Fortify Your Calcium Intake
5 Salts
Unlike most calcium products that rely on just one or two basic forms, this advanced blend features five distinct calcium salts, each selected for their superior bioavailability and complementary health benefits.
375 mg
of calcium in one serving of Isotonix® Calcium Plus. While leafy greens are healthy, supplements can ensure consistent and bioavailable calcium intake—especially for those with increased needs.

Charge Up with Calcium
Calcium is a cornerstone of everyday health, and Isotonix® Calcium Plus is designed to deliver it better. Our advanced formula blends multiple bioavailable calcium salts in an isotonic form—helping it remain in a charged, ready-to-absorb state as it moves through your body. The result? Faster uptake, better utilization, and stronger support for the life you live today and tomorrow. It's calcium, elevated.

Isotonix® Calcium Plus
Full-Spectrum Support for a Stronger You
Calcium isn't just about strong bones—it's a critical mineral your body needs for dozens of daily functions. That’s why Isotonix Calcium Plus is designed to go beyond the basics. Each form of calcium in our formula is carefully chosen to meet the body’s different absorption needs and physiological demands—helping ensure more complete, targeted support where it matters most.*

Product Classification

Good Manufacturing Practices

Isotonic

Gluten-Free

No Detectable GMO

Vegetarian

Dairy Free
Directions For Use

Pour 1 small capful (3.3 g) of Isotonix Calcium Plus into your favorite cup.

Add 2 fl oz of water for each capful and stir.

For best results take twice daily - 1 capful in the morning and evening. If mixed with other Isotonix products, add 2 oz of water for each capful.
Key Ingredients & Benefits

Vitamin D3 (Cholecalciferol)*
Adequate calcium and vitamin D as part of a healthful diet, along with physical activity, may reduce the risk of osteoporosis in later life
Promotes the absorption of calcium and phosphorus
Supports the production of several proteins involved in calcium absorption and storage

Magnesium (Oxide, Carbonate)*
Promotes normal functioning of muscle and nervous tissue
Promotes the normal synthesis of all proteins, nucleic acids, lipids and carbohydrates
Helps combat oxidative stress and lipid peroxidation

Calcium (Carbonate, Lactate, Phosphate, Sulfate, Citrate)*
Supports cardiovascular health
Supports normal muscle contraction and nerve health
Supports healthy energy production
Helps to ease the discomfort of PMS

Manganese (Sulfate)*
Supports healthy blood sugar levels
Promotes normal blood clotting
Supports the normal formation of connective tissue, bones and sex hormones
Promotes normal brain and nerve function

Riboflavin (5-Phosphate)*
Promotes healthy red cell formation and nervous system function
Provides antioxidant support
Promotes energy production

Potassium (Bicarbonate, Citrate)*
Supports proper nerve conduction
Plays a critical role in the normal contraction of cardiac, skeletal and smooth muscles
Maintain Your Frame
Your body needs more than just calcium, it needs the right form, in the right balance, for strong bones, heart health and overall wellness. Packed with an unbeatable blend of essential calcium salts, vitamin C, D and magnesium, this cutting-edge isotonic solution is your ultimate ally for maintaining skeletal health and is key for supporting heart rhythm and normal muscle function. Isotonix® Calcium Plus is ionized upon mixing, making it ready for your body to absorb and use immediately—without waste.
Isotonix Delivery System

:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.

:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
If I am not an elderly woman, why should I take a calcium supplement?
Calcium plays a huge role in regulating many major bodily processes with implications that extend far beyond the age factor. Other than elderly women who may be susceptible to bone loss, younger women, pregnant and lactating women, and men should take a calcium supplement. Younger women need more calcium to build up the strength of their bones. Pregnant and lactating women need extra calcium needs to foster the healthy growth of new cells and of breast milk.
I have heard calcium is great for PMS? How so?
PMS is an undesirable influence on physical and psychological peace of mind. Recent studies have found that over 70 percent of relationships are affected in some way by PMS. So PMS impacts nearly everyone, including men! Supplementation with calcium can reduce PMS symptoms. In a study conducted by the US Department of Agriculture's Human Nutrition Research Center, it was found that women on a high calcium diet had decreased irritability, cramping and bloating associated with PMS. Ovarian hormones affect calcium, magnesium and vitamin D metabolism. Estrogen regulates calcium metabolism, intestinal calcium absorption and parathyroid gene expression and secretion, triggering fluctuations across the menstrual cycle. As a woman menstruates, her hormones are "all over the place." Clinical trials in women with PMS have found that calcium supplementation helps reduce mood and somatic symptoms associated with PMS.
If we only absorb 300 to 400 mg of calcium at a time, why does one serving contain 750 mg?
There are 750 mg of calcium in 2 capfuls of Isotonix Calcium Plus. Therefore, one capful equals 375 mg of calcium. For this reason, it is recommended to only take one capful at a time: one in the morning and one in the evening.
Why is Isotonix Calcium Plus better than other calcium products?
It is better because of the Isotonix delivery system. The secret of the isotonic process is probably now becoming clear! When an isotonic substance enters the body, it will be absorbed into the bloodstream rapidly. With isotonic fluids, little nutritive value is lost making the absorption of nutrients highly efficient. There is nothing artificial about it. An isotonic fluid is nature's own nutrient delivery system.
Why is there left over powder in the cup after mixing with water?
Everyone's water is different; some tap water has a higher concentration of minerals and the pH level of water differs depending on geographic location and the quality of the tap water, which can lead to inconsistencies with the saturation point of a solution. To ensure that our solutions reach the point of saturation, regardless of the pH or mineral levels in water, we have maximized the formulation amounts so that every serving of Isotonix Calcium Plus contains the correct amount of calcium. The residue left in the cup is due to over-saturation which is common in tap water with a higher pH level or a higher mineral content.
What is the best way to store this product?
Keep Isotonix stored in a dry, cool place. If Isotonix are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator – but not in the fruit and vegetables area.
Isotonix® Calcium Plus Research Scope
43%
of U.S. adults do not meet daily calcium requirements from diet alone. (Source: National Institutes of Health, Office of Dietary Supplements).
700
Calcium is involved in the activation of over 700 enzymes essential for the body to function and age well.
65%
Bones are composed of about 65% mineral content, primarily calcium phosphate crystals, which give them strength and structure.
Reference List
- Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density on men and women 65 years of age and older. N Engl J Med. 1997; 337:670-676.
- Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997.
- Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res. 1994; 7:313-328.
- Hussain S, Ali SF. Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats. Neuroscience Letters. 1999; 261:21-24.
- Keen CL, Ensunsa JL, Watson MH, et al. Nutritional aspects of manganese from experimental studies. Neurotoxicol. 1999; 20:213-223.
- Martini LA. Magnesium supplementation and bone turnover. Nutr Rev. 1999; 57:227-229.
- Naghii MR, Wall PM, Samman S. The boron content of selected foods and the estimation of its daily intake among free-living subjects. J Am Coll Nutr. 1996 Dec;15(6):614-9.
- Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994;102:83-85
- Nielsen FH. Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9:61-69
- Nielsen FH. Ultratrace minerals. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins; 1999:283-303.
- Penland J.G. The importance of boron nutrition for brain and psychological function. Biol Trace Elem Res. 1998; 66:299-317.
- Saris N-EL, Mervaala E, Karppanen H, et al. An update on physiological, clinical and analytical aspects (review). Clinica Chimica Acta. 2000; 294:1-26.
- Shils ME. Magnesium. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:169-192.
- Singh MA. Combined exercise and dietary intervention to optimize body composition in aging. Ann N Y Acad Sci. 1998 Nov 20;854:378-93.
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA. 2000; 283:2822-2825.
- Strause L, Saltman P, Glowacki J. The effect of deficiencies of manganese and copper on osteo-induction and on resorption of bone particles in rats. Calcif Tissue Int. 1987; 41:145-150
- Sutherland B, Strong P, King JC. Determining human dietary requirements for boron. Biol Trace Elem Res. 1998 Winter;66(1-3):193-204.
- Volpe SL, Taper LJ, Meacham S. The relationship between boron and magnesium status and bone mineral density in the human: a review. Magnes Res. 1993;6:291-296
- Wargovich MJ, Eng VWS, Newmark HL. Calcium inhibits the damaging and compensatory proliferative effects of fatty acids on mouse colon epithelium. Cancer Lett. 1984; 23:253-258.
- Weaver CM, Heaney RP. Calcium. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:141-155.
- Zemel MB, Shi H, Greer B, et al. Regulation of adiposity by dietary calcium. FASEB J. 2000; 14:1132-1138.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Customer Rating
4.6 out of 5 star rating.
(104 reviews)
would recommend this product.
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Great product has no side effects. Good quality and price. Very happy.
Response from Customer Service on 05/12/2025
Thank you so much for your positive review of nutraMetrix Isotonix® Calcium Complete! We're delighted to hear that you are happy with the quality and value of the product. Your satisfaction means a lot to us, and we truly appreciate you taking the time to share your feedback. If you have any questions or need further assistance, please don’t hesitate to reach out. Thank you for choosing nutraMetrix Isotonix® Calcium Complete!
Where is it?
by LauriM
Shop Consultant
on 04/09/2025
Never showed up :(
Good
by Anonymous
on 02/18/2025
After taking the product you must drink water and get a bite to eat after two hours.
Response from Customer Service on 02/18/2025
Thank you for your review of Isotonix® Calcium Plus! We appreciate your tips on taking the product and ensuring a balanced approach. Your insights are valuable to us and help others get the most out of their experience. Thank you for being a part of our community and for choosing Isotonix®!
Ordering
by Anonymous
Verified Buyer
on 12/17/2024
Love the product hate your website. Takes 2 hours to order 3 things then when you place the order it changes your orders and duplicates it and your over charged for product you didn't want!!
I need you to cancel one of the Calcium Plus Isotonic! I only want one bottle!!! AND HOW DO YOU MAKE THEM AUTOSHIP?
Calcium
by Anonymous
on 10/22/2024
I've always loved this product. It allows greater absorption than traditional calcium pills.
Response from Customer Service on 10/22/2024
Thank you for your wonderful review of Isotonix® Calcium Plus! We're delighted to hear that you love the product and appreciate its benefits. Your feedback means a lot to us, and we're thrilled to be part of your daily routine. Thank you for choosing Isotonix!
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