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Dealing with the symptoms of menopause and premenstrual syndrome is difficult for many women. Many mild symptoms of menopause and premenstrual syndrome can be addressed through the use of supplementation.*
Prime Feminene Female Support Formula is a dietary supplement to help women reduce the discomfort of mild symptoms associated with both menopause and premenstrual syndrome. Prime Feminene utilizes three unique ingredients – Lifenol®, maca and chaste berry extract – scientifically formulated to help women maintain a healthy, normal hormonal balance which helps stabilize mood, helps reduce menopausal symptoms like hot flashes and night sweats, and helps counteract the mild effects of PMS.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
- Helps to reduce hot flashes and night sweats associated with menopause
- Helps stabilize mood
- May help maintain normal hormone balance
- Helps alleviate mild symptoms commonly associated with menopause
- Helps counteract mild effects of PMS
- Helps maintain optimal female health
Lifenol® Hop Extract ( Humulus lupulus ) 85 mg
Lifenol hop extract is a patented extract of hops. This specific extract is unique because it contains prenylflavonoids, including 8-prenylnaringenin (8-PN), a very active phytoestrogen. Published studies have revealed a strong link between the estrogenic activity of hops and their 8-PN activity.
Lifenol’s unique profile has been shown to have positive effects on mild menopausal concerns, especially hot flashes and night sweats. Clinical studies show significant reductions in the number of hot flashes, as well as an improved quality of life in menopausal women. Women supplemented with hops extract showed decreases in total menopausal discomforts, including a decrease in the number of hot flashes and night sweats.
Researchers believe that it is through 8-PN’s activity of binding to alpha- and beta-estrogen receptors that hops extract exerts much of its action in regards to menopausal issues.*
Maca Root ( Lepidium meyenii ) 250 mg
Maca is a Peruvian plant resembling a radish and has an odor similar to butterscotch. It has been cultivated as a vegetable crop in the Andes mountains for at least 3,000 years. The applicable part of maca is the root and its constituents include sterols, minerals, lipids and others.
Researchers believe maca works as an adaptogenic herb and helps modulate the body’s response to stress. Clinical trials specifically demonstrate effects for maintaining energy, decreasing stress and relieving discomfort associated with menopause.
Maca also helps provide support for menopause by helping stabilize mood. As a member of the broccoli family, maca also contains glucosinolates, which may work to support cellular health.*
Chaste Berry Extract ( Vitex agnus-castus ) 200 mg
Chaste berry extract, or Vitex, is a shrub native to the Mediterranean and Central Asia, but can also be found around the United States. It is generally used in dietary supplements for helping to maintain normal levels of female hormones and for mild menopausal concerns. It has several active constituents, including diterpenes, flavonoids, essential oils and glycosides.*
What is menopause, and when does it start?
Menopause is the ceasing of the monthly female menstrual cycle. Some common symptoms of menopause include hot flashes, night sweats, mood swings and sleeplessness.
The average age of menopause in the United States is 52 years old; yet the age of onset varies and can occur anytime between 40 and 60. Prior to menopause, some women experience perimenopause, a time period that can include many of the symptoms of menopause before menstruation stops.
What is PMS, and what are its symptoms?
Premenstrual syndrome, or PMS, occurs for up to two weeks prior to menstruation. PMS has been associated with a deficiency or excess of hormones, nutritional deficiencies and stress, as well as other nutritional and lifestyle factors.
Symptoms of PMS include increased levels of anger and stress, bloating, breast tenderness and sensitivity, abdominal discomfort, sadness, short-term fatigue, head discomfort, hostility, trouble sleeping, joint discomfort, mood swings, nervousness and tension.
How can Prime Feminene help maintain hormonal balance?
The unique ingredients included in Prime Feminene have been shown in studies to help modulate the body’s response to a number of hormonal triggers, both internally and externally.
One of these factors is estrogenic activity, or EA, which is considered a hormone disruptor. Estrogen, the primary female sex hormone, plays a significant role in women’s mental health, and maintaining normal levels of estrogen are necessary to reduce the symptoms of perimenopause and postmenopause.
According to studies, certain synthetic and naturally occurring chemicals – also called hormone disruptors – can interfere with these processes and lead to adverse effects. The ingredient Lifenol® is rich in prenylflavonoids – specifically 8-prenylnaringenin (8-PN), a very active phytoestrogen – and has been shown to have positive effects on menopausal concerns related to estrogenic activity, including hot flashes and night sweats.
Clinical trials and studies have found that maca, an adaptogenic herb, helps control the body’s response to stress, while also helping to maintain energy and relieve mild discomfort associated with menopause. Maca has also been shown to help stabilize mood.
Chaste berry extract is traditionally used to promote normal levels of female hormones and for mild menopausal concerns. Its ability to support normal hormone balance and promote a healthy menstrual cycle is due in large part to its phytochemical makeup, which includes diterpenes, flavonoids, essential oils and glycosides.*
What is the recommended serving for Prime Feminene?
As a dietary supplement, women should take one (1) capsule daily, or as directed by your healthcare provider.
Are there any warnings associated with taking Prime Feminene?
