- Promotes optimal immune functions
- Provides antioxidant protection
- Promotes normal regulation of heart functions
- Promotes cognitive health
- Reduces the inflammatory response
- Promotes skeleton, muscle and skin health
- Helps maintain healthy cholesterol levels
Isotonix Vitamin C
Vitamin C is a super antioxidant well known for promoting a healthy immune system, providing cardiovascular support, reducing free radical production and free radical damage, and maintaining good cognitive health and performance.
Since we don't naturally produce vitamin C, it is essential to include vitamin C-rich foods on a regular, if not daily basis. To complement the vitamin C in fruits and vegetables, you should look at using a quality vitamin C supplement, like Isotonix Vitamin C.
While the amounts of vitamin C in fruits and vegetables is only a fraction of that recommended on a daily basis, Isotonix Vitamin C contains over 500 percent of the Recommended Daily Value of vitamin C - an amount greater than many vitamin C supplements on the market today. Plus, no other supplements for immune support on the market can boast the revolutionary Isotonix Delivery System.
Vitamin C metabolism is crucial, as this nutrient is essential for human health and life. Whereas other vitamin C supplements include binders and fillers that prolong the utilization of this vital nutrient, Isotonix Vitamin C delivers its vitamin C benefits quickly and effectively, meaning faster and maximum results for your body.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Vitamin C plays a role in a variety of metabolic functions. In addition to promoting optimal immune function, it also promotes skeletal, muscle and skin health. Only Isotonix offers Vitamin C using isotonic delivery, providing maximum nutrient absorption.
Must have this season
Without a doubt its a must have this season! If you have blood in your veins and breath air, then its a no brainer! Defiantly don't want to get sick!
simple way to help immune system
Most useful at times when I am just starting to feel a cold coming on - or when I have been super busy and want to avoid stress to my immune system
A must have for every day health
People look down on vitamin C too much, because we can get them easily. But people don't realize half the time that we also lose it very easily. This makes vitamin C very important to consume in moderate amount consistently. A capful of Vitamin C is equivalent to an orange, or probably several. While you may consider eating oranges to get your vitamin C, it's mostly not absorbed into the system anyhow, and you lose out on absorbing them.
I've always had trouble taking pills. Since this product is liquid, it's easy to swallow and digest. I usually take it at night since i tend to forget to take my vitamins in the morning. Not to mention, it does not upset my stomach as most other vitamins did.
Vitamin C (Ascorbic Acid) (500 mg)
Around 90 percent of vitamin C in the typical diet comes from fresh fruits and vegetables. Peppers - sweet green, red, hot red and green chili peppers - are especially rich in vitamin C. Other good sources include citrus fruits and juices, brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach and strawberries. It is important to note that cooking destroys vitamin C activity.
Vitamin C, justifiably so, has become the world's most popular vitamin. The reasoning behind this vitamin's grand reputation is at once multifaceted as well as amazing. The bodily functions promoted by this vitamin create an extensive list.
Ascorbic acid is best known for its antioxidant properties. Ascorbic acid may be the most important water-soluble antioxidant in the body.
The capacity of vitamin C to support the immune system seems to be common knowledge. As a way to prevent and or reduce the symptoms associated with the common cold, over 100 studies have been conducted. A number of small, targeted studies, in subjects under heavy acute physical stress, show that vitamin C cuts common cold occurrence in half. At least three controlled studies have shown an 80 percent reduction in the incidence of pneumonia among vitamin C users. In one large study (over 700 students), vitamin C (1000 mg per hour for the first six hours followed by 3000 mg per day), reduced cold and flu symptoms by 85 percent. In most cases, it appears that while the most important and dramatic preventive effects of vitamin C supplementation will be experienced by individuals with low vitamin C intakes, those with average intake from foods will also benefit from supplementation. In support of an elevated vitamin C intake, an expert scientific panel recently recommended increasing the current RDA for vitamin C from 60mg to at least 100-200mg per day.
