Protein-Protein Interactions as New Drug Targets

Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions.This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.

General

ISBN		9783642091940
Fiction/Non-Fiction		Non-Fiction
Publisher		Springer Verlag
Pages		527
List Price		$479.00
Publication Date		11/19/2010
Release Status		In Print
Format		Paperback
Language		English
Series		Handbook of Experimental Pharmacology
Editor		Klussmann, Enno Scott, John