Get the Daily Nutrition You Need
Get the unmatched delivery and bioavailability of isotonic vitamins and minerals.
4
Provides four of our best-selling Isotonix® products in one convenient purchase
100%
Meets 100% of your recommended daily value of essential vitamins and minerals
Includes our top seller, Isotonix OPC-3®
The super antioxidant in OPC-3 is the pine bark extract, Pycnogenol®‡
Isotonix OPC-3® contains the only isotonic form of Pycnogenol®, a plant extract from the bark of the French maritime pine tree and one of the most clinically researched and powerful bioflavonoids in the world.
Product Classification
Dairy Free
Isotonic
No Detectable GMO
Vegetarian
Good Manufacturing Practices
Gluten-Free
Promoting Health With Savings!
There’s nothing more important than taking care of yourself on a daily basis. With the Isotonix® Daily Essentials Kit, you can be sure that you’re giving your body the essential vitamins, minerals and nutrients it needs thanks to four essential supplements that promote long-term health and optimal nutrition. Plus, by purchasing the Isotonix Daily Essentials Kit instead of buying these products individually, you'll save money!
Key Ingredients & Benefits
Isotonix OPC-3®: Red Wine Extract*
Provides antioxidant support
Helps promote cardiovascular health
Helps maintain healthy circulation by strengthening capillaries, arteries and veins
Isotonix® Multivitamin: Vitamin A*
Contains anti-aging and antioxidant properties
Helps maintain healthy night vision
Promotes normal bone growth
Contributes to a healthy immune system
Isotonix® Calcium Plus: Calcium (as lactate, carbonate, phosphate, sulfate, citrate)*
Helps maintain cardiovascular health
Helps maintain healthy bones, teeth and gums
Isotonix® Activated B-Complex: Folate (Vitamin B9) (as (6S)-5-methyltetrahydrofolic calcium)*
Supplies folate in its biologically active form
Assists in the normal utilization of amino acids and proteins
Isotonix OPC-3®: Pycnogenol®‡, Pine Bark Extract*
Supports the normal dilation of blood vessels
Provides complete antioxidant protection
Combats free radicals
Supports a healthy complexion
Promotes healthy sperm quality
Four Essential Customer Favorites in One Kit
Take control of your health by giving your body the best. For less than the price of a cup of coffee, you can support your body with the nutrition it needs for optimal health. The Isotonix® Daily Essentials Kit includes 90-day servings of Isotonix Multivitamin, OPC-3®, Activated B-Complex and Calcium Plus.
Four Essential Customer Favorites
Isotonix® Calcium Plus: Essential for maintaining strong bones and healthy teeth and gums
Supports skeletal and cardiovascular health
Promotes normal regulation of enzyme and hormone production
Isotonix® Activated B-Complex: Boost your B vitamins with active forms of vitamins B6 and B12
Increases energy and fuels optimal energy production
Promotes a healthy nervous system, bone marrow and intestinal tract and cardiovascular health
Isotonix OPC-3®: The most powerful antioxidant supplement on the market today!
Helps maintain healthy cholesterol and blood glucose levels
Helps maintain healthy circulation by strengthening capillaries, arteries and veins
Isotonix® Multivitamin: Get total nutrition
Contains 100% or more of the Recommended Daily Value of essential vitamins and minerals
Supports a strong immune system and supplements dietary deficiencies
Isotonix Delivery System
:05 minutes
Isotonix Liquid Vitamins
- Formulated to survive digestion.
- Delivers concentrated nutrients to the site of absorption.
- Contains no fillers or binders.
- No artificial color or flavors.
:40 minutes
Standard Vitamin Tablet
- Contains lab-created coatings and lubricants.
- Often contains artificial colors, nutrients and flavors.
- Limited absorption of nutrient utilization.
Frequently Asked Questions
Can the Isotonix Daily Essentials Kit products be taken at the same time?
Yes. The Isotonix Daily Essentials Kit products can safely be taken at the same time, provided that one follows the recommended serving size for each product.
Why are Isotonix supplements better than standard supplements?
Isotonix formulas are more effective than standard supplement formulas because they offer the best way to get the maximum delivery of vitamins and minerals into the bloodstream. Isotonix formulas are also the fastest and most effective way to receive vitamins, minerals and nutrients. The stomach has very little work to do because the pH and tonicity are carefully designed to allow the stomach to quickly release all the nutrients into the small intestine. With the Isotonix formulas, this process takes about five minutes, whereas a standard vitamin tablet can take up to four hours.
