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amounts of vitamin E and there are trace amounts in corn oil and soybean oil. For those individuals watching their dietary fat consumption vitamin E intake is likely to be low due to a reduced intake of foods with high fat content. The main health benefit of supplemental vitamin E comes from its immune-boosting antioxidant activity. It is also known to provide protection for the cardiovascular system. Vitamin E is one of the most powerful fat-soluble antioxidants in the body which help to protect cell membranes from free radicals. The combination of vitamins C and E together forms an antioxidant network, allowing the vitamins to engage (synergistically) in each others’ regeneration from the spent state back to the active antioxidant state so that they can continue neutralizing free radicals.

Science

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  • Ames, BN, et al.  Oxidants, antioxidants, and the degenerative diseases of aging.  Proc Natl Acad Sci USA 90:7915-7922, 1993.
  • Andres-Lacueva, C., et al. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr Neurosci. 8:111-20, 2005.
  • Aviram, M., et al.  Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice.  American Journal of Clinical Nutrition.  71:1062-1076, 2000.
  • Aviram, M., et al.  Pomegranate juice flavonoids inhibit low-density lipoprotein oxidation and cardiovascular diseases: studies in atherosclerotic mice and in humans.  Drugs Exp Clin Res.  28:49-62, 2002.
  • Badmaev, V., et al. Piperine derived from black pepper increases the plasma levels of coenzyme Q10 following oral supplementation. J Nutr Biochem. 11:109-13, 2000.
  • Bagchi, D, et al.  Cellular protection with proanthocyanidins derived from grape seed.  Ann NY Acad Sci 957:260-70, 2002.
  • Bagchi, D, et al.  Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention.  Toxicology 148: 187-97, 2000.
  • Bagchi, D, et al.  Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro.  Res Commun Mol Pathol Pharmacol 95:179-89, 1997.
  • Bagchi, D., et al. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry. 69:95-102, 2004.
  • Bagchi, D., et al. Safety and whole-body antioxidant potential of a novel anthocyanin-rich formulation of edible berries. Mol Cell Biochem. 281:197-209, 2006.
  • Berry, E., et al. Synergism between vitamins E and C: biological implications for future research. Int J Cancer. 83:288, 1999.
  • Cao, G., et al. Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables. Am J Clin Nutr. 68:1081-7, 1998.
  • Cao, G., et al. Oxygen-radical absorbance capacity assay for antioxidants. Free Radical Biology and Medicine. 14: 303-11, 1993.
  • Casadesus, G., et al. Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutr Neurosci. 7:309-16, 2004.
  • Chu, Y., et al. Cranberries inhibit LDL oxidation and induce LDL receptor expression in hepatocytes. Life Sci. 77:1892-901, 2005.
  • Chun, O., et al. Superoxide radical scavenging activity of the major polyphenols in fresh plums. J Agric Food Chem. 51:8067-72, 2003.
  • Drew B, Leeuwenburgh C.  Aging and the role of reactive nitrogen species.  Ann NY Acad Sci 959:66-81, 2002.
  • Esmaillzadeh, A., et al.  Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia.  J Med Food. 7(3):305-308, 2004.
  • Faria, A., et al. Antioxidant properties of prepared blueberry (Vaccinium myrtillus) extracts. J Agric Food Chem. 53:6896-902, 2005.
  • Frei, B., et al.  Ascorbate is an outstanding antioxidant in human blood plasma.  Proceedings of the National Academy of Sciences USA 86(16):6377-6381, 1989.
  • Galli, R., et al. Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection. Neurobiol Aging. 27:344-50, 2006.
  • Galli, R., et al. Fruit polyphenolics and brain aging: nutritional interventions targeting age-related neuronal and behavioral deficits. Ann N Y Acad Sci. 959:128-32, 2002.  Review.
  • Gibson, L, et al.  Effectiveness of cranberry juice in preventing urinary tract infections in long-term care facility patients.  J Naturopathic Med 2:45-47, 1991.
  • Graham DY, Smith JL, Bouvet, AA.  What happens to tablets in the stomach.  J Pharm Sci 79:420-24, 1990.
  • Halpern, MJ, et al.  Red wine polyphenols and inhibition of platelet aggregation: possible mechanisms, and potential use in health promotion and disease prevention.  J Int Med Res 26:171-80, 1998.
  • Halvorsen, B., et al. A systematic screening of total antioxidants in dietary plants. J Nutr. 132:461-71, 2002.
  • Hamilton, I., et al.  Interactions between vitamins C and E in human subjects.  British Journal of Nutrition.  84:261-267, 2000.
