One of the first products …
5 out of 5 star rating. 
Unlock the secret to healthy aging
250 mg
of Nicotinamide Riboside (NR)
50 mg
of the NAD precursor, Pterostilbene
The Core of Cellular Health
Nicotinamide Riboside (crystalline nicotinamide riboside chloride) NAD resides in every living cell in the body and has been strongly linked to keeping one's youth. NAD is the key to maintaining cellular metabolism, energy production and youthful vigor.
Product Classification
Vegan
No Detectable GMO
Gluten-Free
Good Manufacturing Practices
Key Ingredients & Benefits
Pterostilbene*
May help maintain NAD levels in aging adults
Supports healthy cognitive function
Helps to sustain neurological and cognitive health as we age
Promotes normal activity of the SIRT-1 gene
Protects the body from the negative effects of free radicals
Nicotinamide Riboside (crystalline nicotinamide riboside chloride)*
Supports healthy NAD production
Supports cellular health
Helps maintain healthy levels of ATP production within the cell
Supports healthy cellular metabolism
Helps potentially combat the cellular aging process
Fountain of Youth
Cutting-edge science that renews cells and DNA so you are energized and mentally sharp while looking and feeling younger. Whether fighting aging or coping with a demanding lifestyle, reclaim your spark and thrive with Prime NAD+!
Frequently Asked Questions
What factors influence NAD replenishment in cells?
NAD replenishment depends on its consumption and synthesis, maintained through the Preiss-Handler, de novo biosynthesis, and salvage pathways. NAD precursors like NR, NMN, NA, NAM, and tryptophan help boost levels, and foods like broccoli, avocado, and niacin-rich sources naturally support this process.
What depletes NAD levels besides aging?
Unhealthy habits like smoking, alcohol use, poor diet, lack of exercise, inadequate sleep, and being overweight can deplete NAD levels.
What is the half-life of pterostilbene compared to resveratrol?
Pterostilbene has a longer half-life (105 minutes) than resveratrol (14 minutes), providing longer-lasting effects.
How do Prime NAD+ and Heart Health Advanced Co-Q10 differ in supporting cells?
NAD+ sparks energy production by initiating ATP creation, essential for metabolism. Co-Q10 acts as fuel for mitochondria, protecting them from oxidative stress and supporting cardiovascular health. Prime NAD+ focuses on cellular energy and longevity, while Co-Q10 supports overall mitochondrial function.
How can sirtuin activity be promoted?
Sirtuin activity, linked to cell lifespan, can be boosted with NR, pterostilbene, resveratrol, curcumin, exercise, and caloric restriction.
What are telomeres?
Telomeres are protective caps at the ends of chromosomes that indicate cellular age. Maintaining healthy NAD and sirtuin activity supports telomere health, which declines as cells divide and age.
Prime NAD+ Research Scope
30+
Trillion cells in the body are fueled by the NAD molecule
500+
The number of enzymatic reactions fueled by NAD
50%
The rate of loss of NAD by the age of 50
4x
Pterostilbene has a bioavailability of 80% compared to resveratrol's 20%
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Break down of ratings: (35) 5 star ratings. (4) 4 star ratings. (0) 3 star ratings. (2) 2 star ratings. (1) 1 star ratings.
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This was one of the first products I purchased in the Core 3 Health trio! Anti aging help ! I feel better … My skin is better at almost 63 years old and that over all more energy push it gives me is second to none
Response from Customer Service on 06/04/2026
Thank you so much for your enthusiastic review of Prime Anti-Aging Nutraceuticals® NAD+! We're thrilled to hear it's made a positive impact on your routine and that you feel great, with noticeable improvements in your skin and energy. Your feedback is greatly appreciated. Thank you for being a valued customer and for choosing Prime NAD+ as part of your Core 3 Health trio!
My Age
5 out of 5 star rating.
This product has completely changed my life! I feel so much younger now that I've been taking this product!
Response from Customer Service on 05/21/2026
Thank you so much for sharing your wonderful experience with NAD+. We’re thrilled to hear how much it has positively impacted your life and helped you feel younger. Stories like yours inspire us every day! If you ever have any feedback or questions, please don’t hesitate to reach out—we’re always here for you. Cheers to feeling your best!
NAD
5 out of 5 star rating.
I would not be without this product! I have more focus & energy ! When I do run out, I notice a difference !
Response from Customer Service on 05/04/2026
Thank you so much for your wonderful review of Prime Anti-Aging Nutraceuticals® NAD+! We’re delighted to hear that you’ve noticed an improvement in focus and energy, and that this product has become an essential part of your routine. Your feedback means a lot to us, and we’re grateful for your continued support. Thank you for being a valued customer!
NAD question
4 out of 5 star rating.
I have heard that NAD is best taken as an IV and/or through the skin and is more effective through that method. Is the pill less effective because it has to go through digestion? Am I really getting a significant amount of NAD through a pill?
Response from Customer Service on 04/27/2026
Thank you so much for your thoughtful questions and for your interest in Prime Anti-Aging Nutraceuticals® NAD+!
There are a variety of ways to support NAD+ levels in the body, including IV, transdermal (through the skin), and oral supplementation such as pills or capsules. While IV and transdermal methods may offer different forms of absorption, high-quality oral supplements are formulated to deliver effective amounts that can be absorbed during the digestive process.
Prime NAD+ is formulated with one of NAD’s key precursors, nicotinamide riboside (NR). The effect is still the same, which is to naturally boost NAD stores within the cell. Both NR and NMN are forms that your body can absorb and convert to NAD inside your cells. It’s important to note that NAD itself is a large molecule and is poorly absorbed when taken directly, even at high milligram amounts, which is why using these precursors offers a more effective solution for supporting your NAD+ levels.
Prime NAD+ is carefully designed with bioavailable ingredients and produced to meet the highest standards, so you can be confident in its effectiveness as part of your wellness routine. While the digestive process does play a role in absorption, clinical studies show that oral NAD+ precursors like NR can significantly support your body’s NAD+ levels.
If you have any specific health concerns or are considering combining multiple approaches, we always recommend consulting with your healthcare provider. Thank you again for your questions! If you need more information or have additional questions, please let us know—we're here to help.
NAD. is great.
5 out of 5 star rating.
I take it every morning and it gives me lots of energy and not side effects.
Response from Customer Service on 04/27/2026
Thank you so much for your great review! We're delighted to hear that Prime Anti-Aging Nutraceuticals® NAD+ has been a positive addition to your morning routine and helps you feel energized. Your feedback means a lot to us—thank you for being a valued member of our community!
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