I love this product but...
3 out of 5 star rating. 
Beyond Energy
Crafted for superior efficiency and optimal nutrient delivery.
All 8
Delivers 8 essential B vitamins. Each playing a critical role in supporting brain health, red energy and nervous system function
10x
P5P (B6) is 10 times more bioavailable than standard pyridoxine hydrochloride (the common form of B6)
B12
Delivers methylcobalamin, the neurologically active form of vitamin B12, to help support red blood cell formation, cognitive function and methylation pathways essential for energy and nervous system health
Folate* (Vitamin B9) (as (6S)-5-methyltetrahydrofolic calcium)
It supplies folate in its biologically active form to help support methylation, neurotransmitter synthesis, homocysteine metabolism and healthy cell division — foundational for cardiovascular function, cognitive health and fetal development.
Product Classification
Good Manufacturing Practices
Isotonic
Gluten-Free
No Detectable GMO
Vegan
Dairy Free
Vitamin B Complex: The Powerhouse of Energy
B-complex vitamins are foundational nutrients that power nearly every system in the body.
From cellular health to cognitive clarity, B vitamins play essential roles in maintaining overall vitality. When delivered in their bioactive forms, B-complex nutrients are considered even more effective — helping the body absorb and utilize them with ease. Whether you're seeking balanced energy, mental focus or support for a busy lifestyle, a well-formulated B-complex vitamin can be a game-changing addition to daily wellness.
Key Ingredients & Benefits
Niacinamide (Vitamin B3)*
Supports proper functioning of the digestive system, skin and nerves
Vitamin B12*
Increases energy and fuels optimal energy production
Promotes a healthy nervous system, bone marrow and intestinal tract
Folate (Vitamin B9)*
Promotes cardiovascular health
Promotes healthy levels of homocysteine
Vitamin B6 (P5P)*
Promotes normal cognitive performance
Maintains healthy levels of serotonin, thereby helping manage stress and support mood
Isotonix Activated B Complex — The Vitamin B Advantage
Don't let a lack of B vitamins in your diet slow you down. Boost your B vitamins with our active forms of vitamins B6 and B12 and folate for increased energy and support of healthy levels of serotonin for healthy stress management. Don't just live, thrive with Isotonix®!
Directions for Use
Pour one small capful (3.3 g) of Isotonix® Activated B-Complex powder into your favorite cup.
Add 2 fl oz of water per capful and stir until fully dissolved.
Drink and enjoy! If mixed with other Isotonix products, add 2 oz of water for each capful.
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What does "Activated” refer to in Isotonix® Activated B Complex?
Activated refers to the active forms of vitamins B6 and B12 and folic acid. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, but there are circumstances when this reaction is either slowed or inhibited.
What is the source of the vitamin B12 in Isotonix Activated B Complex?
Vitamin B12 comes from bacteria. B12 in our diet can come from eggs or meats, or by taking a supplement. Vegetarians are recommended to take a B vitamin dietary supplement due to their lack of meat intake.
Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases and reduced levels of these vitamins have been associated with impaired cognitive performance, including vitamin B12. B12 plays a critical role in promoting normal energy production and nervous system function.
Is it toxic to take too much vitamin B12?
Vitamin B12 has not demonstrated any form of toxicity. As always, we only recommend the product to be taken as directed in the instructions.
What is the best way to store this product?
Keep Isotonix stored in a cool, dry place. If Isotonix products are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator — but not in the area for fruits and vegetables.
Research Scope
20-25%
of women of reproductive age in the U.S.A. and Canada have folate levels below the optimal range.
86%
of vegetarians have low or deficient levels of vitamin B12 without supplementation.
20%
of adults that may have a subclinical deficiency in one or more B vitamins due to poor dietary intake.
Nearly 40%
of adults over 50 have decreased ability to absorb B12 from food due to lower stomach acid levels.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Break down of ratings: (110) 5 star ratings. (4) 4 star ratings. (7) 3 star ratings. (4) 2 star ratings. (7) 1 star ratings.
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Can you tell me why Maltodextrin is used in these amazing supplements?
Maltodextrin is NOT a healthy component of any supplement:
(AI Overview)
Maltodextrin isn't inherently toxic, but it is a highly processed, high-glycemic carbohydrate. It provides empty calories and can cause blood sugar spikes, digestive discomfort, and gut flora imbalances. People with diabetes, insulin resistance, or sensitive digestive systems should generally avoid or limit it.
MDVIP
+2
Maltodextrin is a polysaccharide made from starch (typically corn, rice, or wheat) and is used as a cheap thickener or filler in packaged goods.
Response from Customer Service on 07/09/2026
Thank you for your feedback on the Isotonix® Activated B Complex!
The maltodextrin used in the Isotonix line is a premium source which allows us to maintain the quality of a tested no GMO detected product. The ingredient is second to none. The maltodextrin in Isotonix is both nutritive and functional. We use a maltodextrin with a low dextrose equivalent (DE) to ensure that the product ingredients do not interact with each other while also limiting the glycemic impact of the sugars.
We will send you even more scientific information via email so that you will know you can feel comfortable consuming it!
Isotonix Vitamin B
5 out of 5 star rating.
Within 15 minutes of taking my Vitamin B, especially in the later afternoon, my energy level definitely steps up. I have been using this supplement for over 25 years and take 2-3 caps daily. Love our Isotonix!
Response from Customer Service on 06/22/2026
Thank you so much for your wonderful feedback and for being such a loyal supporter of Isotonix® Activated B Complex for over 25 years! We’re thrilled to hear it continues to give you the boost you’re looking for, especially when you need it most. Your enthusiasm means so much to us. Thank you for making Isotonix a part of your daily routine and for being part of our community!
Great alternative to afternoon coffee!
5 out of 5 star rating.
I love having this on hand when I'm at work, in the small bottle. I need a little boost, instead of coffee which may effect my sleeping that night, a quick shot of the B complex works for me in minutes. Unlike caffeine, I just feel awake, alert. No longer sleepy. And I can drink it later in the day and not worry about not being able to get to sleep, like with coffee or energy drinks. Healthy eneregy!
Response from Customer Service on 06/15/2026
Thank you so much for your wonderful review of Isotonix® Activated B Complex! We're glad to hear it provides a healthy energy boost and helps you stay awake and alert without affecting your sleep. Your feedback about the convenience and benefits is greatly appreciated. Thank you for being a valued customer!
I love Activated B complex on a daily basis!!!!
5 out of 5 star rating.
I love B complex because it promotes normal cognitive performance and I believe lots of people are looking for a way to help manage stress and support mood! The best!
Response from Customer Service on 06/08/2026
Thank you so much for your fantastic review of Isotonix® Activated B Complex! We're thrilled to hear you appreciate its support for cognitive performance, stress management, and mood. Your feedback means a lot to us. Thank you for being a valued customer!
10/10
5 out of 5 star rating.
我先生服用了两年多等渗B族维生素后，改善了身体机能和精神状态，他非常喜欢👍会持续服用
Response from Customer Service on 03/03/2026
非常感谢您的精彩评价！我们很高兴得知您的丈夫喜欢 Isotonix® 活性 B 族维生素，并从中受益匪浅。您的反馈和持续支持对我们意义重大——感谢您成为我们社区的重要成员！
Thank you so much for your fantastic review! We're delighted to hear that your husband has enjoyed Isotonix® Activated B Complex and that he has experienced such positive benefits with it. Your feedback and continued support mean a lot to us—thank you for being a valued part of our community!
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