10/10
5 out of 5 star rating. 
Beyond Energy
Crafted for superior efficiency and optimal nutrient delivery.
All 8
Delivers 8 essential B vitamins. Each playing a critical role in supporting brain health, red energy and nervous system function
10x
P5P (B6) is 10 times more bioavailable than standard pyridoxine hydrochloride (the common form of B6)
B12
Delivers methylcobalamin, the neurologically active form of vitamin B12, to help support red blood cell formation, cognitive function and methylation pathways essential for energy and nervous system health
Folate* (Vitamin B9) (as (6S)-5-methyltetrahydrofolic calcium)
It supplies folate in its biologically active form to help support methylation, neurotransmitter synthesis, homocysteine metabolism and healthy cell division — foundational for cardiovascular function, cognitive health and fetal development.
Product Classification
Good Manufacturing Practices
Isotonic
Gluten-Free
No Detectable GMO
Vegan
Dairy Free
Vitamin B Complex: The Powerhouse of Energy
B-complex vitamins are foundational nutrients that power nearly every system in the body.
From cellular health to cognitive clarity, B vitamins play essential roles in maintaining overall vitality. When delivered in their bioactive forms, B-complex nutrients are considered even more effective — helping the body absorb and utilize them with ease. Whether you're seeking balanced energy, mental focus or support for a busy lifestyle, a well-formulated B-complex vitamin can be a game-changing addition to daily wellness.
Key Ingredients & Benefits
Niacinamide (Vitamin B3)*
Supports proper functioning of the digestive system, skin and nerves
Vitamin B12*
Increases energy and fuels optimal energy production
Promotes a healthy nervous system, bone marrow and intestinal tract
Folate (Vitamin B9)*
Promotes cardiovascular health
Promotes healthy levels of homocysteine
Vitamin B6 (P5P)*
Promotes normal cognitive performance
Maintains healthy levels of serotonin, thereby helping manage stress and support mood
Isotonix Activated B Complex — The Vitamin B Advantage
Don't let a lack of B vitamins in your diet slow you down. Boost your B vitamins with our active forms of vitamins B6 and B12 and folate for increased energy and support of healthy levels of serotonin for healthy stress management. Don't just live, thrive with Isotonix®!
Directions for Use
Pour one small capful (3.3 g) of Isotonix® Activated B-Complex powder into your favorite cup.
Add 2 fl oz of water per capful and stir until fully dissolved.
Drink and enjoy! If mixed with other Isotonix products, add 2 oz of water for each capful.
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
What does "Activated” refer to in Isotonix® Activated B Complex?
Activated refers to the active forms of vitamins B6 and B12 and folic acid. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, but there are circumstances when this reaction is either slowed or inhibited.
What is the source of the vitamin B12 in Isotonix Activated B Complex?
Vitamin B12 comes from bacteria. B12 in our diet can come from eggs or meats, or by taking a supplement. Vegetarians are recommended to take a B vitamin dietary supplement due to their lack of meat intake.
Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases and reduced levels of these vitamins have been associated with impaired cognitive performance, including vitamin B12. B12 plays a critical role in promoting normal energy production and nervous system function.
Is it toxic to take too much vitamin B12?
Vitamin B12 has not demonstrated any form of toxicity. As always, we only recommend the product to be taken as directed in the instructions.
What is the best way to store this product?
Keep Isotonix stored in a cool, dry place. If Isotonix products are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator — but not in the area for fruits and vegetables.
Research Scope
20-25%
of women of reproductive age in the U.S.A. and Canada have folate levels below the optimal range.
86%
of vegetarians have low or deficient levels of vitamin B12 without supplementation.
20%
of adults that may have a subclinical deficiency in one or more B vitamins due to poor dietary intake.
Nearly 40%
of adults over 50 have decreased ability to absorb B12 from food due to lower stomach acid levels.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Break down of ratings: (107) 5 star ratings. (4) 4 star ratings. (6) 3 star ratings. (4) 2 star ratings. (7) 1 star ratings.
would recommend this product.
Select sort by
Customer Images
我先生服用了两年多等渗B族维生素后，改善了身体机能和精神状态，他非常喜欢👍会持续服用
Response from Customer Service on 03/03/2026
非常感谢您的精彩评价！我们很高兴得知您的丈夫喜欢 Isotonix® 活性 B 族维生素，并从中受益匪浅。您的反馈和持续支持对我们意义重大——感谢您成为我们社区的重要成员！
Thank you so much for your fantastic review! We're delighted to hear that your husband has enjoyed Isotonix® Activated B Complex and that he has experienced such positive benefits with it. Your feedback and continued support mean a lot to us—thank you for being a valued part of our community!
Got Stress? Find relief
5 out of 5 star rating.
Activated Isotonix Bcomplex was the first supplement I tried 26 years ago. Working long hours and being present for our 2 young children, it was important I maintained a patient mood, had energy, and could focus. Within 10 minutes of drinking my Isotonix after work (before kiddos) it supported relaxation and relief so I could be the mom I wanted to be for my children.
Response from Customer Service on 02/28/2026
Thank you so much for sharing your wonderful experience and for being a long-time supporter of Isotonix® Activated B Complex! We’re thrilled to hear the difference it’s made in your daily routine and how it’s supported you in being present for your family. Your feedback means a lot to us—thank you for being a valued member of our community!
My product review
5 out of 5 star rating.
I have been taking for many years but the last bottle I got had lumps in the bottle like it had been placed in a humid area and I called my Isotonix representative and told her about it and she said she would have someone call but no one called. The bottle was hard to measure out with all the lumps in the bottle of the product. I was hoping I would have heard back and possibly offered a free bottle but nothing
Response from Customer Service on 02/11/2026
Thank you so much for your feedback and for being a longtime user of Isotonix® Activated B Complex. We sincerely apologize for the inconvenience you experienced with your recent bottle. Clumping can sometimes occur due to exposure to moisture or temperature changes, and we understand how this can affect your experience.
We appreciate your patience and want to ensure your concerns are addressed. A product specialist will reach out to you directly to further assist. Thank you for bringing this to our attention, and for your continued support as a valued member of our community.
My product review
5 out of 5 star rating.
I have been taking for many years but the last bottle I got had lumps in the bottle like it had been placed in a humid area and I called my Isotonix representative and told her about it and she said she would have someone call but no one called. The bottle was hard to measure out with all the lumps in the bottle of the product. I was hoping I would have heard back and possibly offered a free bottle but nothing
Response from Customer Service on 02/11/2026
Thank you so much for your feedback and for being a longtime user of Isotonix® Activated B Complex. We sincerely apologize for the inconvenience you experienced with your recent bottle. Clumping can sometimes occur due to exposure to moisture or temperature changes, and we understand how this can affect your experience.
We appreciate your patience and want to ensure your concerns are addressed. A product specialist will reach out to you directly to further assist. Thank you for bringing this to our attention, and for your continued support as a valued member of our community.
Better B - Better Z's....
5 out of 5 star rating.
I sleep so much better now because of this formulate b-complex. Thank you Shop.com/Market America for having such high-end yet affordable products.
Response from Customer Service on 12/23/2025
Thank you so much for your wonderful feedback on Isotonix® Activated B Complex! We’re delighted to hear that you’re enjoying the benefits of our product. Your kind words about the quality and affordability of our products mean a lot to us. Thank you for choosing Shop.com and Market America, and for being a valued customer!
View Customer Images 