Next, Vitamin C may promote normal pulmonary health. Part of the protective action of vitamin C appears to be due to its antioxidant properties. Finally, some studies suggest that vitamin C supplementation will help to maintain healthy vision.
Vitamin C helps support cardiovascular health in a few different ways. It assists in promoting normal levels of cholesterol and normal blood pressure and promotes normal platelet activity. It also promotes healthy triglyceride levels. Vitamin C protects against LDL peroxidation by scavenging free radicals. Vitamin C helps maintain endothelial cell function by promoting the synthesis of nitric oxide (also known as NO and EDRF for endothelium-derived relaxing factor).
Vitamin C helps preserve intracellular reduced glutathione concentrations. This activity helps maintain nitric oxide levels and potentiates its vasoactive effects, helping to maintain the integrity of blood vessels.
Vitamin C promotes normal modulation of prostaglandin synthesis, which in turn promotes normal vasodilatory activity. It helps maintain nitric oxide levels and supports its ability to preserve the integrity of the blood vessels. There is an indication that vitamin C supports endothelial-dependent vasodilation.
Vitamin C plays a crucial role in maintaining healthy connective tissues including collagen, elastin, fibronectin, proteoglycans, bone matrix and elastin-associated fibrillin. Also, a lack of vitamin C can cause general fatigue. Vitamin C also helps moderate healthy iron absorption, transport and storage. It promotes the normal intestinal absorption of iron.*
Beta Carotene (Vitamin A) (800 IU)
Vitamin A is a fat-soluble vitamin that is part of a family of compounds including retinol, retinal and beta-carotene. Beta-carotene is also known as pro-vitamin A because it can be converted into vitamin A. The best sources of vitamin A include organ meats (such as liver and kidney) egg yolks, butter, carrot juice, squash, sweet potatoes, spinach, peaches, fortified dairy products (such as milk and some margarines) and cod liver oil.
Vitamin A has exhibited anti-aging and antioxidant activities. Vitamin A helps to maintain vision. It promotes normal bone growth and also contributes to a healthy immune system. Vitamin A supports normal epithelial differentiation, growth, reproduction, pattern formation during embryogenesis, bone development, hematopoiesis and brain development. Children are particularly susceptible to the effects of vitamin A deficiency.
Potassium (Bicarbonate) (99 mg)
Foods rich in potassium include fresh vegetables and fruits such as bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery.
Potassium is an essential macro-mineral that helps to maintain fluid balance. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, it promotes the normal transmission of nerve impulses, the normal contraction of cardiac, skeletal and smooth muscle, the normal production of energy, the normal synthesis of nucleic acids, the maintenance of intracellular tonicity and the maintenance of normal blood pressure. Potassium promotes muscle relaxation, and supports normal insulin release. It also promotes normal glycogen and protein synthesis. Potassium is an electrolyte that promotes proper heartbeat, and it is important in supporting the normal release of energy from protein, fat and carbohydrates during metabolism.*
Potassium also promotes the normal regulation of water balance. Potassium promotes the normal elimination of wastes and generally contributes to a sense of well being. Potassium is stored in the muscles.*
Some symptoms of potassium deficiency include poor circulation, earaches, inability to sleep, muscle weakness and water retention.
Sodium and potassium are two of the most important ions in helping the body maintain the homeostatic equilibrium of fluids.*
- Addison WLT, The use of sodium chloride, potassium chloride, sodium bromide and potassium bromide in cases of arterial hypertension which are amenable to potassium chloride. Can Med Assoc J. 1928; 18:281-285.
- Allende LM, Corell A, Madrono A, Gongora R, Rodriguez-Gallego C, Lopez-Goyanes A, Rosal M, Arnaiz-Villena A. Retinol (vitamin A) is a cofactor in CD3-induced human T-lymphocyte activation. Immunology. 1997 Mar;90(3):388-96
- Amin A. Berberine Sulfate antimicrobial activity, bioassay and mode of action. Can J Microbiol 1969; 15.
- Awad AB, Fink CB. Phytosterols as anticancer dietary components: Evidence and mechanism of action. J Nutr 2000; 130:2127-2130.