  • Havsteen B.  Flavonoids, a class of natural products of high pharmacological potency.  Biochem Pharm 32:1141-48, 1983.
  • Hope Smith, S., et al. Antimutagenic activity of berry extracts. J Med Food. 7:450-5, 2004.
  • Hou, D., et al. Potential mechanisms of cancer chemoprevention by anthocyanins. Curr Mol Med. 3:149-59 2003.  Review.
  • Joseph, J., et al. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci. 19:8114-21, 1999.
  • Joseph, J., et al. Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds. Am J Clin Nutr. 81(1 Suppl):313S-316S, 2005. . Review.
  • Kamal-Eldin, A., et al. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids. 31: 671-701, 1996.
  • Kay, C., et al. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 88:389-98, 2002.
  • Kehrer JP.  Free radicals as mediators of tissue injury and disease.  Crit Rev Toxicol 23:21-48, 1993.
  • Koch R. Comparative study of Venostatin and Pycnogenol in chronic venous insufficiency.  Phytother Res 16:S1-5, 2002.
  • Koparker AD, Augsburger LL, Shangraw RF.  Intrinsic dissolution rates of tablet fillers and binders and their influence on the dissolution of drugs from tablet formulations.  Pharm Res 7:80-85, 1990.
  • Lambert, J., et al. Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice. J Nutr. 134:1948-52, 2004.
  • Lau, F., et al. The beneficial effects of fruit polyphenols on brain aging. Neurobiol Aging. 26 Suppl 1:128-32, 2005.
  • Liu, M., et al. Antioxidant and antiproliferative activities of raspberries. J Agric Food Chem. 50:2926-30, 2002.
  • Maatta, K., et al. Phenolic compounds in berries of black, red, green, and white currants (Ribes sp.). Antioxid Redox Signal. 3:981-93, 2001.
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  • Mazza, G., et al.  Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 50:7731-7, 2002.
  • Monograph. Sambucus nigra (elderberry). Altern Med Rev. 10:51-4, 2005.
  • Murkovic, M., et al. Effects of elderberry juice on fasting and postprandial serum lipids and low-density lipoprotein oxidation in healthy volunteers: a randomized, double-blind, placebo-controlled study. Eur J Clin Nutr. 58:244-9, 2004.
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  • Ofek I, Goldhar J, Zafriri D, Lis H, Sharon N.  Anti-Escherichia coli adhesion activity of cranberry and blueberry juices. New England J Med 324:1599, 1991.
  • Packer, L., et al.  Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling.  Journal of Nutrition.  131:369S-373S, 2001.
  • Qureshi, A, et al.  Response of hypercholesterolemic subjects to administration of tocotrienols.  Lipids 30:1171-77, 1995.
  • Reed, J. Cranberry flavonoids, atherosclerosis and cardiovascular health. Crit Rev Food Sci Nutr. 42(3 Suppl):301-16, 2002.  Review.
  • Rimbach G, Virgili F, Park YC, Packer L.  Effect of procyanidins from Pinus maritime on glutathione levels in endothelial cells challenged by 3-morpholinosydnonimine or activated macrophages.  Redox Rep 4:171-77, 1999. 
  • Roy, S., et al. Anti-angiogenic property of edible berries. Free Radical Research. 36: 1023-31, 2002.
  • Ruel, G., et al. Changes in plasma antioxidant capacity and oxidized low-density lipoprotein levels in men after short-term cranberry juice consumption. Metabolism. 54:856-61, 2005.
  • Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 64:353-6, 1998.
  • Sobota AE.  Inhibition of bacterial adherence by cranberry juice: potential use for the treatment of urinary tract infactions.  J Urology 131:1013-1016, 1984.
  • Soloway MS, Smith RA.  J Am Med Assoc 260:1465, 1988.
  • Stein, J., et al. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation 100: 1050-5, 1999.
  • Tomco, A, et al.  Antioxidant effects of tocotrienol in patients with hyperlipidemia and carotid stenosis.  Lipids 30: 1179-83, 1995.
  • Vuorela, S., et al. Preclinical evaluation of grapeseed, raspberry, and pine bark phenolics for health related effects. J Agric Food Chem. 53:5922-31, 2005.
  • Wang, R., et al. Bioactive compounds from the seeds of Punica granatum (pomegranate). J Nat Prod. 67:2096-8, 2004.
  • Weiss, E., et al.  Cranberry juice constituents affect influenza virus adhesion and infectivity.  Antiviral Res.  66:9-12, 2005.
  • Wilson, T., et al.  Cranberry extract inhibits low density lipoprotein oxidation.  Life Sciences.  62:381-386, 1998.
  • Youdim, K. A., et al.  Incorporation of elderberry anthocyanins by endothelial cells increases protection against oxidative stress.  Free Radic Biol Medicine.  29:51-60, 2000.
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FAQ

