The Single Most Influential Mineral
300
Magnesium supports more than 300 enzymes in the body that are crucial for a health and energy.
4th
Magnesium is the fourth most abundant mineral in the body.
2
Formulated with two highly bioavailable forms of magnesium for superior absorption and function.

The Mighty Magnesium, Citrate & Glycinate
Adequate magnesium intake plays a vital role in supporting cognitive health, including concentration, memory and overall mental clarity. In contrast, low magnesium levels have been associated with decreased focus, reduced cognitive performance, muscle discomfort and poor sleep quality. Isotonix® Magnesium is expertly formulated with two highly absorbable forms of magnesium — citrate and glycinate — to maximize bioavailability and support optimal absorption. Each serving delivers 100% of the recommended daily value, helping you maintain healthy magnesium levels for cognitive support, muscle relaxation and restful sleep.

Product Classification

Good Manufacturing Practices

No Detectable GMO

Isotonic

Vegan

Dairy Free

Gluten-Free
It's More than Just an Electrolyte Booster
Magnesium is essential for a healthy lifestyle! Working in harmony with calcium, it helps regulate your heart and maintain normal blood pressure. But that’s not all—magnesium also supports your body’s ability to build strong bones and teeth and promotes proper muscle development. When combined with calcium and vitamin D, magnesium helps keep your bones resilient and healthy, so you can stay active and feel your best every day!

Key Ingredients & Benefits

Magnesium Glycinate*
Supports a healthy sleep quality
Promotes cognitive health and head comfort
Helps maintain normal blood pressure

Magnesium Citrate*
Supports cardiovascular health and bone health
Promotes optimal muscle health
Helps maintain normal blood sugar levels

Potassium (Bicarbonate)*
Promotes a normal heartbeat
Supports a wide variety of biochemical and physiological processes
Supports the normal transmission of nerve impulses and the contraction of cardiac, skeletal and smooth muscle
Supports the body’s ability to regulate water balance, recover from exercise and eliminate wastes
Unlock Your Body's Full Potential
Experience more than just an electrolyte booster. Unlike the magnesium we acquire from food, our highly bioavailable formula ensures superior absorption for faster, noticeable results. Feel the difference with Isotonix Magnesium!
Directions For Use

Pour one small capful (3.3 g) of Isotonix Magnesium into your favorite cup.

Add 2 fl oz of water for each capful and mix.

For best results, take twice daily — one capful in the morning and evening. If mixed with other Isotonix products, add 2 oz of water for each capful.
Isotonix Delivery System

:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.

:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What benefits does magnesium provide for the body?
With its involvement in supporting over 300 enzyme reactions, magnesium plays roles in many aspects of health. With regards to bone health, it is an important component of the mineralized part of bone and supports the normal metabolism of calcium and potassium in adults. Magnesium works together with calcium and vitamin D to help keep bones strong and support bone mineral density. Magnesium also supports muscle development and movement and the transmission of nerve impulses to the muscles. Studies clearly demonstrate the effects of supplemental magnesium on muscular health. Adequate magnesium levels are also important for cardiovascular health. Studies show magnesium supports a regular heartbeat, thus promoting a healthy heart. Additionally, magnesium helps maintain normal blood pressure. Magnesium supports normal protein synthesis. As such, there is evidence that magnesium helps maintain normal blood sugar levels.
How much magnesium should I be getting, and why do I need a magnesium supplement versus getting it from my normal diet?
The recommended daily intake for adults, established by the Institute of Medicine of the National Academy of Sciences, states that adult males between the ages of 19 and 30 should be receiving 400 mg of magnesium daily. Adult females of the same age should receive 310 mg daily. For older males, the recommendation is 420 mg daily, while older females should consume 320 mg daily. Daily lifestyle factors and poor dietary choices adversely affect the amount of magnesium we are ingesting. Foods rich in magnesium include whole grains, nuts and green vegetables, which are potent sources of magnesium because of their chlorophyll content. Meats, starches, dairy products and refined and processed foods — which make up a large portion of the typical diet in today’s society — contain low amounts of magnesium.
What is the Isotonix delivery system, and how does it work?
Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state. When an isotonic substance enters the body, it will be absorbed into the bloodstream rapidly. Isotonix dietary supplements are delivered in an isotonic solution, allowing nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
Does this product need to be taken on an empty stomach?
Yes. For maximum absorption, the product should be taken on an empty stomach.
What other health and nutrition products would complement Isotonix Magnesium?
The benefits of Isotonix Magnesium are complemented by Isotonix OPC-3®, Isotonix Calcium Plus, Isotonix Vitamin D with K2 and Heart Health™ Omega III Fish Oil with Vitamin E.
What is the best way to store this product?
Keep Isotonix products stored in a dry, cool place. If Isotonix products are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator — but not in the fruit and vegetables area.
Isotonix® Magnesium Research Scope
290 mg
A study published in the Journal of Nutrition found that most U.S. adults — especially those over the age of 30 — were receiving, on average, approximately 290 mg of magnesium daily.
400 mg
According to the Institute of Medicine of the National Academy of Sciences, adult males between 19-30 should receive as much as 400 mg of magnesium daily.
310 mg
According to the Institute of Medicine of the National Academy of Sciences, adult females between 19-30 should receive as much as 310 mg of magnesium daily.
Reference List
- Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. National Academy Press. Washington, DC, 1999.
- Wester PO. Magnesium. Am J Clin Nutr. 45:1305-12, 1987.
- Saris NE, Mervaala E, et al. Magnesium: an update on physiological, clinical, and analytical aspects. Clinica Chimica Acta. 294:1-26, 2000.
- Vormann J. Magnesium: nutrition and metabolism. Molecular Aspects of Medicine. 24:27-37, 2003.
- Rude KR. Magnesium metabolism and deficiency. Endocrinol Metab Clin North Am. 22:377-95, 1993.
- Kobrin SM and Goldfarb S. Magnesium Deficiency. Semin Nephrol.10:525-35, 1990.
- Kobrin SM and Goldfarb S. Magnesium Deficiency. Semin Nephrol. 10:525-35, 1990.
- Sinclair, S., et al. Migraine headaches: nutritional, botanical and other alternative approaches. Alternative Medicine Review. 4(2):86-95, 1999.
- Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PW, Kiel DP. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr. 69(4):727-36, 1999.
- Tranquilli AL et al. Calcium, phosphorus and magnesium intakes correlate with bone mineral content in postmenopausal women. Gynecol Endocrinol. 8:55-8, 1994.
- Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. National Academy Press. Washington, DC, 1999.
- New SA et al. Nutritional influences on bone mineral density: a cross-sectional study in premenopausal women. Am J Clin Nutr. 65:1831-9, 1997.
- Gruber H et al. Magnesium deficiency: effect on bone mineral density in the mouse appendicular skeleton. BMC Musculoskelet Disord. 4(1):7, 2003.
- Ryder K et al. Magnesium intake from food and supplements is associated with bone mineral density in healthy older white subjects. J Am Geriatr Soc. 53(11):1875-1880, 2005.
- Bilbey, D.L. J., et al. Muscle cramps and magnesium deficiency: case reports. Can Fam Physician. 42:1348-51, 1996.
- Dahle, L. O., et al. The effect of oral magnesium substitution on pregnancy-induced leg cramps. Am J Obstet Gynecol. 173(1):175-180, 1995.
- Saris, N.-E. L., et al. Magnesium: an update on physiological, clinical and analytical aspects. Clinica Chimica Acta. 294:1-26, 2000.
- Yu-Yahiro, J. A. Electrolytes and their relationship to normal and abnormal muscle function. Orthop Nurs. 13(5):38-40, 1994.