What sets Isotonix OPC-3 apart from other bioflavonoid products?
Isotonix OPC-3 offers scientifically supported oligomeric proanthocyanidins, or OPCs, found to be the most powerful antioxidants for human health. In addition to being powerful antioxidants, these individual OPCs have been shown to provide a myriad of specific health benefits. This science-driven selection of OPCs is unique to OPC-3, as is the Isotonix delivery system, which enables rapid and highly efficient absorption of the OPCs. The potent nutrients, in combination with the highly effective delivery system, makes OPC-3 the most powerful free radical scavenging product available.*
Why do I need to take a multivitamin?
A good quality vitamin and mineral supplement creates a sound micronutrient foundation to accompany a balanced diet. Vitamins and minerals help to support a healthy immune system, promote the conversion of food into energy, support a healthy cardiovascular system, support strong bones, promote mental clarity, maintain normal metabolic functioning, promote healthy growth and repair of tissues, help maintain normal blood pressure and help maintain water and electrolyte balance in the body.
What does “Activated” refer to in Isotonix Activated B-Complex?
"Activated" refers to the active forms of vitamins B6 and B12 and folate. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, there are circumstances in which this reaction is either slowed or inhibited.
Why should I take calcium?
According to the Surgeon General, taking a calcium supplement daily is key to preventing and treating calcium deficiency and to helping reduce the risk of osteoporosis.** Currently, osteoporosis affects over one-third of postmenopausal women in this country. Recent clinical statistics also indicate that aging men are also likely to become susceptible to osteoporosis.* Everyone needs calcium. Practically no one ingests enough calcium in their daily diet. Besides being helpful in supporting and maintaining bone integrity, calcium serves a dynamic role as a mineral. It's very important in supporting the activity of many bodily enzymes and maintaining proper fluid balance. Isotonix Calcium Plus also promotes the normal contraction of muscle.
**Adequate calcium and vitamin D, as part of a well-balanced diet, along with physical activity, may reduce the risk of osteoporosis.
I am healthy, so why should I take Isotonix OPC-3?
Everyone is vulnerable to the aging process caused by continuous free radical damage. Athletes tend to be exposed to elevated levels of oxidative stress. Free radicals develop as byproducts during metabolism when calories are processed with oxygen. Athletes inhale 10 to 20 times more oxygen during physical activity over rest periods. The increase in activity creates additional free radicals. These free radicals are known to limit performance, as free radicals appear to take their toll on muscle tissue. Studies on recreational athletes have shown a 20% endurance increase with OPCs, as compared to a control group receiving a placebo. Another study has shown that athletes using OPCs suffered significantly less muscle cramping during and after performing. Isotonix OPC-3 helps to maintain healthy blood flow and this supports oxygen supply to muscles.*
Isotonix® Daily Essentials Kit Research Scope
558+
More than 558 studies have been done on Pycnogenol® and human health
Zero
The number of essential vitamins or minerals the human body can make on its own, making supplementation a prudent step to achieve a healthy metabolism
20%
The percentage of adults that may have a subclinical deficiency in one or more B vitamins due to poor dietary intake
700+
Calcium is involved in the activation of over 700 enzymes essential for the body to function and age well
Reference List
Isotonix® Calcium Plus
- Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density on men and women 65 years of age and older. N Engl J Med. 1997; 337:670-676.
- Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997.
- Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res. 1994; 7:313-328.
- Hussain S, Ali SF. Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats. Neuroscience Letters. 1999; 261:21-24.
- Keen CL, Ensunsa JL, Watson MH, et al. Nutritional aspects of manganese from experimental studies. Neurotoxicol. 1999; 20:213-223.
- Martini LA. Magnesium supplementation and bone turnover. Nutr Rev. 1999; 57:227-229.
- Naghii MR, Wall PM, Samman S. The boron content of selected foods and the estimation of its daily intake among free-living subjects. J Am Coll Nutr. 1996 Dec;15(6):614-9.
- Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994;102:83-85
- Nielsen FH. Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9:61-69
- Penland J.G. The importance of boron nutrition for brain and psychological function. Biol Trace Elem Res. 1998; 66:299-317.
- Saris N-EL, Mervaala E, Karppanen H, et al. An update on physiological, clinical and analytical aspects (review). Clinica Chimica Acta. 2000; 294:1-26.
