• Promotes healthy muscle retention and use
• Aids in improving and enhancing memory
• Helps reduce muscle fatigue
• Supports cognitive performance
  
• Provides antioxidant protection to minimize the effects of free radicals that affect the aging process
• Helps support nerve function and blood flow in the heart

_{*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.}

No Detectable GMOs - The finished product contains no detectable genetically-modified organisms

Isotonic-Capable Drinkable Supplements - Easy-to-swallow supplements in liquid form are immediately available to the body for absorption

Quality Standards - GMP Operations and Standardized Ingredients

Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity

Prime Ultimate Longevity Formula by Isotonix is a powerful formula that specifically addresses the select needs of mature adults. While other products might focus on a particular area of aging, Prime Ultimate Longevity Formula by Isotonix is designed for the aging adult who wants to maintain both an alert mind and active body. Prime Ultimate Longevity Formula by Isotonix is formulated with natural ingredients, including huperzine A (which aids in improving and enhancing memory and cognitive function) and branched chain amino acids (which promote muscle retention).

Instantized Branched Chain Amino Acids 3000 mg
The branched chain amino acids (BCAA) in Prime Ultimate Longevity Formula by Isotonix have been instantized, meaning they have been developed through a unique production technology that allows for quicker dissolution in water and better bioavailability. BCAA are considered essential, as they cannot be synthesized by the human body and, therefore, must be consumed through diet or supplementation. Unlike other amino acids, BCAA are used primarily by skeletal muscle, making up 30-35 percent of the muscle tissue itself. These amino acids are important for muscle growth and retention and in the regulation of many cellular processes. As aging occurs, the body’s ability to build and retain muscle tissue or size is reduced, which can result in weakness and frailty. Research has shown that supplementation with BCAA promotes muscle retention in older adults. Additionally, it has been shown that supplementation of BCAA during exercise supports muscle protein synthesis, and inhibits protein catabolism (breakdown) and muscle fatigue. Studies indicate that BCAAs improve mental concentration, and reduce and delay mental fatigue. Though the exact mechanism by which BCAA affect mental performance is not known, it is hypothesized that by increasing blood levels of BCAA, the transport of tryptophan (causes relaxation/sleepiness) into the brain is balanced by competitive inhibition.

Grape Seed Extract (95% polyphenols) 100 mg
Grape seed extract has been shown to have antioxidant properties. Studies suggest that supplementing with grape seed extract can promote normal circulation. High in oligomeric proanthocyanidins (OPCs), grape seed extract is capable of decreasing and preventing the formation of free radicals which promote cardiovascular health. OPCs are also thought to promote healthy connective tissue and joint lubricant.

Huperzine A 100 mcg
Huperzine A is derived from the fir moss Huperzia serrata, also known as Chinese club moss. It appears to have some antioxidant capabilities. Studies on huperzine A have shown it to be effective for improving memory. Huberzine A helps support the neurotransmitter acetylcholine. Acetylcholine promotes normal learning, memory, cognitive well-being, healthy nerve transmission and proper muscle function. Huperzine A helps maintain normal concentration and promotes the duration of action of acetylcholine.

Potassium (bicarbonate) 300 mg
Foods rich in potassium include fresh vegetables and fruits such as bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery.

Potassium is stored in the muscles. Potassium is an essential macro mineral that helps to maintain fluid balance. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, it is important in the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids, the maintenance of intracellular tonicity and the maintenance of normal blood pressure. Potassium stimulates muscle relaxation and insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes proper heartbeat. Potassium is important in releasing energy from protein, fat and carbohydrates during metabolism. Potassium also regulates water balance and assists recuperative powers. Potassium is crucial for the elimination of wastes. Potassium is a natural pain desensitizer.

• Kimball, S. and Jefferson, L. Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis. Journal of Nutrition. 136(1): 227S-231S, 2006
• Miljkovic, D., et al. Calcium fructoborate: plant-based dietary boron for human nutrition. Journal of Dietary Supplements. 6(3): 211-226, 2009.
• Myers, T., et al. Systemic administration of the potential countermeasure huperzine reversibly inhibits central and peripheral acetylcholinesterase activity without adverse cognitive-behavioral effects. Pharmacology, Biochemistry and Behavior. 94: 477-481, 2010.
• Scorei,R., et al. In vitro effects of calcium fructoborate on fMLP-stimulated human neutrophil granulocytes. Biological Trace Element Research. 118 (1): 27-37, 2007.
• Scorei,R., et al. In vitro evaluation of the antioxidant activity of calcium fructoborate. Biological Trace Element Research. 107: 127-134, 2005.
• Shi, J., et al. Polyphenolics in grape seeds- biochemistry and functionality. Journal of Medicinal Food. 6(4): 291-299, 2003.
• Shimomura, Y., et al. Nutraceutical effects of branched-chain amino acids on skeletal muscle. Journal of Nutrition. 116(2): 529S-532S, 2006.
• Volpi, E., et al. Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. American Journal of Clinical Nutrition. 78: 250-258, 2003.

Other ingredients: Fructose, citric acid, malic acid, orange juice powder, orange flavor, silicon dioxide, rebaudioside A (stevia leaf), Lo Han (fruit) extract and stearic acid.

Contains: Soy, peanuts.

Directions for use: Pour 3 level, white bottle capfuls of powder into a cup. Add 6 fl. oz./180 mL (line on the overcap indicates 2 fl. oz./60 mL) of water and stir. As a dietary supplement, take once daily or as directed by your healthcare provider. Do not exceed 2 servings (6 capfuls) per day. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.

WARNING: If you are currently using anticholinergic drugs^‡, warfarin (Coumadin^®), other antiplatelet/anticoagulant drugs, levodopa, or any other prescription drugs, or have an ongoing medical condition, consult your healthcare provider before using this product. Women who are pregnant or breastfeeding should not use this product.

This supplement contains Huperzine A. Huperzine A is a reversible inhibitor of acetylcholinesterase and may cause cholinergic side effect. Caution should be used if you are taking drugs that promote or suppress acetylcholine activity.

This product contains no added wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.