Isotonix OPC-3,Essential, Top 10 Customer Favorite, Vegetarian, Product Tested No Detectable GMO

$34.95 - $74.95

+ up to $1.50 / 2% Cashback

Feel Young and Stay Healthy with Isotonix OPC-3®

Results matter. With the unmatched 95% nutrient delivery of Isotonix OPC-3®, feel the life-changing difference in your energy, muscles and joint performance. 

Powered by Pycnogenol®—nature’s most powerful antioxidant—this formula aids oxygen delivery, fuels vital organs and combats signs of aging. Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed for your health and longevity!

Active Ingredients: Grape seed extract, pine bark extract (Pycnogenol®), red wine extract, bilberry extract, citrus bioflavonoid complex

Other ingredients: Fructose, glucose, citric acid, potassium bicarbonate, maltodextrin, silica, calcium sulfate, food starch (modified), apple pectin, stearic acid.   

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Formulated as the best antioxidant

Validated by research

20x

stronger than vitamin C

50x

stronger than vitamin E

95%

intestinal nutrient delivery for max absorption

Oligomeric proanthocyanadins (OPCs) are bioflavonoids (complex organic compounds) found in fruits, vegetables and certain tree barks that provide exceptional nutritional benefits to the human body.

The Super Antioxidant in OPC-3, Pycnogenol®‡

Isotonix OPC-3 contains the only isotonic form of Pycnogenol® in the world. Pycnogenol® is a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and potent bioflavonoid.

image of pinetree bark

Product Classification

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Gluten-Free

image of lab beaker

No Detectable GMO

image of glass containing liquid

Isotonic

image of Vegan

Vegan

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Good Manufacturing Practices

image of a bottle of milk with a line through it

Dairy Free

Directions for Use

Image of person pouring one level cap of Isotonix powder into cup

Pour 1 small capful (3.3 g) of powder into a cup.

Image of mixed Isotonix OPC-3 with water in cup.

Add water 2 fl. oz/60 mL of water for each capful and stir.

image of a woman holding a cup with mixed Isotonix OPC-3

Enjoy once a day. For maximum absorption take on an empty stomach.

Key Ingredients & Benefits

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Grape Seed Extract*

Maintains healthy cholesterol levels

image of red wine in a wooden spoon
Red Wine Extract*

Powerful antioxidant

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Bilberry Extract*

Powerful antioxidant
Supports healthy vision
Maintains healthy circulation

image of citrus fruits against a purple background
Citrus Extract (Bioflavaniods)*

Promotes cardiovascular health
Maintains healthy circulation

image of pine bark
Pycnogenol®†, Pine Bark Extract*

Supports the normal dialation of blood vessels
Provides complete antioxidant protection
Combats free radicals
Supports a healthy complexion
Promotes healthy sperm quality

World's Most Powerful Antioxidant

Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed to supercharge for health and longevity!

Isotonix Delivery System

:05 minutes

Isotonix Liquid Vitamins

  • Formulated to survive digestion.
  • Delivers concentrated nutrients to the site of absorption.
  • Contains no fillers or binders.
  • No artificial color or flavors. 

:40 minutes

Standard Vitamin Tablet

  • Contains lab-created coatings and lubricants.
  • Often contains artificial colors, nutrients and flavors.
  • Limited absorption of nutrient utilization. 

Frequently Asked Questions

Isotonix OPC-3 contains bioflavonoids, plant compounds that support cardiovascular health, healthy circulation and skin, joint and tissue integrity; it uses a unique Isotonix delivery system for fast, effective absorption and includes scientifically proven antioxidants to fight free radicals, making it one of the most powerful products available.

Thanks to its liquid, isotonic form, Isotonix OPC-3 is absorbed quickly by the small intestine, entering the bloodstream within minutes; this rapid absorption allows the body to benefit almost immediately.

Free radicals cause oxidative stress, which contributes to aging, circulation and heart and immune health. OPCs are powerful antioxidants — with more staying power than vitamins C and E — that help neutralize free radicals. Taking OPC-3 daily is essential for combating free radical damage and promoting health.

