Couldn't live without this!
5 out of 5 star rating. 
Transform food into energy!
100 mg
The multi-enzyme complex, DigeZyme® helps digest starch, cellulose fibers, fats, proteins and lactose sugar in dairy products.
150M
CFU of Lactospore® (bacillus coagulans) supports healthy balance of good bacteria in the gut.
Digestive Enzymes Found In DigeZyme®‡
DigeZyme® [Amylase, Protease, Cellulase, Lactase, Lipase] is a multienzyme that collectively supports the breakdown of complex macromolecules into energy sources and promotes the release of the nutrient content from the foods we eat.
Product Classification
Isotonic
Vegan
Dairy Free
Gluten-Free
No Detectable GMO
Good Manufacturing Practices
Directions For Use
Pour one small capful (3.3g) of Isotonix Digestive Enzymes with Probiotics into a cup.
Mix in 2 oz of water for each capful.
Take with or immediately following a meal for maximum benefits.
Key Ingredients & Benefits
Magnesium (Carbonate)*
Promotes normal synthesis of proteins
Supports cardiovascular health
Potassium (Bicarbonate)*
Helps maintain fluid balance
Contributes to a sense of well-being
Bacillus Coagulans (Lactospore®§)*
Produces good bacteria
Promotes digestive and gastrointestinal health
DigeZyme®‡ [Amylase, Protease, Cellulase, Lactase, Lipase]*
Promotes digestion and absorption of nutrients
Provides enzymes and good bacteria that promote the digestion and absorption of nutrients
Supports a healthy digestive tract
On-the-Go Digestive Support
Promote the absorption of nutrients. This digestive health promoting supplement features a formula of digestive enzymes and probiotics, including DigeZyme® — a blend of amylase, protease, cellulase, lactaase and lipase — and Lactospore® (bacillus coagulans) probiotic.
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What happens when we eat?
Digestion begins before we even eat — smelling food triggers saliva production. In the stomach, acid and enzymes break down food, which is further processed in the small intestine for nutrient absorption. The process continues in the large intestine, where nutrients are extracted.
What are digestive enzymes?
Digestive enzymes help break down food, improving the absorption of nutrients like proteins, starch, fats and sugars. They work in the gastrointestinal tract to support more efficient digestion.
What are the different types of digestive enzymes?
Protease breaks down proteins, amylase digests starch and lipase digests fats. Specialty enzymes like lactase, maltase, sucrase and cellulase help digest specific sugars and fibers, aiding in nutrient release.
What are probiotics?
Probiotics are beneficial bacteria that support digestive and immune health; they help maintain a healthy balance of gut bacteria. Isotonix Digestive Enzymes with Probiotics contains bacillus coagulans, a probiotic that produces lactic acid but isn’t classified as a lactic acid bacteria.
Research Scope
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
‡DigeZyme® is a registered trademark of the Sabinsa Corporation.
∅DU, PC, CU, LAC, FIP, and SU are units of enzyme activity.
§Lactospore® is a registered trademark of the Sabinsa Corporation.
¶CFU = colony-forming units.
Reviews
Break down of ratings: (24) 5 star ratings. (0) 4 star ratings. (0) 3 star ratings. (0) 2 star ratings. (0) 1 star ratings.
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I had a lot of digestive issues before Market America came out with this product. I was taking a separate protein powder, probiotics,
Since the Isitonix Digestive Enzyme with Probiotics came out it totally alleviates any fullness or discomfort when I eat! I couldn't recommend this enough! The small packet can get taken with you when you go OzuT to eat!!
Response from Customer Service on 06/18/2026
Thank you so much for sharing your experience! We’re delighted to hear how much Isotonix® Digestive Enzyme with Probiotics has benefited you and become an essential part of your routine. It’s great that you find the convenient packets easy to take with you on the go. Your recommendation means a lot to us—thank you for being a valued part of our community!
OMG Simply the Best
5 out of 5 star rating.
Digestive Enzymes have become a daily staple for me. I noticed that I simply feel more comfortable after meals and appreciate the support they provide as part of my wellness routine. They're easy to take and pair well with my other nutritional products. If digestive wellness is something you're focused on, these are worth considering.
Response from Customer Service on 06/15/2026
Thank you so much for your thoughtful review! We’re thrilled to hear that Isotonix® Digestive Enzyme with Probiotics has become an important part of your daily routine. It’s great to know you find them easy to use and a perfect fit alongside your other nutritional products. We truly appreciate your feedback and support, and we’re honored to be part of your wellness journey!
Best I have used!
5 out of 5 star rating.
Ive used all Market America Products since 1995.. I Highly recommend this great tasting one!
Response from Customer Service on 06/11/2026
Thank you so much for your wonderful review and long-term support of Market America products! We're delighted to hear you highly recommend Isotonix® Digestive Enzyme with Probiotics and enjoy its great taste. Your loyalty and feedback mean a lot to us. Thank you for being such a valued customer!
we all make bad food choices sometimes !
5 out of 5 star rating.
Thank you digestive enzymes for the rescue!  Takes the bloat and discomfort away!
Response from Customer Service on 06/08/2026
Thank you so much for your review of Isotonix® Digestive Enzyme with Probiotics! We're glad to hear it helps you feel better after those less-than-perfect food choices. Your feedback is greatly appreciated. Thank you for being a valued customer!
I take this product has 23 years,
5 out of 5 star rating.
I have take this product 23 years , I like it very much
Response from Customer Service on 05/27/2026
Thank you so much for your wonderful review and for your loyalty to Isotonix® Digestive Enzyme with Probiotics over the past 23 years! We’re delighted to hear how much you enjoy the product. Your continued support means a great deal to us. Thank you for being a valued customer!
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