- Bates CJ. Vitamin A. Lancet. 1995; 345:31-35.
- Bauer R, Jurcic K, Puhlmann J, Wagner H. Immunological in-vivo and in-vitro examinations of echinacea extracts. Arzneimittel-Forsch 1988;38:276-81.
- Bauer R. Echinacea: Biological Effects and Active Principles. Phytomedicines of Europe: Chemistry and Biological Activity. Washington, D.C.: American Chemical Society 1998:140-57.
- Bendich A. Antioxidant vitamins and human immune responses. Vitam Horm 1996;52:35-62:35-62.
- Benedikt H. Arabinogalactans: New immune boosting fiber. Natural Pharmacy 1999;3(6).
- Bodinet C, Beuscher N. Antiviral and immunological activity of glycoproteins from echinacea purpurea radix. Planta Medica 1992;57.
- Bouic P, Lamprecht J, Clark A, et al. Beta-sitosterol and beta-sitosterol glucoside as immune modulators: their clinical applications in infectious diseases. April 18, 2000. Unpublished Work.
- Braunig B. Echinacea purpurea radix for strengthening the immune response in flu-like infections. Zeitschrift fur Phytotherapie 1992;13:7-13.
- Brody S, Preut R, Schommer K, Schurmeyer TH. A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress. Psychopharmacology (Berl) 2002;159:319-24.
- Cappuccio FP, MacGregor GA. Does potassium supplementation lower blood pressure? A meta-analysis of published trials. J Hypertens. 1991; 9:465-473.
- Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions? FASEBJ. 1999; 13:1007-1024.
- Carr AC, Tijerina T, Frei B. Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein. Biochem J. 2000; 346 Pt 2:491-496.
- Chandra RK. 1990 McCollum Award lecture. Nutrition and immunity: lessons from the past and new insights into the future. Am J Clin Nutr 1991;53:1087-101.
- Anon., Chapter 5-Vitamin C. In: Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. A Report of the Panel on Dietary Antioxidants and Related Compounds, Subcommittees on Upper Reference Levels of Nutrients and Interpretation and Uses of Dietary Reference Intakes, and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Food and Nutrition Board, Institute of Medicine. National Academy Press:Washington, DC, 2000, pp. 95-185.
- Cooke MS, Evans MD, Podmore ID, et al. Novel repair action of vitamin C upon in vivo oxidative DNA damage. FEBS Lett. 1998; 439:363-367.
- Cosgrove J. Immune support-granting immunity. New ingredients join familiar favorites in the charge for immune enhancement. Nutritional Outlook 2000;41:4.
- Daudu PA, Kelley DS, Taylor PC, Burri BJ, Wu MM. Effect of a low beta-carotene diet on the immune functions of adult women. Am J Clin Nutr. 1994 Dec;60(6):969-72.
- Anon., Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, D.C.: National Academy Press; 2000.
- Duffy SJ, Gokce N, Holbrook M, et al. Treatment of hypertension with ascorbic acid. Lancet. 1999; 354:2048-2049.
- Elitsur Y, Neace C, Liu X, Dosescu J, Moshier JA. Vitamin A and retinoic acids immunomodulation on human gut lymphocytes. Immunopharmacology. 1997 Jan;35(3):247-53.
- Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology. 1992; 3:194-202.
- Fang J, Madhavan S, Alderman MH. Dietary potassium intake and stroke mortality. Stroke. 2000; 31:1532-1537.
- Fay MJ, Bush MJ, Verlangieri AJ. Effect of aldonic acids on the uptake of ascorbic acid by 3T3 mouse fibroblasts and human T lymphoma cells. Gen Pharmacol. 1994; 25:1465-1469.
- Fay MJ, Verlangieri AJ. Stimulatory action of calcium L-threonate on ascorbic acid uptake by a human T-lymphoma cell line. Life Sci. 1991; 49:1377-1381.
- Friedman PA, Zeidel ML. Victory at C. Nature Med. 1999; 5:620-621.
