Beyond Energy
Crafted for superior efficiency and optimal nutrient delivery.
All 8
Delivers 8 essential B vitamins. Each playing a critical role in supporting brain health, red energy and nervous system function.
10x
P5P (B6) is 10 times more bioavailable than standard pyridoxine hydrochloride (the common form of B6).
B-12
Delivers methylcobalamin, the neurologically active form of vitamin B12, to help support red blood cell formation, cognitive function, and methylation pathways essential for energy and nervous system health.

Folate* (Vitamin B9) (as (6S)-5-methyltetrahydrofolic calcium)
Supplies folate in its biologically active form, to help support methylation, neurotransmitter synthesis, homocysteine metabolism, and healthy cell division—foundational for cardiovascular function, cognitive health, and fetal development.

Vitamin B Complex: The Powerhouse of Energy
B-complex vitamins are foundational nutrients that power nearly every system in the body.
From cellular health to cognitive clarity, B vitamins play essential roles in maintaining overall vitality. When delivered in their bioactive forms, B-complex nutrients are considered even more effective—helping the body absorb and utilize them with ease. Whether you're seeking balanced energy, mental focus, or support for a busy lifestyle, a well-formulated B-complex can be a game-changing addition to daily wellness.

Product Classification

Good Manufacturing Practices

Isotonic

Gluten-Free

No Detectable GMO

Vegan

Dairy Free
Directions for Use

Pour one small capful (3.3 g) of Isotonix Activated B-Complex powder into your favorite cup.

Add 2 fl oz of water per capful and stir until fully dissolved.

Drink and enjoy! If mixed with other Isotonix products, add 2 oz of water for each capful.
Key Ingredients & Benefits

Niacinamide (Vitamin B3)*
Supports proper functioning of the digestive system, skin and nerves

Vitamin B12*
Increases energy and fuels optimal energy production
Promotes a healthy nervous system, bone marrow and intestinal tract

Folate (Vitamin B9)*
Promotes cardiovascular health
Promotes healthy levels of homocysteine

Vitamin B6 (P5P)*
Promotes normal cognitive performance
Maintains healthy levels of serotonin, thereby helping manage stress and support mood
Isotonix® Activated B Complex, The Vitamin B Advantage
Don't let a lack of B vitamins in your diet slow you down. Boost your B vitamins with our active forms of vitamins B6 and B12 and folate for increased energy and support of healthy levels of serotonin for healthy stress management. Don't just live-thrive with Isotonix!
Isotonix Delivery System

:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.

:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What does "Activated” refer to in Isotonix Activated B-Complex?
Activated refers to the active forms of vitamins B6, B12 and folic acid. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, there are circumstances in which this reaction is either slowed or inhibited.
What is the source of the vitamin B12 in our Isotonix Activated B-Complex?
Vitamin B-12 comes from bacteria. B12 in our diet can come from eggs or meats, or by taking a supplement. Vegetarians are recommended to take a B vitamin dietary supplement due to their lack of meat intake.
Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases and reduced levels of these vitamins have been associated with impaired cognitive performance, including vitamin B12. B12 plays a critical role in promoting normal energy production and nervous system function.
Is it toxic to take too much vitamin B12?
Vitamin B12 has not demonstrated any form of toxicity. As always, we only recommend the product to be taken as directed in the instructions.
What is the best way to store this product?
Keep Isotonix stored in a dry, cool place. If Isotonix are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator – but not in the fruit and vegetables area.
Isotonix® Activated B Complex Research Scope
20-25%
The percentage of women of reproductive age in the U.S. and Canada that have folate levels below the optimal range
86%
of vegetarians have low or deficient levels of vitamin B12 without supplementation.
20%
The percentage of adults that may have a subclinical deficiency in one or more B vitamins due to poor dietary intake.
Nearly 40%
of adults over 50 have decreased ability to absorb B12 from food due to lower stomach acid levels.
Reference List
- Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
- Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
- Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and
- Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
- Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
- combinations of folic acid and vitamin B12 on plasma homocysteine concentrations in healthy young women. Am J Clin Nutr 68:1104-10, 1998.
- Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
- Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
- Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4(4):249-265, 1999.
- Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise., 17(Supplement):287, 1985.
- Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
- Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
- van Oort FV, Melse-Boonstra A, Brouwer IA, et al. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. 77:1318-23, 2003.
- Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
- Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Customer Rating
4.5 out of 5 star rating.
(120 reviews)
would recommend this product.
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I'm completely obsessed with this product! It's my daily dose of energy that never wears off! Highly recommend!!!
Response from Customer Service on 02/24/2025
Thank you for your fantastic review of Isotonix® Activated B Complex! We're thrilled to hear that you're completely obsessed with it and that it provides you with a steady boost of energy. Your high recommendation means the world to us, and we’re delighted to be part of your daily routine. Thank you for choosing Isotonix, and for sharing your experience!
We always receive our products on time
by Anonymous
on 01/02/2025
Please call UFO services/Market America right away if you have waited over 10 days, dear customer.
Deliverey late
by WEI JIE (WENDY)C
on 12/16/2024
I ordered this product months ago, still did not receive it.
Isotonic Activated B Complex for low B5
by Anonymous
on 11/26/2024
Easy to prepare - like to drink vs pills
Response from Customer Service on 11/26/2024
Thank you for your review of Isotonix® Activated B Complex! We're delighted to hear that you find it easy to prepare and prefer the drinkable format over pills. Your convenience and preference mean a lot to us. Thank you for choosing our product and for sharing your positive experience!
Vitamin B
by FRANCISCOH
Shop Consultant
on 10/05/2024
I love this product been using it for 5 months and big difference it’s made in my health feeling energetic
Response from Customer Service on 10/07/2024
Thank you for your wonderful review of Isotonix® Activated B Complex! We're delighted to hear that you're experiencing increased energy and enjoying the benefits after using it for five months. Your satisfaction is our priority, and we're grateful for your trust in our product. If you have any questions or need assistance, we're here to help. Thank you for choosing us!
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