- Singh MA. Combined exercise and dietary intervention to optimize body composition in aging. Ann N Y Acad Sci. 1998 Nov 20;854:378-93.
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA. 2000; 283:2822-2825.
- Strause L, Saltman P, Glowacki J. The effect of deficiencies of manganese and copper on osteo-induction and on resorption of bone particles in rats. Calcif Tissue Int. 1987; 41:145-150
- Sutherland B, Strong P, King JC. Determining human dietary requirements for boron. Biol Trace Elem Res. 1998 Winter;66(1-3):193-204.
- Volpe SL, Taper LJ, Meacham S. The relationship between boron and magnesium status and bone mineral density in the human: a review. Magnes Res. 1993;6:291-296
- Zemel MB, Shi H, Greer B, et al. Regulation of adiposity by dietary calcium. FASEB J. 2000; 14:1132-1138.
Isotonix® Activated B Complex
- Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
- Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
- Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and
- Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
- Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
- Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
- Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
- Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4(4):249-265, 1999.
- Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise., 17(Supplement):287, 1985.
- Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
- Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
- Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
- Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
Isotonix OPC-3®
- Devaraj, S., et al. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 37:931-4, 2002.
- Fitzpatrick, D., et al. Endothelium-dependent vascular effects of Pycnogenol. Journal of Cardiovascular Pharmacology 32: 509-515, 1998.
- Frankel, E., et al. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet 341: 454-7, 1993.
- Freedman, J., et al. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation 103:2792-8, 2001.
- Frémont, L. Biological effects of resveratrol. Life Sciences 66: 663-673, 2000.
- Miyagi, Y., et al. Inhibition of human low-density lipoprotein oxidation by flavonoids in red wine and grape juice. Am J Cardiol 0:1627-31, 1997.
- Monograph. Vaccinium myrtillus (bilberry). Altern Med Rev 6:500-4, 2001.
- Murias M., et al. Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship. , 2004.
- Nuttall SL, Kendall MJ, Bombardelli E, Morazzoni P. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect. J Clin Pharm Ther 23: 385-89, 1998.
- Packer, L., et al. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radic Biol Med 27:704-24, 1999. Review.
- Schönlau, F., et al. The cosmeceutical Pycnogenol®. J Appl Cosmetology 20: 241-6, 2002.
- Segger, D. and Schönlau, F. Supplementation with Evelle® improves skin smoothness and elasticity in a double blind, placebo-controlled study with 62 women. Journal of Dermatological Treatment 15:222-26, 2004.
- Shi, J., et al. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6:291-9, 2003. Review.
- Wallerath, T., et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation 106:1652-8, 2002.
- Watson, R. Pycnogenol® and cardiovascular health. Evidence-Based Integrative Medicine 1: 27-32, 2003.
Isotonix® Multivitamin (With Iron)
- Anderson RA. Effects of chromium on body composition and weight loss. Nutr Rev. 1998 Sep;56(9):266-70.
- Arthur JR. Functional indicators of iodine and selenium status. Proc Nutr Soc. 1999 May;58(2):507-12.
- Baly DL, Schneiderman JS, Garcia-Welsh AL. Effect of manganese deficiency on insulin binding, glucose transport and metabolism in rat adipocytes. J Nutr. 1990; 120:1075-1079.
- Brown JE, Wahle KW Effect of fish-oil and vitamin E supplementation on lipid peroxidation and whole-blood aggregation in man. Clin Chim Acta. 1990 Dec 14;193(3):147-56.
- Carlisle EM. Silicon as a trace nutrient. Sci Total Environ. 1988; 73:95-106.
- Carlisle EM. The nutritional essentiality of silicon. Nutr Rev. 1982; 40:193-198.
- Couzy F, Lafargue P, Guezennec CY. Zinc metabolism in the athlete: influence of training, nutrition and other factors. Int J Sports Med. 1990 Aug;11(4):263-6.
- Dallman PR. Iron deficiency and the immune response. Am J Clin Nutr. 1987; 46:329-334.
- Daudu PA, Kelley DS, Taylor PC, Burri BJ, Wu MM. Effect of a low beta-carotene diet on the immune functions of adult women. Am J Clin Nutr. 1994 Dec;60(6):969-72.
- Dawson-Hughes B. Vitamin D and calcium: recommended intake for bone health. Osteoporos Int. 1998;8 Suppl 2:S30-4. 6. Feit JM. Calcium and vitamin D supplements for elderly patients. J Fam Pract. 1997 Dec;45(6):471-2.
- Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997.
