Transform food into energy!
100 mg
The multi-enzyme complex, DigeZyme® helps digest starch, cellulose fibers, fats, proteins and lactose sugar in dairy products.
150M CFU
of Lactospore® (bacillus coagulans) supports healthy balance of good bacteria in the gut.

Digestive Enzymes Found In DigeZyme®‡
DigeZyme® [Amylase, Protease, Cellulase, Lactase, Lipase] is a multienzyme that collectively supports the breakdown of complex macromolecules into energy sources and promotes the release of the nutrient content from the foods we eat.

Product Classification

Isotonic

Vegan

Dairy Free

Gluten-Free

Non-GMO

Good Manufacturing Practices
Directions For Use

Pour one small capful (3.3g) of Isotonix Digestive Enzymes with Probiotics into a cup.

Mix in 2 oz of water for each capful.

Take with or immediately following a meal for maximum benefits.
Key Ingredients & Benefits

Magnesium (Carbonate)*
Promotes normal synthesis of proteins
Supports cardiovascular health

Potassium (Bicarbonate)*
Helps maintain fluid balance
Contributes to a sense of well-being

Bacillus Coagulans (Lactospore®§)*
Produces good bacteria
Promotes digestive and gastrointestinal health

DigeZyme®‡ [Amylase, Protease, Cellulase, Lactase, Lipase]*
Promotes digestion and absorption of nutrients
Provides enzymes and good bacteria that promote the digestion and absorption of nutrients
Supports a healthy digestive tract
On-the-Go Digestive Support
Promote the absorption of nutrients. This digestive health promoting supplement features a formula of digestive enzymes and probiotics, including DigeZyme® — a blend of amylase, protease, cellulase, lactaase and lipase — and Lactospore® (bacillus coagulans) probiotic.
Isotonix Delivery System

:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.

:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What happens when we eat?
Digestion begins before we even eat — smelling food triggers saliva production. In the stomach, acid and enzymes break down food, which is further processed in the small intestine for nutrient absorption. The process continues in the large intestine, where nutrients are extracted.
What are digestive enzymes?
Digestive enzymes help break down food, improving the absorption of nutrients like proteins, starch, fats and sugars. They work in the gastrointestinal tract to support more efficient digestion.
What are the different types of digestive enzymes?
Protease breaks down proteins, amylase digests starch and lipase digests fats. Specialty enzymes like lactase, maltase, sucrase and cellulase help digest specific sugars and fibers, aiding in nutrient release.
What are probiotics?
Probiotics are beneficial bacteria that support digestive and immune health; they help maintain a healthy balance of gut bacteria. Isotonix Digestive Enzymes with Probiotics contains bacillus coagulans, a probiotic that produces lactic acid but isn’t classified as a lactic acid bacteria.
Research Scope
Reference List
- Anonymous. Lactobacillus Sporogenes. Alternative Medical Review. 7(4): 340-342, 2002.
- Bourlioux, P., et al. The Intestine and Its Microflora are Partners for the Protection of the host: Report on the Danone Symposium “The Intelligent Intestine,” Held in Paris, June 14, 2002. American Journal of Clinical Nutrition. 78: 675-683, 2003.
- Casula, G. and Cutting, S. Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract. Applied and Environmental Microbiology. 68(5): 2344-2352, 2002.
- De Vecchi, E. and Drago, L. Lactobacillus Sporogenes or Bacillus Coagulans: Misidentification or Mislabeling? International Journal of Probiotics and Prebiotics. 1(1): 3-10, 2006.
- Feinle-Bisset, C., et al. Fat Digestion is Required for Suppression of Ghrelin and Stimulation of Peptide YY and Pancreatic Polypeptide Secretion by Intraduodenal Lipid. American Journal of Physiology: Endocrinology and Metabolism. 289: E948-E953, 2005.
- Lee, M., et al. Total Intestinal Lactase and Sucrase Activities Are Reduced in Aged Rats. Journal of Nutrition. 127(7): 1382-1387, 1997.
- Meisel, J. Commensal microbiota modulate gene expression in the skin. Microbiome. 6(1): 20, 2018
- Nichols, B., et al. The Maltase-Glucoamylase Gene: Common Ancestry to Sucrase-Isomaltase with Complementary Starch Digestion Activities. Proceedings of the National Academy of Sciences of the United States of America. 100(3): 1432-1437, 2003.
- O’Dea, K., et al. Rate of Starch Hydrolysis in Vitro as a Predictor of Metabolic Responses to Complex Carbohydrate In Vivo. American Journal of Clinical Nutrition. 34: 1991-1993, 1981.
- Sanders, M., et al. Sporeformers as Human Probiotics: Bacillus, Sporolactobacillus, and Brevibacillus. Comprehensive Reviews in Food Science and Food Safety. 2: 101- 110, 2003.
- Vaughn, A. R., et al. Skin-gut axis: The relationship between intestinal bacteria and skin health. World Journal of Dermatology. 6(4): 52-58, 2017
Product Label Details
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
‡DigeZyme® is a registered trademark of the Sabinsa Corporation.
∅DU, PC, CU, LAC, FIP, and SU are units of enzyme activity.
§Lactospore® is a registered trademark of the Sabinsa Corporation.
¶CFU = colony-forming units.