Even athletes experience free radical damage from increased oxygen use during exercise, which can affect muscle performance and endurance. Studies show OPCs promote endurance, reduce mild muscle cramps and support healthy blood flow, helping muscles recover and perform.

Yes, studies show OPCs can help mensural cramps.

Pycnogenol® is a patented extract from French maritime pine bark, supported by over 120 clinical studies; it acts as a powerful antioxidant, helping maintain healthy circulation, blood pressure and blood vessel function by promoting nitric oxide production.

Research Scope on OPC-3

558+

Studies on Pycnogenol® and Human Health

100

The number of active compounds found in Red Wine Extract

3

Independent studies for Isotonix OPC-3®

4x

The bioavailability of Isotonix OPC-3® compared to a tablet form

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.

Reviews

Customer Rating

4.6 out of 5 star rating.

(340 reviews)

Break down of ratings:
(282) 5 star ratings.
or, 83% of total reviews.
(26) 4 star ratings.
or, 8% of total reviews.
(12) 3 star ratings.
or, 4% of total reviews.
(4) 2 star ratings.
or, 1% of total reviews.
(16) 1 star ratings.
or, 5% of total reviews.
91%

would recommend this product.

Write a Review

Bring back the old see-through cap!

4 out of 5 star rating.

by Anonymous

on 06/17/2025

I have been taking OPC-3 for many years and I would not go without it. So the product is 5 stars, as many issues I used to deal with are gone - BUT the new cap is not at all good for measuring the water - you can hardly see the line for the 1 serving measurement. What was wrong with the previous caps? I agree with others who have the same issue. I'm saving my old caps, please bring them back! I also like the old label coloring on the bottles better than the new, as it was easier to differentiate the products. Why mess with a good thing?

Miracle Purple Powder

5 out of 5 star rating.

by ANGELES

Shop Consultant

on 06/03/2025

Isotonix OPC-3 is my top recommendation for those seeking convenient antioxidant support. The easy-to-mix powder and pleasant taste make it simple to add to any wellness routine.

Response from Customer Service on 06/04/2025

Thank you so much for your fantastic review of Isotonix OPC-3®! We’re delighted to hear how much you enjoy the convenience, taste, and how easily it fits into your wellness routine. Your recommendation means a great deal to us. Thank you for being a valued part of our community and for sharing your positive experience!

GAME CHANGER!!!!

5 out of 5 star rating.

by MichaelA

Shop Consultant

on 06/03/2025

"After consistently using OPC-3 for the past year, I’ve noticed positive changes in my energy, digestion, joint comfort, and overall well-being. It has truly become an important part of my daily wellness routine. For me, it’s been a game changer."

Response from Customer Service on 06/04/2025

Thank you so much for your enthusiastic review of Isotonix OPC-3®! We're thrilled to hear that you've experienced such positive changes and that OPC-3® has become an essential part of your daily wellness routine. Your feedback and support mean a lot to us. Thank you for being a valued member of our community and sharing your experience!

Love this stuff

5 out of 5 star rating.

by TimothyA

on 06/03/2025

Supports my wellness and tastes great. Easy to take.

Response from Customer Service on 06/04/2025

Thank you so much for your wonderful review of Isotonix OPC-3®! We’re happy to hear that you’re enjoying the taste and convenience, and that it supports your wellness. Your feedback means a lot to us—thank you for being a valued part of our community!

OPC-3

5 out of 5 star rating.

by PATTIL

Shop Consultant

on 06/03/2025

I’ve been using Isotonix OPC-3 for a few weeks and have noticed it supports my overall well-being. It’s easy to mix and has a pleasant taste. I like that it’s a convenient addition to my daily routine.

Response from Customer Service on 06/04/2025

Thank you so much for your thoughtful review of Isotonix OPC-3®! We’re happy to hear that you’re enjoying the convenience and taste of the product, and that it’s been a positive addition to your daily routine. Your feedback is greatly appreciated—thank you for choosing Isotonix OPC-3® and for being a valued member of our community!

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