All the products I order are great
5 out of 5 star rating. 
Fortify Your Calcium Intake
5 Salts
Unlike most calcium products that rely on just one or two basic forms, this advanced blend features five distinct calcium salts, each selected for their superior bioavailability and complementary health benefits.
375 mg
of calcium in one serving of Isotonix® Calcium Plus. While leafy greens are healthy, supplements can ensure consistent and bioavailable calcium intake — especially for those with increased needs.
Charge Up with Calcium
Calcium is a cornerstone of everyday health, and Isotonix® Calcium Plus is designed to deliver it better. Our advanced formula blends multiple bioavailable calcium salts in an isotonic form — helping it remain in a charged, ready-to-absorb state as it moves through your body. The result? Faster uptake, better utilization and stronger support for the life you live today and tomorrow. It's calcium, elevated.
Product Classification
Good Manufacturing Practices
Isotonic
Gluten-Free
No Detectable GMO
Vegetarian
Dairy Free
Isotonix® Calcium Plus
Full-Spectrum Support for a Stronger You
Calcium isn't just about strong bones — it's a critical mineral your body needs for dozens of daily functions. That’s why Isotonix Calcium Plus is designed to go beyond the basics. Each form of calcium in our formula is carefully chosen to meet the body’s different absorption needs and physiological demands — helping ensure more complete, targeted support where it matters most.*
Key Ingredients & Benefits
Vitamin D3 (Cholecalciferol)*
Adequate calcium and vitamin D as part of a healthful diet, along with physical activity, may reduce the risk of osteoporosis in later life
Promotes the absorption of calcium and phosphorus
Supports the production of several proteins involved in calcium absorption and storage
Magnesium (Oxide, Carbonate)*
Promotes normal functioning of muscle and nervous tissue
Promotes the normal synthesis of all proteins, nucleic acids, lipids and carbohydrates
Helps combat oxidative stress and lipid peroxidation
Calcium (Carbonate, Lactate, Phosphate, Sulfate, Citrate)*
Supports cardiovascular health
Supports normal muscle contraction and nerve health
Supports healthy energy production
Helps to ease the discomfort of PMS
Manganese (Sulfate)*
Supports healthy blood sugar levels
Promotes normal blood clotting
Supports the normal formation of connective tissue, bones and sex hormones
Promotes normal brain and nerve function
Riboflavin (5-Phosphate)*
Promotes healthy red cell formation and nervous system function
Provides antioxidant support
Promotes energy production
Potassium (Bicarbonate, Citrate)*
Supports proper nerve conduction
Plays a critical role in the normal contraction of cardiac, skeletal and smooth muscles
Maintain Your Frame
Your body needs more than just calcium, it needs the right form, in the right balance, for strong bones, heart health and overall wellness. Packed with an unbeatable blend of essential calcium salts, vitamin C, D and magnesium, this cutting-edge isotonic solution is your ultimate ally for maintaining skeletal health and is key for supporting heart rhythm and normal muscle function. Isotonix® Calcium Plus is ionized upon mixing, making it ready for your body to absorb and use immediately — without waste.
Directions For Use
Pour 1 small capful (3.3 g) of Isotonix Calcium Plus into your favorite cup.
Add 2 fl oz of water for each capful and stir.
For best results, take twice daily — 1 capful in the morning and evening. If mixed with other Isotonix products, add 2 oz of water for each capful.
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
If I am not an elderly woman, why should I take a calcium supplement?
Calcium plays a huge role in regulating many major bodily processes with implications that extend far beyond the age factor. Other than elderly women who may be susceptible to bone loss, younger women, pregnant and lactating women, and men should take a calcium supplement. Younger women need more calcium to build up the strength of their bones. Pregnant and lactating women need extra calcium needs to foster the healthy growth of new cells and of breast milk.
I have heard calcium is great for PMS? How so?
PMS is an undesirable influence on physical and psychological peace of mind. Recent studies have found that over 70 percent of relationships are affected in some way by PMS. So PMS impacts nearly everyone, including men! Supplementation with calcium can reduce PMS symptoms. In a study conducted by the US Department of Agriculture's Human Nutrition Research Center, it was found that women on a high calcium diet had decreased irritability, cramping and bloating associated with PMS. Ovarian hormones affect calcium, magnesium and vitamin D metabolism. Estrogen regulates calcium metabolism, intestinal calcium absorption and parathyroid gene expression and secretion, triggering fluctuations across the menstrual cycle. As a woman menstruates, her hormones are "all over the place." Clinical trials in women with PMS have found that calcium supplementation helps reduce mood and somatic symptoms associated with PMS.