- Dreon DM, Butterfield GE. Vitamin B6 utilization in active and inactive young men. Am J Clin Nutr. 1986 May;43(5):816-24.
- Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res. 1994; 7:313-328.
- Fields M, Lewis CG. Starch diets high in iron can duplicate the severity of copper deficiency in rats fed fructose. J Med Food. 1998; 1:193-199.
- Finch CA, Huebers H. Perspectives in iron metabolism. N Engl J Med. 1982; 306:1520-1528.
- Futoryan T, Gilchrest BA. Retinoids and the skin. Nutr Rev. 1994; 52:299-310.
- Gleeson M, Bishop NC. Elite athlete immunology: importance of nutrition. Int J Sports Med. 2000 May;21 Suppl 1:S44-50.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
‡As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.
†Sunactive® Fe is a registered trademark of Taiyo International, Inc.
Note: For child safety, Isotonix Multivitamin (with Iron) has a child-resistant cap. The overcap doesn't fit the child-resistant cap, so it will be shipped separately for now if you'd like to use it for measuring and mixing.
Reviews
Customer Rating
4.7 out of 5 star rating.
(44 reviews)
would recommend this product.
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I've been using this product for many many years and love it. I truly believe it helps in maintaining steady levels in my blood work results. I was disappointed the last time I placed an order when, for the first time ever, they were out of the product and it took nearly a month to be filled. It was a terrible inconvenience and I certainly hope it doesn't happen again.
Response from Customer Service on 04/21/2026
Thank you so much for your thoughtful review and for being a loyal customer for so many years! We're delighted to hear that Isotonix® Daily Essentials Kit (With Iron) has been beneficial for you and your wellness. We sincerely apologize for the recent delay with your order and truly appreciate your patience and understanding. Your feedback is important to us as we work to improve our service. Thank you for being a valued member of our community!
POSITIVE
by Anonymous
on 04/05/2026
I have taken this product for many years. I am 87 years old, still driving and alert, and thank GOD and Isotonix for my physical and mental health. Yes, I do have a few minor issues like many older people but nothing big that impairs my daily living. All I can say is, try Isotonix for yourself and see if it helps.
Response from Customer Service on 04/06/2026
Thank you so much for your wonderful review and for being a loyal customer for so many years! We are delighted to hear how Isotonix® Daily Essentials Kit (With Iron) has supported your well-being over time. Your positivity and experience are truly inspiring. Thank you for being a valued member of our community and for sharing your story!
Best Delivery System
by LindsayH
Shop Consultant
on 08/30/2024
I love these products. I take my daily essentials every day to help ensure I get my recommended vitamins, minerals, and antioxidants! The Isotonix delivery system is unmatched. I wouldn't use any other vitamin company.
Response from Customer Service on 08/30/2024
Thank you for sharing your positive experience with the Isotonix® Daily Essentials Kit (With Iron)! We're thrilled to hear that you love these products and take them daily to ensure you get your recommended vitamins, minerals, and antioxidants. It's fantastic to know that you find the Isotonix delivery system unmatched. Your loyalty and positive feedback are greatly appreciated!
Love these!
by JannaS
Shop Consultant
on 08/30/2024
I love that I can drink a serving every morning and know my body is actually getting great nutrients right away! It tastes great and I look forward to taking my vitamins instead of dreading trying to swallow pills.
Response from Customer Service on 08/31/2024
Thank you for your enthusiastic review! We're thrilled to hear that you love the Isotonix® Daily Essentials Kit (With Iron). It's fantastic to know that you enjoy the taste and the convenience of drinking your vitamins every morning. We're delighted that our product makes it easier for you to get the nutrients you need without the hassle of swallowing pills. Your positive feedback means a lot to us. Thanks for sharing your experience and for making us a part of your daily routine!
daily essentials kit w/iron
by MichaelB
on 04/13/2023
good vitamins. have more energy. not happy about price increase. went up $40 since my last order 3 months ago. I like these vitamins but you're pricing me out.
Response from Customer Service on 04/14/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the nutraMetrix Isotonix® Daily Essentials Kit - With Iron! We are so happy to hear you are pleased with the products! We can certainly understand how you feel and nutraMetrix was able to put off this price increase for almost five years. The decision to implement a minimal price increase was not taken lightly, but the change will help us navigate rising costs in our production and supply chain so we can continue to deliver the highest quality of performing products with the very best ingredients and formulations.
Thank you again!
The Product Information Team
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