Reviews
Customer Rating
4.8 out of 5 star rating.
(194 reviews)
would recommend this product.
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Customer Images
This tastes so yummy and works so well.
Response from Customer Service on 03/24/2025
Thank you for your delightful review of Isotonix® Digestive Enzymes with Probiotics! We're thrilled to hear that you find it both delicious and effective. Your satisfaction with the taste and results truly means a lot to us. If you have any questions or need assistance, please don't hesitate to reach out. Thank you for choosing our product and sharing your positive experience!
Clean feeling
by SusanK
on 02/17/2025
I tried this product before I tried it I had doubts that it may be like all the others saying it can help with your digestive system and they don’t but this product right here it handle it business and stand on its own would recommend to all
Response from Customer Service on 02/18/2025
Thank you for sharing your experience with the Isotonix® Digestive Enzymes with Probiotics (Packets)! We're delighted to hear that it exceeded your expectations and provided the clean feeling you were looking for. It's wonderful to know that you would recommend it to others. Your feedback is incredibly valuable to us, and we appreciate your trust in our product!
Love them!
by rosannc
Shop Consultant
on 02/10/2025
These digestive enzymes are my "Go to" products to help me when I have a full meal. But I also take them at night before bed along with my isotonix magnesium and fiber powder.
Response from Customer Service on 02/11/2025
Thank you for your wonderful review of Isotonix® Digestive Enzymes with Probiotics (Packets)! We’re delighted to hear that they have become your "go-to" product for support after a full meal and as part of your nightly routine with magnesium and fiber powder. Your trust and satisfaction with our products mean a lot to us, and we’re thrilled to be a part of your daily regimen. Thank you for choosing Isotonix® and for sharing your positive experience!
No more TUMS!!!
by ErikaW
Shop Consultant
on 01/31/2025
I did not realize how much I needed this in my life! I reached out to my health and wellness coach about my 8 year old dealing with tummy issues. She immediately suggested Digestive Enzymes! I ordered that day and received it the next. I was worried that my picky kiddo would not drink it but he did! And he loves it! He calls it his special drink. My husband used to eat tums like candy. Now, he takes Digestive Enzymes and hasn't looked back! It has been a huge help to my entire family!
Response from Customer Service on 02/03/2025
Thank you for sharing your heartwarming experience with Isotonix® Digestive Enzymes with Probiotics! We're thrilled to hear that it has become a valuable addition to your family's daily routine and that your son enjoys his "special drink."
It's wonderful to know that the product has been a great help for both him and your husband. Your feedback is truly appreciated, and we're delighted that your health and wellness coach recommended us. Thank you for trusting Isotonix® for your family's wellness
Incredible
by ChristinaM
on 01/30/2025
I notice it worked right away. 💯 will buy again.
Response from Customer Service on 01/30/2025
Thank you for your fantastic review of nutraMetrix Isotonix® Digestive Enzymes with Probiotics! We're thrilled to hear that you have experienced such positive and immediate benefits and are delighted with the changes you've noticed. Your feedback is invaluable to us, and your enthusiasm for purchasing again truly means a lot. We appreciate your trust in our product, and we're honored to support you on your wellness journey.
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