What is an antioxidant? 
Antioxidant means ‘against oxidation’. Antioxidants work to protect lipids from peroxidation by radical elements. Antioxidants are effective because they give up their own electrons to free radicals thereby stabilizing the radical. When a free radical gains the electron from an antioxidant, the chain reaction of oxidation is broken.


Where do free radicals come from?
Simply breathing (respiration), metabolizing food and generating ATP to fuel enzymatic reactions can create free radicals. Free radicals are created by the following: eating high fat foods, processed foods, food preservatives, ionizing radiation (UV, gamma, X-rays), exercise, stress, pollution, chlorine in drinking water, and tobacco smoke. Maximum ORAC contributes to the body’s ability to counteract oxidation by increasing the levels of antioxidants in the bloodstream, and protecting the other antioxidants that are acquired from our diets and promoting their full antioxidant activity in some cases.


I already take an antioxidant supplement with vitamins A, C, and E. Is there an advantage in taking supplements in isotonic form?
Yes. When you ingest food, drink, beverages or most nutritional supplements, the stomach must secrete diluting juices, enzymes, hydrochloric acid and at least one vitamin-binding protein to begin the process of digestion. This process can take about 40 minutes, depending on the size of the meal, and it requires both time and energy. The advantage of using Isotonix products are that they are delivered directly into the small intestine nutritionally concentrated. This maximizes the opportunity for absorption of the nutrients across the cell membranes. 


Isotonix products, such as the Maximum ORAC, are usually taken on an empty stomach, which considerably shortens the transit time through the body. Since the transit time is shortened, it minimizes the chance that vital micronutrients will be trapped in the body by fats, fibers and tannins, or even inactivated by a highly acidic pH level, which can all lead to neutralization in the nutritional value. The solution flows into the small intestine, where it mixes with pancreatic digestive juices, which adds sodium bicarbonate to adjust the pH to neutral, and in so doing, maximizes the potential uptake of nutrients.

What is the difference in taking an isotonic formula as compared to taking traditional tablets?
Isotonic solutions offer the fastest and most efficient delivery of all oral forms of supplementation. The nutrients in the solutions are quickly and effectively absorbed into the bloodstream, and do not linger in the stomach causing gastrointestinal discomfort. Isotonix products are not encapsulated, so there is no need for them to contain fillers, binders, coatings, lubricants, disintegrators or artificial colouring like there can be in traditional nutrient supplements. 


What does ORAC stand for?
Oxygen Radical Absorption Capacity (ORAC) is an assay that measures the antioxidant activity of a substance. ORAC assays measure how many oxygen radicals a substance can absorb. The higher its ORAC score, the better it is at helping our bodies destroy free radicals.

Fruits and vegetables are well known for their antioxidant power. Each piece of fruit and every serving of vegetable we eat has an ORAC score. This score measures a food's free radical-fighting capabilities. The higher the score, the better a food is at helping our bodies destroy free radicals. But high-ORAC foods - berries and spices, most notably - are becoming less and less frequent in keeping with our modern, on-the-go diets. That is why it is important to supplement your body's free radical fighting ability with Isotonix Maximum ORAC, a comprehensive antioxidant network of fruit extracts and antioxidant-rich vitamins.