- Futoryan T, Gilchrest BA. Retinoids and the skin. Nutr Rev. 1994; 52:299-310.
- Gamble J, Grewal PS, Gartside IB. Vitamin C modifies the cardiovascular and microvascular responses to cigarette smoke inhalation in man. Clin Science. 2000; 98:455-460.
- Gromova EG, Sviridova SP, Kushlinskii NE, et al. Regulation of the indices of neuroendocrine status in surgical patients with lung cancer using optimal doses of ascorbic acid. Anesteziol Reanimatol 1990;5:71-4 [in Russian].
- Halliwell B. Vitamin C: poison, prophylactic or panacea? Trends Biochem Sci. 1999; 24:255-259.
- Harakeh S, Jariwalla RJ, Pauling L. Suppression of human immunodeficiency virus replication by ascorbate in chronically and acutely infected cells. Proc Natl Acad SciUSA. 1990; 87:7245-7249.
- Harding JJ, Hassett PC, Rixon KC, et al. Sugars including erythronic and threonic acids in the human aqueous humor. Curr Eye Res. 1999; 19:131-136.
- Hemila H, Douglas RM. Vitamin C and acute respiratory infections. Int J Tuberc Lung Dis. 1999; 3:756-761.
- Hemilä H. Vitamin C intake and susceptibility to pneumonia. Pediatr Infect Dis J 1997;16:836-7.
- Hemila H. Vitamin C intake and susceptibility to the common cold. British Journal of Nutrition 1997;77:59-72.
- Hermans JJ, Fischer MA, Schiffers PM, Struijker-Boudier HA. High dietary potassium chloride intake augments rat renal mineralocorticoid receptor selectivity via 11beta-hydroxysteroid dehydrogenase. Biochim Biophys Acta. 1999; 1472:537-549.
- Hermansen K. Diet, blood pressure and hypertension. Br J Nutr. 2000; 83 Supp1:S113-S119.
- Hodison T, Socaciu C, Ropan I, Neamtu G. Carotenoid composition of Rosa canina fruits determined by thin-layer chromatography and high performance liquid chromatography. J Pharmaceut Biomed Anal. 1997; 16:521-528.
- Hornero-Méndez D, Minguez-Mosquera MI. Carotenoid pigments in Rosa mosqueta hips, an alternative carotenoid source for foods. J Agric Food Chem. 2000; 48:825-828.
- Hunt C, Chakravorty NK, Annan G, Habibzadeh N, Schorah CJ. The clinical effects of vitamin C supplementation in elderly hospitalized patients with acute respiratory infections. Int J Vitam Nutr Res 1994;64:212-9.
- Hwang J, Peterson H, Hodis HN, et al. Ascorbic acid enhances 17 beta-estradiol-mediated inhibition of oxidized low density lipoprotein formation. Atherosclerosis. 2000; 150:275-284.
- Ip C. Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats. J Nat Cancer Inst. 1986; 77:299-303.
- Jacob RA. Vitamin C In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: William and Wilkins; 1999:467-483.
- Jacobson SG, Cideciyan AV, Regunath G, et al. Night blindness in Sorsby's fundus dystrophy reversed by vitamin A. Nature Gen. 1995; 11:27-32.
- Jarosz M, Dzieniszewski J, Dabrowska-Ufniarz E, et al. Effects of high dose vitamin C treatment on Helicobacter pylori ingestion and total vitamin C concentration in gastric juice. Eur J Cancer Prev. 1998; 7:449-454.
- Jayachandran M, Panneerselvam C. Cellular immune responses to vitamin C supplementation in aging humans assessed by the in vitro leucocyte migration inhibition test. Med Sci Res 1998;26:227-30.
- Jin L, ChaoL, Chao J. Potassium supplement upregulates the expression of renal kalikrein and bradykinin B2 receptor in SHR. Am J Physiol. 1999; 276:F476-F484.
- Jones PJH, MacDougall DE, Ntanios F, Vanstone CA. Dietary phytosterols as cholesterol-lowering agents in humans. Can J Physiol Pharmacol 1997;75(3):217-227.
