The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.
Protein Interaction Networks : Computational Analysis General
| ISBN | 9780521888950 |
| Fiction/Non-Fiction | Non-Fiction |
| Publisher | Cambridge Univ Pr |
| Pages | 278 |
| List Price | $84.00 |
| Author | Zhang, Aidong |
| Publication Date | 04/06/2009 |
| Release Status | In Print |
| Format | Hardcover |
| Language | English |
| Measurements | Height: 10 Inches (US)Width: 7 Inches (US)Thickness: 0.75 Inches (US)Unit Weight: 1.55 Pounds (US) |
| Edition Number | 1 |
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