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Vitamin D and Cancer (Hardcover)

Vitamin D and Cancer (Hardcover)

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Item  9781441971876

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Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to ...
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Vitamin D and Cancer (Hardcover)
Vitamin D and Cancer
Item 9781441971876
Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.
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Vitamin D and Cancer (Hardcover)
Vitamin D and Cancer
Item 9781441971876
Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.
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Vitamin D and Cancer (Hardcover)
Vitamin D and Cancer by Trump, Donald L./ Johnson, Candace S. [Hardcover]
Item UBM9781441971876
This volume summarizes the considerable data supporting the role of vitamin D in cancer therapeutics and prevention. It outlines the importance of vitamin D for cancer researchers and clinicians. *Author: Trump, Donald L./ Johnson, Candace S. *Binding Type: Hardcover *Number of Pages: 342 *Publication Date: 2010/12/15 *Language: English *Dimensions: 9.20 x 6.20 x 0.90 inches
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Product Info

Substantial data indicate the broad importance of vitamin D-based signaling in normal human physiology and the broad effects of vitamin D deficiency. Vitamin D may play a role not only in the control of bone and mineral metabolism, but also appears to be involved in immune function, cardiovascular health, thrombosis and vasculogenesis and neuromuscular function. Considerable epidemiologic data demonstrate that low vitamin D serum levels occur very commonly in normal adult populations and that vitamin D deficiency is associated with an enhanced risk of cancer death from lung, prostate, head & neck, colorectal and other gastrointestinal cancers. In addition, preclinical data provide evidence that calcitriol and other active analogues of calcitriol have anti-proliferative, pro-differentiative, pro-apoptotic and anti-angiogenic activity in numerous in-vitro and in-vivo models. It is quite clear that, while it requires high exposure to calcitriol to induce these effects, such exposure can be readily achieved when high dose intermittent therapy is given.


Vitamin D and Cancer (Hardcover)
General
ISBN

9781441971876

Fiction/Non-Fiction

Non-Fiction

Publisher

Springer Verlag

Pages

342

List Price

$219.00

Publication Date

10/01/2010

Release Status

In Print

Format

Hardcover

Language

English

Measurements

Height: 9.25 Inches (US)

Width: 6.25 Inches (US)

Thickness: 0.75 Inches (US)

Unit Weight: 1.4 Pounds (US)

Editor

Johnson, Candace S.

Trump, Donald L.

 
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