- Kelly GS. Larch arabinogalactan: clinical relevance of a novel immune-enhancing polysaccharide. Altern Med Rev 1999;4:96-103.
- Khaw K-T, Barrett-Conner E. Dietary potassium and stroke-associated mortality. N Engl J Med. 1987; 316:235-240.
- Krishna GG, Miller E, Kapoor S. Increased blood pressure during potassium depletion in normotensive men. N Eng J Med. 1989; 320:1177-1182.
- Kurbacher CM, Wagner U, Kolster B, et al. Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitro. Cancer Letters. 1996; 103:183-189.
- Kwaselow A, Rowe M, Sears-Ewald D, Ownby D. Rose hips: a new occupational allergen. J Allergy Clin Immunol. 1990; 85:704-708.Lykkesfeldt J, Christen S, Wallock LM, et al. Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary intakes. Am J Clin Nutr. 2000; 71:530-536.
- Lee M-O, Han S-Y, Jiang S, et al. Differential effects of retinoic acid on growth and apoptosis in human colon cancer cell lines associated with the induction of retinoic acid receptor beta. Biochem Pharmacol. 2000; 59:485-496.
- Lesourd BM, Mazari L, Ferry M. The role of nutrition in immunity in the aged. Nutr Rev 1998;56:S113-S125.
- McCabe RD, Backarich MA, Srivastava K, Young DB. Potassium inhibits free radical formation. Hypertension. 1994; 24:77-82.
- McCabe RD, Young DB. Potassium inhibits cultural vascular smooth muscle proliferation. Am J Hypertens. 1994; 7:346-350.
- Moertel CG, Fleming TR, Creagan ET, et al. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who had no prior chemotherapy. A randomized double-blind comparison. N Engl J Med. 1985; 312:137-141.
- Mowat C, Carswell A, Wirz A, McColl KEL. Omeprazole and dietary nitrate independently affect levels of vitamin C and nitrite in gastric juice. Gastroenterology. 1999; 116:813-822.
- Ness AR, Chee D, Elliot P. Vitamin C and blood pressure - an overview. J Hum Hypertens. 1997; 11:343-350.
- Panda K, Chattopadhyay R, Ghosh MK, et al. Vitamin C prevents cigarette smoke induced oxidative damage of proteins and increased proteolysis. Free Rad Biol Med. 1999; 27:1064-1079.
- Park JB, Levine M. Intracellular accumulation of ascorbic acid is inhibited by flavonoids via blocking of dehydroascorbic acid and ascorbic acid uptakes in HL-60, U937 and Jurkat cells. J Nutr. 2000; 130:1297-1302.
- Pauling L. Evolution and the need for ascorbic acid. Proc Natl Acad SciUSA. 1970; 67:1643-1648.
- Pauling L. The significance of the evidence about ascorbic acid and the common cold. Proc Natl Acad SciUSA. 1971; 68:2678-2681.
- Penn ND, Purkins L, Kelleher J, Heatley RV, Mascie-Taylor BH, Belfield PW. The effect of dietary supplementation with vitamins A, C and E on cell- mediated immune function in elderly long-stay patients: a randomized controlled trial. Age Ageing 1991;20(3):169-174.
- Peters EM, Anderson R, Nieman DC, et al. Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running. Int J Sports Med 2001;22:537-43.
- Peters EM, Anderson R, Theron AJ. Attenuation of increase in circulating cortisol and enhancement of the acute phase protein response in vitamin C-supplemented ultramarathoners. Int J Sports Med 2001;22:120-6.
- Podmore ID, Griffiths HR, Herbert KE, et al. Vitamin C exhibits pro-oxidant effects. Nature. 1998; 392:559.
- Raitakari OT, Adams MR, McCredie RJ, et al. Oral vitamin C and endothelial function in smokers: short-term improvement, but no sustained beneficial effect. J Amer Coll Cardiol. 2000; 35:1616-1621.
- Rehman A, Collis CS, Yang M, et al. The effects of iron and vitamin C co-supplementation on oxidative damage to DNA in healthy volunteers. Biochem Biophys Res Commun. 1998; 246:293-298.
