Transform food into energy!
100 mg
The multi-enzyme complex, DigeZyme® helps digest starch, cellulose fibers, fats, proteins and lactose sugar in dairy products.
150M
CFU of Lactospore® (bacillus coagulans) supports healthy balance of good bacteria in the gut.
Digestive Enzymes Found In DigeZyme®‡
DigeZyme® [Amylase, Protease, Cellulase, Lactase, Lipase] is a multienzyme that collectively supports the breakdown of complex macromolecules into energy sources and promotes the release of the nutrient content from the foods we eat.
Product Classification
Isotonic
Vegan
Dairy Free
Gluten-Free
No Detectable GMO
Good Manufacturing Practices
Directions For Use
Pour one small capful (3.3g) of Isotonix Digestive Enzymes with Probiotics into a cup.
Mix in 2 oz of water for each capful.
Take with or immediately following a meal for maximum benefits.
Key Ingredients & Benefits
Magnesium (Carbonate)*
Promotes normal synthesis of proteins
Supports cardiovascular health
Potassium (Bicarbonate)*
Helps maintain fluid balance
Contributes to a sense of well-being
Bacillus Coagulans (Lactospore®§)*
Produces good bacteria
Promotes digestive and gastrointestinal health
DigeZyme®‡ [Amylase, Protease, Cellulase, Lactase, Lipase]*
Promotes digestion and absorption of nutrients
Provides enzymes and good bacteria that promote the digestion and absorption of nutrients
Supports a healthy digestive tract
On-the-Go Digestive Support
Promote the absorption of nutrients. This digestive health promoting supplement features a formula of digestive enzymes and probiotics, including DigeZyme® — a blend of amylase, protease, cellulase, lactaase and lipase — and Lactospore® (bacillus coagulans) probiotic.
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What happens when we eat?
Digestion begins before we even eat — smelling food triggers saliva production. In the stomach, acid and enzymes break down food, which is further processed in the small intestine for nutrient absorption. The process continues in the large intestine, where nutrients are extracted.
What are digestive enzymes?
Digestive enzymes help break down food, improving the absorption of nutrients like proteins, starch, fats and sugars. They work in the gastrointestinal tract to support more efficient digestion.
What are the different types of digestive enzymes?
Protease breaks down proteins, amylase digests starch and lipase digests fats. Specialty enzymes like lactase, maltase, sucrase and cellulase help digest specific sugars and fibers, aiding in nutrient release.
What are probiotics?
Probiotics are beneficial bacteria that support digestive and immune health; they help maintain a healthy balance of gut bacteria. Isotonix Digestive Enzymes with Probiotics contains bacillus coagulans, a probiotic that produces lactic acid but isn’t classified as a lactic acid bacteria.
Research Scope
Reference List
- Anonymous. Lactobacillus Sporogenes. Alternative Medical Review. 7(4): 340-342, 2002.
- Bourlioux, P., et al. The Intestine and Its Microflora are Partners for the Protection of the host: Report on the Danone Symposium “The Intelligent Intestine,” Held in Paris, June 14, 2002. American Journal of Clinical Nutrition. 78: 675-683, 2003.
- Casula, G. and Cutting, S. Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract. Applied and Environmental Microbiology. 68(5): 2344-2352, 2002.
- De Vecchi, E. and Drago, L. Lactobacillus Sporogenes or Bacillus Coagulans: Misidentification or Mislabeling? International Journal of Probiotics and Prebiotics. 1(1): 3-10, 2006.
- Feinle-Bisset, C., et al. Fat Digestion is Required for Suppression of Ghrelin and Stimulation of Peptide YY and Pancreatic Polypeptide Secretion by Intraduodenal Lipid. American Journal of Physiology: Endocrinology and Metabolism. 289: E948-E953, 2005.
- Lee, M., et al. Total Intestinal Lactase and Sucrase Activities Are Reduced in Aged Rats. Journal of Nutrition. 127(7): 1382-1387, 1997.
