Love is in the Air
5 out of 5 star rating. 
Triple Threat Daily Regimen
Isotonix OPC-3
95% intestinal nutrient delivery for max absorption
Isotonix Magnesium
Support 300+ enzyme systems
Prime NAD+
The secret to healthy aging
Includes our top seller, Isotonix OPC-3
The super antioxidant in OPC-3, pine bark extract (Pycnogenol®)
Isotonix OPC-3 contains the only isotonic form of Pycnogenol®, is a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and powerful bioflavonoids in the world.
Product Classification
Vegan
Gluten-Free
No Detectable GMO
Good Manufacturing Practices
Directions for Use
Step 1 (Morning): Take Isotonix OPC-3 and the first capful of Isotonix Magnesium when you wake up.
Step 2 (Midday): Take Prime NAD+ before your midday meal.
Step 3 (Evening): Take the second capful of Isotonix Magnesium before you go to bed.
Key Ingredients & Benefits
Isotonix OPC-3®: Pycnogenol®‡, Pine Bark Extract*
Supports the normal dialation of blood vessels
Provides complete antioxidant protection
Combats free radicals
Supports a healthy complexion
Promotes healthy sperm quality
Isotonix OPC-3®: Bilberry Extract*
Powerful antioxidant
Supports healthy vision
Maintains healthy circulation
Isotonix® Magnesium: Magnesium (Citrate & Glycinate)*
Helps the body maintain a healthy level of magnesium, combatting magnesium deficiency
Promotes muscle health and comfort
Supports a healthy sleep quality
Promotes bone health
Prime Anti-Aging Nutraceuticals® NAD+: Nicotinamide Riboside (crystalline nicotinamide riboside chloride)*
Supports healthy NAD production
Combat the cellular aging process
Promotes normal activity of the SIRT-1 gene
Supports cellular health and metabolism
Revitalize Your Body With Core 3 Health
Restore, rebuild and reset with Core 3 Health: three powerful products in three simple steps. Our hottest health superstars have been carefully selected for one triple-threat system for maximum effect and truly amazing results.
Frequently Asked Questions
When is the best time to take these products?
Take Isotonix OPC-3 and Isotonix Magnesium in the morning. Take Prime NAD+ 4–5 hours later, then another serving of Isotonix Magnesium before bed. This 1-2-3 system supports metabolic health and sleep.
Why is there sugar in Isotonix products?
The sugars make the solution isotonic, enhancing nutrient absorption into the bloodstream and optimizing the delivery of nutrients to target cells.
Does Core 3 Health work for second or third shift workers?
Yes, follow the 1-2-3 schedule based on your sleep cycle. Take Isotonix OPC-3 and Magnesium when you wake up, Prime NAD+ 4-5 hours later and Magnesium before bed.
What makes Isotonix OPC-3 unique?
Isotonix OPC-3 is delivered in an isotonic form for quick absorption. It combines powerful antioxidants like Pycnogenol®, bilberry, and grape seed extracts, supporting cardiovascular health, joint flexibility, and free radical protection.
What makes Isotonix Magnesium unique?
Isotonix Magnesium provides 400 mg of highly bioavailable magnesium forms (glycinate and citrate), supporting brain function, muscle health, and stress management.
What makes Prime NAD+ unique?
Prime NAD+ supports NAD+ levels with 250 mg of nicotinamide riboside (NR) and 50 mg of pterostilbene, supporting cellular regeneration, mitochondrial health, and DNA integrity.
Research Scope on Core 3 Health
100
The number of active compounds found in Red Wine Extract
30+
trillion cells in the body are fueled by the NAD molecule
300
Magnesium supports more than 300 enzyme systems
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
‡As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.
Reviews
Break down of ratings: (57) 5 star ratings. (3) 4 star ratings. (0) 3 star ratings. (0) 2 star ratings. (0) 1 star ratings.
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Marlene J. Rydingsword
My Product Review
5 out of 5 star rating.
So happy I started taking Core 3 Health. It is a great combination of nutrients that has made a difference in my energy levels, ability to sleep and feeling less pain in my joints. Love the ease of taking it and the fact there are no downsides to the products. Thanks so much Shop.com!!
Must TRY
4 out of 5 star rating.
All three products are extremely beneficial independent of each other. I enjoy the feeling of energy in the morning after I start my day. NAD+ before meal time promotes a better quality of life in addition to cutting graving. I started taking this product when it first was release and will continue.
Response from Customer Service on 03/24/2025
Thank you for your insightful review of Core 3 Health! We’re delighted to hear that you find each of the three products beneficial on their own and that they contribute to your morning energy and overall quality of life. It's wonderful to know that you've been with us since the product's release and plan to continue. Your satisfaction and continued support mean a lot to us. If you have any questions or need assistance, please don’t hesitate to reach out. Thank you for choosing our product and sharing your positive experience!
changed the game
5 out of 5 star rating.
I feel so good!
Response from Customer Service on 02/25/2025
Thank you for your uplifting review of Core 3 Health! We're thrilled to hear that it's made you feel so good and has truly changed the game for you. Your satisfaction and well-being are our top priorities, and we're delighted to be a part of your positive experience. Thank you for choosing Core 3 Health!
CORE 3 LIFE!
5 out of 5 star rating.
Core3 Health regimen has been instrumental in my overall cognitive health, maintaining energy levels throughout my busy schedule & turning back the hands of time as I get close to 60 yrs young!
Response from Customer Service on 02/11/2025
Thank you for your amazing review of Core 3 Health! We’re thrilled to hear that our regimen has been instrumental in supporting your cognitive health, maintaining your energy levels, and helping you feel youthful. Your journey and feedback truly inspire us, and we’re honored to be a part of your daily routine. Thank you for choosing Core 3 Health and for sharing your positive experience with us!
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