REVIEW SNAPSHOT®

by PowerReviews
Isotonix® Maximum ORAC Formula
 
4.9

(based on 22 reviews)

Ratings Distribution

  • 5 Stars

     

    (20)

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    (2)

  • 3 Stars

     

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100%

of respondents would recommend this to a friend.

Pros

  • Simple to take (15)
  • Acts quickly (13)
  • Good taste (13)
  • Produces results (13)
  • Boosts energy (3)

Cons

    Best Uses

    • Daily use (14)
    • Women (10)
    • Men (7)
    • Older people (6)
    • Daily prevention (3)
      • Reviewer Profile:
      • Health conscious (9), First time user (8), Regular user (7)

    Reviewed by 22 customers

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    5.0

    ORAC - Fighting Free Radicals

    By Jon the gardener

    from Iron Range, Minnesota

    About Me Keep In Shape, Love Feeling Good, Love Gardening

    SHOP CONSULTANT

    Pros

    • Easy To Take
    • Effective
    • Good Value
    • Great Product
    • Nutritional
    • Tastes Good
    • Use Bottle Top Insert

    Cons

      Best Uses

      • As A Snack
      • Everyday Use
      • Meal Replacement
      • Men
      • Old Or Young
      • Women

      Comments about Isotonix® Maximum ORAC Formula:

      The ORAC is easy to use. We insert into the top of the bottles a pour spout that has a small opening and the product pours easily
      into the container (we use the small bottles) that are available for
      Isotonix (with the Isotonix label on it) and blend a mix of products
      into the one little bottle. * Great for traveling * We usually mix enough for a full week because of our work and traveling.
      We recommend this to anyone who doesn't feel good or needs an extra boost of energy and wellness!
      This product is added as we see a need for it...and we love what it does inside our bodies. Fight free radicals.

       
      5.0

      can't go a day without this product

      By ConnieC

      from USA

      Comments about Isotonix® Maximum ORAC Formula:

      I like to mix my ORAC with my OPC-3 every morning. I take 2 caps of ORAC and 4 caps of OPC to fight free-radical damage to my body. I am in my mid 30's and would like to slow down the aging process as much as possible. Drinking anti-oxidants like ORAC will definitely help me maintain a healthier lifestyle. Thank you Shop.com for the high quality products at affordable prices.

      (0 of 1 customers found this review helpful)

       
      5.0

      I use this product ...

      By MarilynR

      from USA

      Comments about Isotonix® Maximum ORAC Formula:

      I use this product religiously every day and I take 4 measures at first I did not find any change but then you have to give supplements a chance to work, in about a weeks time I felt great. My defining moment was when I went out of state to visit my family, I left it behind and I was feeling so good at the time and not having it a few times I felt sluggish and really missed the taste of berry every morning. I have great faith in these products.

      (1 of 2 customers found this review helpful)

       
      5.0

      "I would buy this product again and agai

      By Lulu

      from Milford, CT

      About Me First Time User

      Verified Buyer

      Pros

      • Boosts Energy
      • Good Value
      • Simple To Take

      Cons

      • None so far

      Best Uses

      • Daily Prevention

      Comments about Isotonix® Maximum ORAC Formula:

      I use this product religiously every day and I take 4 measures at first I did not find any change but then you have to give supplements a chance to work, in about a weeks time I felt great. My defining moment was when I went out of state to visit my family, I left it behind and I was feeling so good at the time and not having it a few times I felt sluggish and really missed the taste of berry every morning.

      I have great faith in these products.

       
      5.0

      Its the best product I every had.

      By Tee

      from Indianapolis,IN

      About Me First Time User

      Verified Buyer

      Pros

      • Simple To Take

      Cons

        Best Uses

          Comments about Isotonix® Maximum ORAC Formula:

          Its best to use this product in the morning with out anything on your stomach. It makes me look younger, at first I didn't notice nothing different but when I go in public people would compliment my skin and said my face was glowing. As time went on I started to notice my skin was getting smoother. The product worked for me quickly and I been using for a month now. I just love the product, I will be using it for along time.

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