- Rivas CI, Vera JC, Guaiquil VH, et al. Increased uptake and accumulation of Vitamin C in human immunodeficiency virus 1-infected hematopoietic cell lines. J Biol Chem. 1997; 272:5814-5820.
- Ross AC, Stephensen CB. Vitamin A and retinoids in antiviral responses. FASEB J. 1996; 10:979-985.
- Ross AC. Vitamin A and retinoids. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:305-327.
- Rowe DJ, Ko S, Tom XM, et al. Enhanced production of mineralized nodules and collagenous proteins in vitro by calcium ascorbate supplemented with vitamin C metabolites. J Periodontol. 1999; 70:992-929.
- Sakagami H, Satoh K, Hakeda Y, Kumegawa M. Apoptosis-inducing activity of vitamin C and vitamin K. Cell Mol Biol. 2000; 46:129-143.
- Satterlee DG, Aguilera-Quintana I, Munn BJ, Krautmann BA. Vitamin C amelioration of the adrenal stress response in broiler chickens being prepared for slaughter. Comp Biochem Physiol A 1989;94:569-74.
- Schwartz J, Weiss ST. Dietary factors and their relation to respiratory symptoms. The Second National Health and Nutrition Examination Survey. Am J Epidemiol. 1990;132:67-76. West KP Jr, Pokhrel RP, Katz J, et al. Efficacy of vitamin A in reducing preschool child mortality in Nepal. Lancet. 1991; 338:67-71.
- Semba RD. The role of vitamin A and related retinoids in immune function. Nutr Rev. 1998 Jan;56(1 Pt 2):S38-48.
- Semba RD. Vitamin A and immunity to viral, bacterial and protozoan infections. Proc Nutr Soc. 1999 Aug;58(3):719-27.
- Semba RD. Vitamin A, immunity, and infection. Clin Infect Dis. 1994 Sep;19(3):489-99.
- Simon JA, Hudes ES. Relationship of ascorbic acid to blood lead levels. J Amer Med Assoc. 1999; 281:2298-2293.
- Simon JA, Hudes ES. Serum ascorbic acid and gallbladder disease prevalence among US adults. The Third National Health and Nutrition Examination Survey (NHANES III). Arch Intern Med. 2000; 160:931-936.
- Skaper SD, Fabris M, Ferrari V, et al. quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Rad Biol Med. 1997; 22:669-678.
- Sohlenius-Sternbeck A-K, Appelkvist E-L, De Pierre JW. Effects of vitamin A deficiency on selected xenobiotic-metabolizing enzymes and defenses against oxidative stress in mouse liver. Biochem Pharmacol. 2000; 59:377-383.
- Sugimoto K, Tobian L, Ishimutsu T, Lange JM. High potassium diets greatly increase growth-inhibiting agents in aortas of hypertensive rats. Hypertension. 1992; 19:749-752.
- Sugimoto T, Tobian L, Ganguli MC. High potassium diets protect against dysfunction of endothelial cells in stroke-prone spontaneously hypertensive rats. Hypertension. 1988:11:579-585.
- Taddei S, Virdis A, Ghiadoni L, et al. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation. 1998; 97:2222-2229.
- Tannen RL. Effects of potassium on blood pressure control. Ann Intern Med. 1983; 98(part 2):773-780.
- Thurnham DI. Micronutrients and immune function: some recent developments. J Clin Pathol. 1997 Nov;50(11):887-91.
- Tobian L. Salt and hypertension. Lessons from animal models that relate to human hypertension. Hypertension. 1991; 17:152-158.
- Tsukaguchi H, Tokui T, Mackenzie B, et al. A family of mammalian Na-dependent L-ascorbic acid transporters. Nature. 1999; 399:70-75.
- Underwood BA, Arthur P. The contribution of vitamin A to public health. FASEB J. 1996; 10:1040-1048
- Valkonen MM, Kuusi T. Vitamin C prevents the acute atherogenic effects of passive smoking. Free Rad Biol Med. 2000; 28:428-436.