If you are currently taking any prescription medication or have an ongoing medical condition, or if you are pregnant or breastfeeding, you should consult with your healthcare provider before using this product. If you are allergic to any of the ingredients listed, you should not take this product.
What is Lifenol®?
Lifenol is patented extract from hops cones that has been shown in numerous clinical studies to significantly reduce the instances of hot flashes and improve the quality of life in menopausal women. In studies, women who supplemented with hops extract showed decreases in total menopausal discomforts, including a decrease in the number of hot flashes and night sweats.*
- van Die MD, Burger HG, Teede HJ, Bone KM. Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials. Planta Med. 79(7):562-75, 2013.
- Schellenberg R, Zimmermann C, Drewe J, Hoexter G, Zahner C. Dose-dependent efficacy of the Vitex agnus castus extract Ze 440 in patients suffering from premenstrual syndrome. Phytomedicine. 19(14):1325-31, 2012.
- Bowe, J., et al. The hop phytoestrogen, 8-prenylnaringenin, and reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes. Journal of Endocrinology. 191: 399-405, 2006.
- Carmichael, A. Can Vitex agnus castus be used for the treatment of mastalgia? What is the current evidence? eCAM. 5(3): 247-250, 2008.
- Chadwick, L., et al. The pharmacognosy of Humulus lupulus L. (hops) with an emphasis on estrogenic properties. Phytomedicine. 13(1-2): 119-131, 2006.
- Erkkola, R., et al. A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts. Phytomedicine: International Journal of Phytotherapy & Phytopharmacology. 17(8): 389-396, 2010.
- Gardiner, P. Chasteberry (Vitex agnus castus). Longwood Herbal Task Force. , 2000. Last viewed online 9/29/2010.
- Heyerick, A., et al. A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts. Maturitas. 54(2): 164-175, 2006.
- Leonhardt, J., et al. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Experimental and Clinical Endocrinology. 102(6): 448-454, 1994.
- Liu, J., et al. Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus castus L. (chaste-berry). Phytomedicine. 11: 18-23, 2004.
- Loch E., et al. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. Journal of Women’s Health and Gender-Based Medicine. 9(3): 315-320, 2000.
- Milligan, S., et al. Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. Journal of Clinical Endocrinology & Metabolism. 83(6): 2249-2252, 1999.
- Monograph. Humulus lupus. Alternative Medicine Review. 8(2): 190-192, 2003.
- Wuttke, W., et al. Chaste tree (Vitex agnus castus)- pharmacology and clinical indications. Phytomedicine. 10: 348-357, 2003.
- Carroll, D. Nonhormonal therapies for hot flashes in menopause. American Family Physician. 73(3): 457-465, 2006.
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- Berger, D., et al. Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome (PMS). Archives of Gynecology and Obstetrics. 264(3): 150-153, 2000.
- Israel, D. and Youngkin, E. Herbal therapies for perimenopausal and menopausal complaints. Pharmacotherapy. 17(5): 970-984, 1997.
- Shaw, C. The perimenopausal hot flash: epidemiology, physiology, and treatment. Nurse Practitioner. 22(3): 55-56, 61-66, 1997.
- Sliutz, G., et al. Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Hormone and Metabolic Research. 25(5): 253-255, 1993.
- Meissner HO et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (II) Physiological and Symptomatic Responses of Early-Postmenopausal Women to Standardized doses of Maca in Double Blind, Randomized, Placebo-Controlled, Multi-Centre Clinical Study. Int J Biomed Sci.2(4):360-74, 2006.
- Meissner HO, et al. Hormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (III) Clinical responses of early-postmenopausal women to Maca in double blind, randomized, Placebo-controlled, crossover configuration, outpatient study. Int J Biomed Sci. 2(4):375-94, 2006.
- Meissner HO, Kapczynski W, Mscisz A, Lutomski J. Use of gelatinized maca (lepidium peruvianum) in early postmenopausal women. Int J Biomed Sci. 1(1):33-45, 2005.
- Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo-controlled study. BMJ. 322:134-7, 2001.
- Bolca S et al. Disposition of hop prenylflavonoids in human breast tissue. Mol Nutr Food Res. 54 Suppl 2:S284-94, 2010.
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It's so good
Feminene - Bring back old formula
the old formula worked miracles. PMS symptoms lessened, night sweats and sleepless night - gone. This new formula is not effective at all. PMS is a nightmare, along with the return of the night sweats - covers on, covers off - all night, leading to sleepless nights AGAIN. PLEASE, PLEASE, PLEASE bring back the old formula. I always recommended the old formula, but not the new one.
Why Fix what wasn't broken
Why? I just want to know why you changed the formulation.I'm suffering now. And I'm not going to spend money for 6 - 8 months hoping this new product will work.Especially when the original was excellent.
Why the change?
I have used Feminene for 4 years, it was a life changing for me for I would only have one good week a month. After starting this product my husband would even give a testimonial how much easier it was to live with me :) Then there was the switch the new Feminene, I stocked up on the old for I feared the worse of going back to the old me. Once I changed over it was the worse month I had for 4 ye
not like the original formula
this new formula is not effective & more expensive. the original formula stopped night sweats decreased the severity of hot flashes & stablized mood. please bring back the original formula. menapausal women need the relief & comfort from the original formula.