- Brilla, L. R., et al. Effect of magnesium supplementation on strength training in humans. J Am Coll Nutr. 11(3):326-329, 1992.
- Chollet D et al. Blood and brain magnesium in inbred mice and their correlation with sleep quality. Am J Physiol Regul Integr Comp Physiol. 279(6):R2173-8, 2000.
- Sato-Mito N et al. The midpoint of sleep is associated with dietary intake and dietary behavior among young Japanese women. Sleep Med. 12(3):289-94, 2011.
- Saris, N.-E. L., et al. Magnesium: an update on physiological, clinical and analytical aspects. Clinica Chimica Acta. 294:1-26, 2000.
- Huskisson E et al. The influence of micronutrients on cognitive function and performance. J Int Med Res. 35(1):1-19, 2007. Review.
- Inna Slutsky et al. Enhancement of Learning and Memory by Elevating Brain Magnesium. Neuron. 65(2):165-77, 2010.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Customer Rating
4.7 out of 5 star rating.
(79 reviews)
would recommend this product.
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Have the ingredients changed since you changed the design of the label? I’m not getting the same sleep results since buying this new design bottle.
Response from Customer Service on 03/20/2025
Thank you for reaching out with your concern about Isotonix® Magnesium. We want to assure you that while the label design has been updated, the formula itself has not changed. The ingredients remain the same, providing the consistent quality and benefits you expect.
It's important to note that noticeable effects can vary due to various factors such as individual gut health, stress levels, and overall lifestyle choices. We understand how essential the product's effects are to you and appreciate your trust in us. If you have any further questions or need assistance, please don't hesitate to contact us. Thank you for choosing Isotonix® and for sharing your experience with us!
taste and dissolve
by Anonymous
on 03/01/2025
Actually I use Isotonix OPC3 for few years long , on-off and have introduced to quite a few friends. My cousin who's 90 yrs now, she loves it because she can eat and sleep well. Taking it when exhausted youI can feel how amazing it is after 15 minutes!!!
But this is my first time using Isotonix Magnesium with hope for my leg cramp matter:
- I love the taste and smell, very easy to drink
- I have a question about it's dissolving capable: I measure 1 full cap in to a 60ml water cup, stir for a while but there's still some stubborn white granules stay at bottom. I drink the clear top then add more water, stir more but even after few hrs...nothing changes. Scared!!! Of course I discarded that portion. May I have an answer for this problem?
Response from Customer Service on 03/03/2025
Thank you for your continued loyalty to Isotonix OPC-3 and for introducing it to your friends and family! We're thrilled to hear about the positive change it has had for you and your cousin, especially in terms of well-being and vitality.
Regarding your experience with Isotonix Magnesium, we're glad to hear you find the taste and smell appealing. As for the dissolving process, the white granules you've noticed are typically undissolved minerals, such as calcium and magnesium, which naturally dissolve slower. Another possible factor is silica, an FDA-confirmed food-grade ingredient that helps keep the powder free-flowing.
The dissolution time can be influenced by the temperature and type of water used. For instance, mineral water and water with a higher sediment content, especially from filters that might need changing, can affect how well the minerals dissolve. We recommend swirling the particles and consuming them, as they can still be absorbed effectively by the gut.
We understand your concern and appreciate your inquiry. Rest assured, you're not the only one who has noticed this, and the particles are safe to consume. Thank you for reaching out, and for choosing Isotonix.
I was sound asleep!!
by TEDDYG
Shop Consultant
on 12/20/2024
I received this product on Dec 18, and I took it at night before I went to bed. Little did I know, I was knocked out lol. One word 'WOW'
Response from Customer Service on 12/20/2024
Thank you for your enthusiastic review of Isotonix® Magnesium! We're thrilled to hear that it has made such a positive impression from your very first experience. Your "WOW" tells us everything we need to know, and we're delighted to be a part of your nightly routine. Thank you for choosing Isotonix and for sharing your experience with us—it's truly appreciated!
Energy and Sleep!
by PamelaS
Shop Consultant
on 12/02/2024
Taking magnesium in the morning gives me energy. Taking it before bed helps me sleep soundly through the night
Response from Customer Service on 12/02/2024
Thank you for sharing your experience with magnesium! We're delighted to hear that it provides you with energy during the day and restful sleep at night. It's wonderful to know that it supports your well-being so effectively.
this one is a must!
by AubreyL
Shop Consultant
on 11/08/2024
I love this product, it helps me feel my best during the day and at night. I use a cap right before bedtime and its a natural way to wind down after a long day. Such a great value and always have this in our house.
Response from Customer Service on 11/11/2024
Thank you for your lovely review of Isotonix® Magnesium! We're delighted to hear that it helps you feel your best and provides a natural way to wind down after a long day. Your feedback and continued support mean a lot to us. Thank you for choosing our product and for making it a staple in your home!
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