If we only absorb 300 to 400 mg of calcium at a time, why does one serving contain 750 mg?
There are 750 mg of calcium in 2 capfuls of Isotonix Calcium Plus. Therefore, one capful equals 375 mg of calcium. For this reason, it is recommended to only take one capful at a time: one in the morning and one in the evening.
Why is Isotonix Calcium Plus better than other calcium products?
It is better because of the Isotonix delivery system. The secret of the isotonic process is probably now becoming clear! When an isotonic substance enters the body, it will be absorbed into the bloodstream rapidly. With isotonic fluids, little nutritive value is lost making the absorption of nutrients highly efficient. There is nothing artificial about it. An isotonic fluid is nature's own nutrient delivery system.
Why is there left over powder in the cup after mixing with water?
Everyone's water is different; some tap water has a higher concentration of minerals and the pH level of water differs depending on geographic location and the quality of the tap water, which can lead to inconsistencies with the saturation point of a solution. To ensure that our solutions reach the point of saturation, regardless of the pH or mineral levels in water, we have maximized the formulation amounts so that every serving of Isotonix Calcium Plus contains the correct amount of calcium. The residue left in the cup is due to over-saturation which is common in tap water with a higher pH level or a higher mineral content.
What is the best way to store this product?
Keep Isotonix stored in a dry, cool place. If Isotonix are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator – but not in the fruit and vegetables area.
Isotonix® Calcium Plus Research Scope
43%
of U.S. adults do not meet daily calcium requirements from diet alone. (Source: National Institutes of Health, Office of Dietary Supplements).
700
Calcium is involved in the activation of over 700 enzymes essential for the body to function and age well.
65%
Bones are composed of about 65% mineral content, primarily calcium phosphate crystals, which give them strength and structure.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Reviews
Break down of ratings: (88) 5 star ratings. (12) 4 star ratings. (3) 3 star ratings. (3) 2 star ratings. (4) 1 star ratings.
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All the products I order are great
Response from Customer Service on 04/29/2026
Thank you so much for your wonderful review! We're delighted to hear that you've been pleased with all the products, including the Isotonix® Calcium Plus, you've ordered. Your support means a lot to us. If you ever have questions or need help, we’re always here for you. Thank you for choosing Isotonix!
Great product but ...
5 out of 5 star rating.
I wish they would go back to using the measuring cap on the top of the bottle. Having to measure the product in another way takes longer and honestly is just a drag. The old cap was great to use as a measuring cup.
Response from Customer Service on 03/17/2026
Thank you so much for your feedback and for sharing your experience with Isotonix® Calcium Plus. We're delighted to hear you enjoy the product, and we appreciate your comments about the measuring cap.
As part of our ongoing commitment to enhancing the Isotonix experience, we recently refreshed the product’s appearance—including an update to the outer measuring cap. Previously, the cap was clear, and while a small number of customers used it for mixing, most used it primarily to measure water. Our research showed that the majority of our customers prefer to mix multiple Isotonix products together at once in a cup or glass. Based on this, we redesigned the cap to be opaque and optimized it for measuring 2 fl oz (60 ml) of water.
We'll be sure to pass your suggestion along to our product managers for their consideration. Thank you for being a valued member of our community!
Best calcium on the market
5 out of 5 star rating.
With five different calcium combined. This is a great product and helped w my leg cramps.
Response from Customer Service on 03/06/2026
Thank you so much for your great review! We're thrilled to hear that you appreciate the unique blend of calcium sources in Isotonix® Calcium Plus. Your feedback and support mean a lot to us—thank you for being a valued member of our community!
Great taste and works well
5 out of 5 star rating.
I’ve been using Isotonix products for a good handful of years now and I love it. Totally recommend
Response from Customer Service on 01/20/2026
Thank you so much for your wonderful review! We're delighted to hear that you've been enjoying Isotonix® Calcium Plus for years and appreciate your recommendation. Your continued support means a lot to us—thank you for being a valued part of our community!
Best Bioavailable Calcium - Hands down!
5 out of 5 star rating.
Calcium is a hard, hard mineral and not easily digested. Market America makes it simple - pour powder, add water, wait and drink. I feel confident that my 77 year old bones are getting stronger!
Response from Customer Service on 12/23/2025
Thank you so much for your wonderful feedback on Isotonix® Calcium Plus! We’re thrilled to hear how easy and convenient you find the product, and that you feel confident in supporting your bone health. Your trust and satisfaction mean a lot to us. Thank you for choosing Market America and for making us a part of your wellness routine!
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