- Meisel, J. Commensal microbiota modulate gene expression in the skin. Microbiome. 6(1): 20, 2018
- Nichols, B., et al. The Maltase-Glucoamylase Gene: Common Ancestry to Sucrase-Isomaltase with Complementary Starch Digestion Activities. Proceedings of the National Academy of Sciences of the United States of America. 100(3): 1432-1437, 2003.
- O’Dea, K., et al. Rate of Starch Hydrolysis in Vitro as a Predictor of Metabolic Responses to Complex Carbohydrate In Vivo. American Journal of Clinical Nutrition. 34: 1991-1993, 1981.
- Sanders, M., et al. Sporeformers as Human Probiotics: Bacillus, Sporolactobacillus, and Brevibacillus. Comprehensive Reviews in Food Science and Food Safety. 2: 101- 110, 2003.
- Vaughn, A. R., et al. Skin-gut axis: The relationship between intestinal bacteria and skin health. World Journal of Dermatology. 6(4): 52-58, 2017
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
‡DigeZyme® is a registered trademark of the Sabinsa Corporation.
∅DU, PC, CU, LAC, FIP, and SU are units of enzyme activity.
§Lactospore® is a registered trademark of the Sabinsa Corporation.
¶CFU = colony-forming units.
Reviews
Customer Rating
5.0 out of 5 star rating.
(20 reviews)
would recommend this product.
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Customer Images
I have take this product 23 years , I like it very much
Response from Customer Service on 05/27/2026
Thank you so much for your wonderful review and for your loyalty to Isotonix® Digestive Enzyme with Probiotics over the past 23 years! We’re delighted to hear how much you enjoy the product. Your continued support means a great deal to us. Thank you for being a valued customer!
My product review.
by DEBRAF
Shop Consultant
on 05/12/2026
Oh my , what can I say about this digestive product. It works fast. I love it! Take it before a meal and you will be surprised at the non bloating after a meal. If you forget to take it before the meal and you are feeling bloated after a meal go a head and take it. The upset stomach immediately stops!
Response from Customer Service on 05/12/2026
Thank you so much for your enthusiastic review of Isotonix® Digestive Enzyme with Probiotics! We're delighted to hear how much you enjoy the product and that you've found it so helpful before and after meals. Your feedback is truly appreciated, and we're grateful that you've made Isotonix® a part of your routine. Thank you for being a valued customer!
Isotonix® Digestive Enzyme with Probiotics
by Anonymous
on 05/04/2026
after too much food , I feel indigestion, after 4 caps of enzyme with 8 oz water, wait for 1/2' hour, feel good.
Response from Customer Service on 05/05/2026
Thank you for taking the time to share your experience with Isotonix® Digestive Enzyme with Probiotics! We’re glad to hear that the product has become a helpful part of your routine, especially after enjoying a meal. Your feedback is greatly appreciated, and we hope Isotonix® continues to meet your needs. Thank you for being a valued customer!
Best digestive enzymes on the market. OP
by JohnG
Shop Consultant
on 04/29/2026
I’ve been taking this product for years. It’s a very effective and easy way to keep your digestive health in order. Would not go without it. It is especially great for those who have acid reflux problems.
Response from Customer Service on 04/29/2026
Thank you so much for your fantastic review and for being a loyal customer over the years! We're delighted to hear that Isotonix® Digestive Enzyme with Probiotics has been such an effective and easy addition to your routine. Thank you for your recommendation, please feel free to reach out for any assistance.
維持體重先清腸道
by Anonymous
on 04/23/2026
口味清新,尤如鮮檸水,喝完後清腸排毒,令我精神愉悅心情舒暢. 難得的好產品人人都需要.
Response from Customer Service on 04/24/2026
非常感謝您的精彩評價!我們很高興您喜歡 Isotonix® 益生菌消化酵素的清爽口感和提神功效。您的回饋對我們意義重大,感謝您成為我們社群的重要成員!
Thank you so much for your wonderful review! We're delighted to hear you enjoy the refreshing taste and uplifting benefits of Isotonix® Digestive Enzyme with Probiotics. Your feedback means a lot to us, thank you for being a valued member of our community!
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