My Product review-Prime
5 out of 5 star rating. 
Powered by Ingredients with Clinically Relevant Science
Key research insights behind NMN, fisetin and spermidine.
NMN
Supports improvements in physical vitality in adults. Studies show that adults supplementing with NMN experienced improvements in walking speed, grip performance and sleep quality.
Spermidine (Yuth™)
Levels and the body’s ability to absorb it decline with age. Evidence suggests that healthy levels of this compound are associated with healthy aging and longevity.
Fisetin
has strong antioxidant activity and supports cellular health pathways related to healthy aging.
NMN — The Direct NAD+ Precursor
Engineered for fast uptake and powerful cellular support.
NMN is one of the closest precursors to NAD+, helping the body maintain healthy NAD+ levels as they naturally decline with age. Research shows orally administered NMN is absorbed rapidly and supports NAD+ production in key tissues. By helping maintain NAD+ availability, NMN supports mitochondrial function, energy production, metabolic function and cellular health against everyday stressors.
Product Classification
Good Manufacturing Practices
Vegan
No Detectable GMO
Gluten-Free
The Prime™ Approach to Cellular Support
Designed to fuel cellular vitality through multiple supportive pathways.
NMN, fisetin and spermidine each contribute to overall cellular health. NMN supports NAD+ metabolism and cellular energy, fisetin helps defend against oxidative stress and spermidine helps maintain cellular balance. Together, they provide broad foundational support for healthy aging.
Key Ingredients & Benefits
Supports Muscle Performance with Age*
Supports energy production in muscle tissue.
Supports Cognitive Function*
NMN and fisetin support cellular pathways involved in healthy brain function.
Antioxidant support from fisetin supports overall cellular health.
Helps Maintain Metabolic Health*
Spermidine intake is associated with healthy metabolic markers.
Supports metabolic health and helps maintain normal glucose levels.
Supports Antioxidant Activity*
Fisetin is a well-studied antioxidant that helps neutralize free radicals.
Spermidine and NMN support the body’s antioxidant defense systems.
Supports Cellular Energy*
NMN supports NAD+ metabolism, a cofactor essential for cellular ATP production.
Research shows NMN promotes NAD+ metabolites.
Fisetin helps support healthy mitochondrial function.
Spermidine supports overall cellular balance for efficient energy use.
Supports Healthy Aging*
NMN helps maintain NAD+ levels that decline with age.
Spermidine intake may correlate with healthy aging.
Fisetin promotes cellular antioxidant support.
The Future of Cellular Energy Starts Here
Keeping your cellular NAD+ levels at their peak is essential for vibrant energy, optimal mitochondrial functioning and graceful aging. Prime™ NMN harnesses cutting-edge science with a powerful trio of ingredients working in harmony to supercharge cellular health at the foundation while supporting your body’s antioxidant defenses. Choose Prime™ NMN — your partner in biohacking vitality for cellular resilience and a healthier tomorrow.
Frequently Asked Questions
How do Prime™ NMN and Prime™ NAD+ work differently?
NMN and NR are different NAD+ precursors that support the body’s NAD+ pool through distinct metabolic routes. The body regulates NAD+ production, so using both may offer a broader support profile, though more isn’t always better.
Will I benefit from taking both together?
Both can support NAD+ levels, and each influences the pathway differently. Taking both may provide broader longevity supporting benefits, and current research does not indicate safety concerns at typical dosages.
If I take Prime NAD+, should I switch?
Both Prime NAD+ and Prime NMN support NAD+ production; the choice is based on preference for the specific precursor and additional support ingredients.
What products pair well with Prime™ NMN?
Isotonix OPC-3® supports oxidative balance and Isotonix® Activated B Complex helps provide B vitamin cofactors involved in NAD+ metabolism.
What daily amount of NMN supports healthy aging?
Many clinical studies use around 500 mg of NMN. Consistency appears important because NAD+ levels decline after stopping supplementation.
Does this product support men and women equally?
Research suggests NMN and NR support both men and women. Benefits relate more to age than gender.
What are NAD+ precursors?
They are compounds that help maintain NAD+ production pathways, including NMN, NR, NAM, NA and tryptophan.
When is the best time to take it?
Most users take it in the morning with food, aligning with natural energy rhythms.
What else depletes NAD+ levels?
Lifestyle factors such as poor sleep, low activity, smoking, and alcohol can contribute to lower NAD+ levels.
Research Scope
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
†As Yuth. Yuth™ is a trademark of Compound Solutions.
Reviews
Break down of ratings: (7) 5 star ratings. (0) 4 star ratings. (0) 3 star ratings. (0) 2 star ratings. (0) 1 star ratings.
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After three days I noticed I have more energy . I take it in the morning .
Response from Customer Service on 04/24/2026
Thank you so much for your wonderful review! We're delighted to hear that you've noticed more energy after just a few days of taking Prime™ NMN. Your feedback means a lot to us—thank you for being a valued member of our community!
Silent support
5 out of 5 star rating.
Knowing that this is a precursor to the NAD+ I already use, assures me I am getting the very best out of the NAD+. Anything that supports that longevity gene and knowing how this product and others are sourced and manufactured, assures me their superiority.
Response from Customer Service on 04/21/2026
Thank you so much for your thoughtful review! We're delighted to hear that Prime™ NMN gives you confidence in your wellness routine and that you value the quality of our sourcing and manufacturing. Your trust and feedback mean a lot to us—thank you for being a valued member of our community!
Anti-aging is my goal
5 out of 5 star rating.
I was taking NAD+ to look and feel younger and saw that this had the same goal. So I switched to NMN and I continue to feel younger. My grey hair seems to be going back to its original color, so I will continue to take this to see if this continues. Anti-aging is my goal at 79 yrs. old!
Response from Customer Service on 04/20/2026
Thank you so much for your wonderful review! We’re delighted to hear that Prime™ NMN is supporting your anti-aging goals and that you’re noticing such positive changes. Your enthusiasm and commitment to your wellness journey are truly inspiring. Thank you for being a valued member of our community!
Pahrin A Seatts
5 out of 5 star rating.
It has not been quite a month, but I must say that although I never had a problem with going to sleep. I find that I'm now feeling will rested. I'll be 70 years of age this year, and I'm beginning to notice I don't desire that mid day Nap I'm able to push through the day and get all my projects done. NMN has shown positive results in my day to day activity it truly a keeper.
Response from Customer Service on 04/13/2026
Thank you so much for your wonderful review! We're delighted to hear that Prime™ NMN has made a positive change in your daily energy and productivity. It's great to know you’re feeling well-rested and able to accomplish so much throughout your day. Your feedback means a lot to us—thank you for being a valued member of our community!
Great product!
5 out of 5 star rating.
I take this in the mornings before swim practice or workouts. I feel more energetic and helps with stamina. I just do better with it. (My 2 days off U take the Nad+), and I like tat fir a less active day.)
Response from Customer Service on 04/10/2026
Thank you so much for your wonderful review! We're delighted to hear that Prime™ NMN helps you feel more energetic and supports your stamina during your swim practices and workouts. It’s great to know you’ve found a routine that works well for you. Your feedback means a lot to us—thank you for being a valued member of our community!
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