- Van Hooser JP, Aleman TS, He Y-G, et al. Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness. Proc Natl Acad Sci USA. 2000; 97:8623-8628.
- Verlangieri AJ, Fay MJ, Bannon AW. Comparison of L-ascorbic acid and Ester C in the non-ascorbate synthesizing Osteogenic Disorder Shionogi (ODS) rat. Life Sci. 1991; 48:2275-2281.
- WangY, Mackenzie B, Tsukaguchi H, et al. Human vitamin C (L-ascorbic acid) transporter SVCT1. Biochem Biophys Res Commun. 2000; 267:488-494.
- West SG, Light KC, Hinderliter AL, et al. Potassium supplementation induces beneficial cardiovascular changes during rest and stress in salt sensitive individuals. Health Psychol. 1999; 18:229-240.
- Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical triglyceride trials. JAMA. 1997; 277:1624-1632.
- Young DB, Lin H, McCabe RD. Potassium's cardiovascular protective mechanisms. Am J Physiol. 1995; 268:R825-R837.
- Young DB, Ma G. Vascular protective effects of potassium. Semin Nephrol. 1999; 19:477-486
- Zhang HM, Wakisaka N, Maeda O, Yamamoto T. Vitamin C inhibits the growth of a bacterial risk factor for gastric carcinoma: Helicobacter pylori. Cancer. 1997; 80:1897-1903.
- Zhou MS, Nishida Y, Yoneyama H, et al. Potassium supplementation increases sodium excretion in hypertensive Dahl rats. Clin Exp Hypertens. Agus DB, Gambhir SS, Pardridge WM, et al. Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. J Clin Invest. 1997; 100:2842-2848.
- Zhou X, Xie M, Niu C, Sun R. The effects of dietary vitamin C on growth, liver vitamin C and serum cortisol in stressed and unstressed juvenile soft-shelled turtles (Pelodiscus sinensis). Comp Biochem Physiol A Mol Integr Physiol 2003;135:263-70.
- Zollinger PE, Tuinebreijer WE, Kreis RW, Breederveld RS. Effect of vitamin C on frequency of reflex sympathetic dystrophy in wrist fractures: a randomized trial. Lancet. 1999; 354:2025-2028.
What is the recommend daily allowance of Vitamin C?
The RDA for the average adult male is 90 mg a day and, for adult females, it is 75 mg a day.
Does Isotonix Vitamin C provide the recommended daily allowance?
Yes, Isotonix Vitamin C contains 500mg of vitamin C per serving, which is an optimal amount for immune system support.
Can Isotonix Vitamin C support my immune system?
Yes, in several ways actually. Vitamin C has been heralded for quite possibly being the best immune system supporter and antioxidant available today. Vitamin C supports the immune system by protecting the body from free radical damage. As a water-soluble vitamin, ascorbic acid performs its antioxidant functions within the aqueous compartments of the blood and inside cells and can help restore the antioxidant potential of vitamin E (a fat-soluble antioxidant). Support of immune cell function is also a key role performed by vitamin C.*
Who needs to supplement with Isotonix Vitamin C?
Basically, everyone over 18 should use Isotonix Vitamin C Formula to add vitamin C to their diet, because very few of us, get the recommended five servings of fruits and vegetables in our daily diets. Those who may especially need supplemental vitamin C include the elderly, those with weakened immune systems, smokers, those under heavy amounts of stress and athletes.*
Is it possible to take too much Isotonix Vitamin C?
Ascorbic acid is extremely safe even at relatively high levels (because most of the excess is excreted in the urine). At high doses (over 1000 mg/day), some people can experience gastrointestinal side effects such as stomach cramps, nausea and diarrhea.
How does Isotonix Vitamin C support cardiovascular health?
It helps maintain healthy cholesterol and triglyceride levels. It promotes strong arterial walls and supports normal blood pressure. It helps the body maintain vitamin E, which has known benefits for the cardiovascular system. Vitamin C supports normal platelet activity.*